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Rheumatoid arthritis (RA), which causes painful swelling of the joints, is a form of autoimmune disease where otherwise healthy tissue in a patient's joint gets mistaken for an intruder and is attacked by the immune system. Past observational studies have confirmed a correlation between patients with RA and higher levels of periodontal disease (gum disease). Anti-citrullinated protein antibodies (ACPAs) are found in the blood of most patients with RA. Gum disease is specifically more common in individuals with RA who also have ACPAs in their blood. In a study, researchers wanted to investigate whether these overlapping observations could be better...

A perfect bioweapon? Sowing the body with the seeds of self-destruction via most efficient endothelial delivery. ... Spike Protein is a designed viral fragment that has been attached to a coronavirus as a delivery mechanism. This viral fragment causes ARDS, multiple organ failure and death in a very few due to the initial phase of the Syndrome it induces. This is what I have called SPED. Spike Protein Endothelial Disease. The second phase of this Syndrome I had initially thought was a Progeria syndrome. I now no longer believe that to be the case. However, Phase II would certainly be...

Fasting may be detrimental to fighting off infection, and could lead to an increased risk of heart disease, according to a study. Researchers aimed to better understand how fasting—from only a few hours to a more severe 24 hours—affects the immune system. They analyzed two groups of mice. One group ate breakfast right after waking up and the other group had no breakfast. Researchers collected blood samples in both groups when mice woke up (baseline), then four hours later, and eight hours later. When examining the blood work, researchers noticed a distinct difference in the fasting group. Specifically, the researchers...

Biologists have definitively linked the brain's immune system to epilepsy. The researchers lay out a chain of events that can cause seizures—the most common manifestation of epilepsy—to worsen. The sequence begins when oxidative stress in the body causes the brain's immune system to react. That activation by the brain's resident immune cells (called glia) triggers more severe seizures. It’s the first time the brain immune system–epilepsy link has been experimentally proved. "We have provided genetic proof that both oxidative stress and activation of the brain immune system make epilepsy worse," says John Manak, professor. "This is hugely significant because our...

The immunity generated from an infection was found to be “at least as high, if not higher” than that provided by two doses of an mRNA vaccine. Immunity acquired from a Covid infection provides strong, lasting protection against the most severe outcomes of the illness, according to research published Thursday in The Lancet — protection, experts say, that’s on par with what’s provided through two doses of an mRNA vaccine. Infection-acquired immunity cut the risk of hospitalization and death from a Covid reinfection by 88% for at least 10 months, the study found. “This is really good news, in the...

Eric Clapton bravely discusses his neurological COVID-19 vaccine injuries... Why does Eric Clapton’s story matter? He may have been injured by two doses of the AstraZeneca COVID-19 vaccine, but this is not just an “AstraZeneca issue”. This is a spike protein issue - regardless of the platform that delivers the spike protein into your body (Pfizer, Moderna, J&J, AstraZeneca, Novavax, Sputnik, Covishield). Internationally renowned DJ, composer, songwriter Tyson Illingworth suffers Moderna vaccine injuries..

Once again, the free press has been asleep at the wheel. Here is another example of how alternative news sources such as internet bloggers are much more useful to the general public than traditional media sources. A new study out of Germany, funded by the German government, and published in the medical journal Science Immunology, raises the possibility that the so-called vaccine manufactured by BioNTech/Pfizer to fight the mRNA SARS-CoV-2 virus (and possibly the Moderna product), reduces a person’s level of antibodies that fights the virus and increases the level of another kind of antibody that is much less effective...

Well, here's the medical facts that entirely explain why people with more shots get more covid. I've been paying attention to this possibility for a while but until the study work came out that proved it all there was is speculation. ADE ("Antibody dependent enhancement") is a fairly poorly-understood thing; most people believe it is confined to making a particular infection more serious than it would otherwise be. Of course having it occur when it otherwise would not fits that quite-nicely, but isn't what people tend to think about. Now, unfortunately, we have the evidence. Here's the salient graph and...

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial. People with ITP have a type of autoantibody (antibodies directed against a person's own proteins) called immunoglobulin G (IgG) that increases the clearance of platelets from the circulation and can also reduce platelet production. ITP can be very difficult to treat, especially in patients who have not responded well to previous ITP...

Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. At the same time, surprisingly, a cell type of the innate immune defense, the neutrophils, also dramatically decreases. Iron deficiency, a known defense mechanism against infectious pathogens, is a double edged sword, as it simultaneously curbs the defensive power of an important arm of the innate immune system. "This strong iron dependence of neutrophils was previously unknown. It possibly affects the immune defense against bacterial pathogens," says Bruno Galy. Interestingly, on the other...

A lifelong promoter of vaccines suspects he might be the rare, unfortunate exception. On september 22 of last year, Michel Goldman, a Belgian immunologist and one of Europe’s best-known champions of medical research, walked into a clinic near his house, rolled up his sleeve, and had a booster shot delivered to his arm. He knew he’d need it more than most. Just a few weeks earlier, Michel, 67, had been to see his younger brother, Serge, the head of nuclear medicine at the hospital of the Université Libre de Bruxelles, where both men are professors. Michel was having night sweats,...

A genetically-engineered cold sore virus is the new hope to beat cancer after scientists found it could eradicate or shrink tumours in terminally ill patients. Patients were injected with the weakened form of the herpes simplex virus that has been modified to kill cancer cells in an early trial at the Institute for Cancer Research (ICR) in London. The injection is given directly into the tumour, attacking it in two ways — by invading the cells and making them burst and boosting the immune system. RP2 was tested on 39 patients with cancers including people suffering from skin, oesophageal and...

People who got “vaccinated” for the Wuhan coronavirus (Covid-19) while in remission for cancer are finding that their cancer has returned. Bonnie Eisenberg, a 73-year-old who has been eight years in remission for breast cancer, is one such person who thought she was done with her disease in 2014. Up until the time she got jabbed, Eisenberg’s cancer appeared to be gone – but no longer. Her tumor markers have increased, including levels of carcinoembryonic antigen (CEA), which is common to cancers of not only the breast but also the colon, rectum, prostate, ovary, lung, thyroid, and liver. Every month...

VIDEO (both speak English well, but there are subtitles) This hour and a half interview covers everything from the SARS CoV-2 virus, to the VAERS system and the victims of the Pfizer, Moderna and Johnson & Johnson's injections. These are the chapters:00:00:00 - Recap 00:02:00 - introduction by Avi Barak 00:05:05 - introducing Dr. Rose and her Background 00:09:30 - About the SARS-CoV-2 virus 00:18:05 - About the mRNA technology 00:29:02 - The data from the Vaccine Adverse Event Reporting System 00:48:38 - How the CDC is ignoring its own data 00:51:01 - Pregnancy, Embryo-genesis and Reverse transcription 00:57:10 -...

Elite tennis players have an uncanny ability to clear their heads after making errors. They constantly move on and start fresh for the next point. They can’t afford to dwell on mistakes. Peter Strick is not a professional tennis player. He’s a distinguished professor and chair of the department of neurobiology at the University of Pittsburgh Brain Institute. He’s the sort of person to dwell on mistakes, however small. . . . . . .For a long time, it has been understood that the adrenal glands were turned on and off by a couple discrete pathways coming from the brain....

Children are turning up in doctors' clinics infected with as many as three different types of viruses, in what experts believe is the result of their immune systems being weakened from two years of COVID lockdowns and mask-wearing. Medical staff have come to expect a surge in cases of flu and severe colds during the winter. But they are reporting that there is not the usual downturn as summer approaches - and they suspect it could be due to the strict pandemic practices. Furthermore, some of common strains of the flu appear to have disappeared, flummoxing scientists. Thomas Murray, an...

Researchers have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease. Rapamycin is approved to treat transplant and cancer patients. Publicly available data suggest that the drug might also improve learning and memory in aged mice. However, the researchers observed that after rapamycin treatment, a protein called Trem2 (triggering receptor expressed on myeloid cells 2) is dramatically diminished. Trem2 is present in microglia, which are immune cells in the brain and spinal cord. "Trem2 is a receptor located on the surface...

A combination of chemotherapy with an immunotherapy meant to unleash the anticancer capacity of the immune system was effective against one of the hardest targets in cancer care, pancreatic cancer, in a national, randomized clinical trial. The researchers found that in 34 patients with advanced pancreatic cancer randomized to receive the immunotherapy nivolumab with two chemotherapy drugs, nab-paclitaxel and gemcitabine, had a one-year survival rate of 57.7 percent, significantly greater than the historical average of 35 percent with chemotherapy alone. The findings also included the identification of immune system biomarkers associated with better outcomes. A ray of hope has come...

In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid. The research team studies illnesses which are caused by misfolded proteins, of which Alzheimer's disease in the brain is the most well-known example. The researchers noted that there are many similarities between COVID-19-related symptoms and those which are observed in illnesses caused by misfolded proteins. Using computer simulation, the researchers discovered that the coronavirus'...

It is well established that older adults are more susceptible to infection and their immune systems less capable of generating a strong immune response. Findings suggest that lymph nodes, which are critical for maintaining and revving up the immune response during infection, age at different rates. Lymph nodes closer to the skin deteriorate two to three times more quickly than those deeper in the body. White blood cells, specifically T cells, are the soldiers of the immune system. T cells are made by the thymus, a gland that sits below the chest bone and above the heart. The thymus quickly...