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In a paper published in the journal Nature, bioengineers at The Scripps Research Institute in the San Diego neighborhood of La Jolla said they had successfully inserted two synthetic molecules into the genome of an Escherichia coli bacterium, which survived and passed on the new genetic material. In addition to the naturally occurring nucleotides adenine, thymine, guanine and cytosine, which form the rungs of DNA’s double-helix structure, the bacterium carried two more base-pair partners, which study authors have dubbed d5SICS and dNaM. For more than a decade, scientists have been experimenting with so-called unnatural base pairs, or UBPs, saying they...

For the last decade cancer research has been guided by a common vision of how a single cell, outcompeting its neighbors, evolves into a malignant tumor. Through a series of random mutations, genes that encourage cellular division are pushed into overdrive, while genes that normally send growth-restraining signals are taken offline. With the accelerator floored and the brake lines cut, the cell and its progeny are free to rapidly multiply. More mutations accumulate, allowing the cancer cells to elude other safeguards and to invade neighboring tissue and metastasize. These basic principles — laid out 11 years ago in a landmark...

Signature in the Cell makes 2009 list of top ten bestselling science books Today Amazon.com announced their bestselling books of 2009 and Signature in the Cell: DNA and the Evidence for Intelligent Design (HarperOne) by Dr. Stephen C. Meyer made the top ten in the science category. According to Amazon.com, books on its 2009 list of best sellers are “[r]anked according to customer orders through October. Only books published for the first time in 2009 are eligible.” The book's publisher, HarperOne, reports that the book is entering its fifth printing in as many months, and continues to sell strongly both...

It is now clear that genetics won’t be able to answer all of our questions about human development and disease. These basic biological processes rely heavily on epigenetics – the ability to ‘fine-tune’ the expression of specific genes. This regulation of gene expression is essential for defining cellular identity and the dysregulation of these processes results in a variety of human diseases. Therefore, understanding these mechanisms will not only enhance our basic knowledge but will also lead to the improved detection, therapy and prognoses of several human diseases. ... The histone code hypothesis predicts that the post-translational modifications of histones,...

Loren Williams/Chemistry and Biochemistry, Georgia Institute of TechnologyIn a living cell, the DNA double helix wraps around a nucleosome, above center, and binds to some of its proteins, known as histones. Researchers believe they have found a second code in DNA in addition to the genetic code. The genetic code specifies all the proteins that a cell makes. The second code, superimposed on the first, sets the placement of the nucleosomes, miniature protein spools around which the DNA is looped. The spools both protect and control access to the DNA itself. The discovery, if confirmed, could open new insights...

Frederick T. Zugibe, M.S., M.D., Ph.D., FCAP,  FACC,  FAAFS      HOMECONTACT FORENSIC PATHOLOGY & MEDICINE Biography Publications News Public Health Psychotropic  Drugs Study   CRUCIFIXION and SHROUD STUDIES Crucifixion & Shroud Involvement Barbet Revisited Man of the Shroud was Washed Texas Lecture Paris  Lecture Turin 2000 Lecture MISCELLANEOUS: The Code for Human Life                                                          THE CODE FOR HUMAN LIFE  [Reprinted from the Catholic Answer 9: 40-45,1996]     A fertilized human egg at the moment of Conception, is the opinion of the creator that a human life at that instant, must begin.... F. Zugibe    ...