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A type of bacteria that causes dental plaque may be behind a treatment-resistant form of colorectal cancer, a study published Wednesday in the journal Nature found. The particular bacterium, which appears to shield tumor cells from cancer-fighting drugs, was found in 50% of the tumors tested in the study. The discovery, experts say, could pave the way for new treatments and possibly new methods of screening. Colon cancer is the second-leading cause of cancer deaths in the United States and is expected to kill more than 53,000 people in the nation in 2024, according to the American Cancer Society. Rates...

Amid recent reports of exploding cancer rates around the world, a recent revelation from a top pathologist has shed light on the “phenomenon” affecting many of those who received the COVID-19 vaccine. Last week, explosive reports emerged that cancer rates in young people soared by 79 percent, while deaths have risen 28 percent, as studies suggest the trend will continue to increase by 31 percent into 2030.

Doctors across the world are sounding the alarm over a surging epidemic of young people being diagnosed with cancers more commonly associated with the elderly. Between 1990 and 2019, cases of cancer in young people across the globe have increased by 79 percent and deaths have risen 28 percent. Studies project diagnoses will continue to rise by 31 percent and deaths will rise by 21 percent in 2030. Nearly every continent is experiencing an increase of various types of cancer in people under 50 years old, which is particularly problematic as the disease tends to be caught in later stages...

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A blood test to screen for colorectal cancer in average-risk individuals without symptoms accurately detected the malignancy in 83% of people confirmed to have the disease, a study released Wednesday showed. The study was published in The New England Journal of Medicine. Researchers said the blood test's accuracy rate for colorectal cancer is similar to at-home stool tests. It's a promising step, they said, to developing more accessible screening tools for catching the disease early -- when it's easier to treat. The test would could improve upon low levels of colorectal cancer screening -- a major cause of cancer-related mortality...

A cancer drug duo more than doubled the survival of people battling the most common form of advanced bladder cancer, trial results show. Patients who took a combo of meds called EV+P—enfortumab vedotin and pembrolizumab (Keytruda)—had an average of 31.5 months survival, compared to just over 16 months for those on standard chemotherapy, researchers reported. "This is revolutionary for patients," said Dr. Jean Hoffman-Censits. "It's a practice-changing study, where we're nearly doubling the overall survival for patients with locally advanced and metastatic urothelial cancer," she said in a news release. Urothelial tumors are the most common form of bladder cancer....

Researchers have found a way to stop active cancer cells in their tracks – meaning they can then be eliminated by new drug treatments. A collaborative research project between the University of Dundee’s Drug Discovery Unit (DDU) and Queen Mary University of London, has identified chemical compounds, called tool molecules, that can halt active cancer cells. Advancing Cancer Therapy Through Collaboration.. Using these tool molecules forces tumor cells from a specific type of breast cancer into a pro-senescence state – similar to a sleep-like state in which they can no longer divide or cause tumor growth. This condition makes the...

Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease. "Our findings have significant implications: viruses cause between 10% to 20% of cancers worldwide. Treating virus-induced cancers with standard cancer therapies can help shrink tumors that are already there, but it doesn't fix the underlying problem of the virus," said Jun Zhao, Ph.D. The study reveals that KSHV manipulates two human enzymes called CDK6 and CAD...

People who are diagnosed with head and neck cancer often receive a standard type of chemotherapy as part of their treatment. If they are exposed to secondhand smoke during chemotherapy—even if they have never smoked themselves—the treatment may be far less effective at killing cancer cells. In her laboratory, Queimado and her team exposed head and neck cancer cells to secondhand smoke for 48 hours (a control group of cancer cells was not exposed to secondhand smoke). Simultaneously, the cells were treated with cisplatin, a chemotherapy drug commonly used to treat head and neck cancer. The findings were significant: Twice...

Doctors at the World Professional Association for Transgender Health repeatedly struggled with various side effects of what they call “gender-affirming care,” including cancer in teens, reduced sexual function, and the lack of informed consent for procedures with lifelong impacts, newly unearthed documents reveal. WPATH, a controversial organization that transgender advocates and health agencies use to justify “transgender” medical interventions, frames itself as the leading expert organization on medical care for people who identify as transgender. It has faced criticism for advocating experimental practices that ignore serious concerns about informed consent and long-term side effects. Journalist Michael Shellenberger released a report,...

edical professionals were aware of at least one case of cancer thought to be linked to a hormonal medication taken to aid gender transitioning, leaked documents from a worldwide transgender nonprofit organization suggests. In a report released Monday, the think tank Environmental Progress published hundreds of messages it said were from an internal forum of members of the World Professional Association for Transgender Health (WPATH), in which they discussed gender-affirming treatment and the complications that had arisen from particular cases. The report comes amid a national debate on gender-affirming health care, as states across the U.S. have introduced legislation to...

Scientists examined how butyrate, one of the short-chain fatty acids found in the gut, suppresses the growth of different colon cancer cells in the laboratory. The results show that the benefit of butyrate is specific to the cell line studied and is apoptosis-dependent, a process of gene-directed cell death (this a molecular mechanism that plays a crucial role in removing damaged or mutated cells selectively from tissues in an orderly manner). Diet composition is among several factors that can contribute to the prevention of colon cancer. Consuming a healthy diet that is high in fiber can help maintain a healthy...

A study found that a single dose of Bacillus Calmette-Guérin (BCG), the vaccine for tuberculosis (TB), reduced liver tumor burden and extended the survival of mice with liver cancer. The study is the first to show the promising effects of the vaccine in treating liver cancer. Hepatocellular carcinoma (HCC) is the most common type of liver cancer. BCG, the century-old TB vaccine, is considered safe and widely used around the world. BCG is also known to boost the body's immunity. The U.S. FDA has approved it for the treatment of bladder cancer. Yet, the potential effect of BCG in treating...

A new study has discovered a naturally occurring compound found in fruit has the potential to be an effective alternative treatment for colon cancer. A team of international scientists have found a polyphenol called Schisandrin B (Sch B) exhibits a remarkable anti-tumorigenic effect on colon cancer. The compound is found in the fruit of Schisandra chinensis, also known as the magnolia or five-flavor berry, which is native to forests of Northern China, the Russian Far East, and Korea. Wild varieties are also found in Japan and it is often used in plant-based foods and drinks. Existing research has shown Sch...

Stress is inevitable. Chronic stress can increase our risk for heart disease and may also help cancer spread. How this works has remained a mystery. They discovered that stress causes certain white blood cells called neutrophils to form sticky web-like structures that make body tissues more susceptible to metastasis. The finding could point to new treatment strategies that stop cancer's spread. The team arrived at their discovery by mimicking chronic stress in mice with cancer. They first removed tumors that had been growing in mice's breasts and spreading cancer cells to their lungs. Next, they exposed the mice to stress....

Bladder cancer is one of the more common cancers worldwide. Intravesical bacillus Calmette-Guerin (tuberculosis vaccine) has been used as adjuvant therapy by urologists since 1976. Unfortunately, BCG fails approximately 40% of patients in two years. Since 2012, BCG has been in a worldwide shortage situation. One of the most promising new strategies for NMIBC is the combination of intravesical chemotherapy drugs used as sequential therapy, one drug after the other, with one-hour bladder dwell time for each drug. Initial results with gemcitabine (Gem) and mitomycin C (MMC) appeared promising but shortages in MMC led to the need to substitute docetaxel...

Many cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved through expedited ("fast track") pathways, finds a study published by The BMJ. Despite pharmaceutical industry claims that high drug prices are needed to offset research and development (R&D) costs, the results show that more than half of these drugs, including those with minimal or no added benefit, recover R&D expenses within three years. As such, the researchers call for better alignment between regulatory and reimbursement processes, particularly for drugs approved through expedited pathways, to promote development of the...

A new study has discovered that tattoo inks could be linked to cancer or organ failure. An analysis of 54 inks commonly used in tattoo parlors across America has uncovered that a staggering 45 of them contained unlisted additives, including chemicals known to pose alarming health risks. Multiple inks contained 2-phenoxyethanol, which can cause toxic effects in high doses. Researchers involved in the study found the most common additive to be polyethylene glycol, which is a compound that can cause acute renal failure. The study was led by Jonn Swierk from the Department of Chemistry at Binghamton University, and was...

Gary Sinise, the star of “CSI: NY,” has revealed that his son, McCanna “Mac” Sinise, died at 33. Mac died Jan. 5 after a five-and-a-half year battle with chordoma, a rare form of cancer. On Tuesday, the Gary Sinise Foundation took to Instagram to share a picture of Mac with the caption, “In Honor & Memory of McCanna ‘Mac’ Sinise 1990-2024.” Sinise, 68, had Mac with his wife, Moira Harris – the couple has been married since 1981, and also have daughters Sophie and Ella. Sinise, who has won an Emmy, a Golden Globe and a Tony, is also known...

There appears to be a significant link between the coffee intake of people with intestinal cancer and mortality, as well as the likelihood of the disease returning after remission. A team in which researchers participated have reached this conclusion. Previous research showed that coffee consumption reduced the risk of intestinal cancer. This new study investigated whether coffee also impacts the disease's progression. The researchers compared coffee intake to the return of the disease after remission and the mortality among patients. A total of 1,719 patients were questioned about their lifestyle, including the question of how much coffee they drank. The...