Posted on 05/11/2014 3:23:02 PM PDT by Rashputin
Good on you. Anytime you can figuratively poke a stick at them, go for it.
Muslims Rebuild the Temple of Babel !
Take a peek at the video . . .
Humans are not a dead end host for H5N1 at all. This is why there was such concern with the Egyptian clade, which had lower lethality and was primarily a pediatric form.
In fact, humans would be an ideal host for H5N1. With somewhere between 7-8 billion humans, we are a primary target for any opportunistic pathogen. And with a 7 day to 2 week incubation period, large collections of people would be like a flock of chickens, seemingly healthy, and by the next day, all dead or dying.
The five mutation barrier to humans just needs to be broken in the right place, like an urban area. Because it is a novel pathogen, it would take far less of it to cause an infection, a fraction of the amount of ordinary influenza.
And it has a far greater number of animal vectors than it typical, including those with very different immune systems.
I reported what was on the CDC website. No other island was listed there as having the disease.
The Muslim world’s deadly virus is here — living in the White Hut.
Sort of like the health risks of gay parenting, or of gay behavior on the genitourinary systems, here in America.
Enough retards do this and the virus will have time to mutate and allow for human to human transmission.
FReegards,
The Spelling Police
The reason that I say that humans are a dead end host for the H5N1 virus is that it is still essentially a bird virus. The cell receptors that the H5 hemagglutinin binds, those with the alpha 2,3 sialic acid linkage, are only found in the lower respiratory tract in humans. Since the influenza virus can only transmit easily if it binds cells of the upper respiratory tract—those with the alpha 2,6 linkage—the H5N1 is almost non-communicable between humans. It is not transmitted through aerosols, but only through contact with infected fluids. Furthermore, because humans sick with H5N1 are kept in isolation, the virus has no chance to passage between humans, and thus has no selective pressure to make it H2H transmissible. Four of the mutations identified as necessary for H2H transmissibility affected H5 binding affinity. The other mutation affected one of the viral RNA polymerases (I forget which one), but this enables the virus to reproduce at a lower temperature, making it more suitable for growth in the human upper respiratory tract than in the bird gut.
For an H5N1 virus to spontaneously develop all 5 mutations in the course of a single human infection is possible, but highly unlikely. It would have to develop those mutations within the bird host—and since the mutations would make it less adapted to birds, those mutations would probably disappear soon after emerging.
The virus would be more likely to make the requisite mutations in a swine host, since swine have both alpha-2,3 and alpha-2,6 receptors in their trachea. I do not know to what extent H5N1 has affected pigs, if at all.
One last detail is that the tropism of the H5N1 for the lower respiratory tract is one of the factors making it so pathogenic. If the H5N1 were to develop tropism for the upper respiratory tract, it would cause less severe disease. This was observed in the ferret experiments done by Fouchier and Kawaoka.
There you go again coward. Lie some more why don’t you. (Oh yeah....WHERE IS WKUMAN’S SUPPOSED QUOTE LIAR? HUH? POST IT TURD!). The Dawgs object to anyone bashing America, as you do constantly, after taking a run out powder to where you are stuck in. Or encouraging FReepers to have an “escape plan”. Your “Washing Machine”, as you call your wife: “Mista Alec, Mista Alec, More wine? You always bash America good then!” Alex: “Damn it no! Get on those freakin’ dishes.....I’ll call for more wine when I demand it! WM: “As you command my master. WM now go.” WHERE IS THE QUOTE little TURD?
H5N1 in a herd of pigs was observed a long time ago by the chief epidemiologist of Vietnam. He determined that each pig had several variants vying for supremacy in the individual animal. Then each dominant variant would contend with the dominant variants of the other pigs to produce a “grand champion”.
He compared this process to being like a small part of a gigantic computer, made of tens of thousands of herds and flocks.
I have seen no comparison of ARDS in lower vs. upper respiratory tract infections, so cannot attest to differences in severity or mortality.
Thanks for the ping!
Except for the part that, being part of the Malay peninsula, isn't an island.
Posting again from deep in the dark and dingy depths of dipsomaniacal degradation?
You, of course, are right - I didn't see value in arguing with them about the truth. I didn't list Malaysia because it wasn't on the CDC list, the Philippines was. That list changes every day as they find more cases.
I still say I wouldn't want to be on ANY island that had cases because your land space to travel is limited to that island unless you swim away, get away by boat, or fly out.
I value my membership in the Dawgs, patriots of these United States.
Okay, just seeing on Fox the second case here is in Florida. This person was also a healthcare worker, this time in Saudi Arabia. Fox doctor says it passes from person to person if there is close contact which a healthcare worker who treats the patient has. So, in a family, if members take care of a family member who has it, which is close contact, it is likely they will get it.
Typically, a lower respiratory tract infection is more severe and deadly, since the inflammation interferes with the ability to breathe and with gas exchange. Some of these patients can be saved with ECMO. The virus can also spread from the lungs to other parts of the body like the brain, where it is very likely to be fatal. I seem to recall that this is what happened with the imported case of H5N1 in Canada a few months ago--the patient died of brain inflammation. (Interesting point: I should look up the type of receptors predominant in the brain, whether they are alpha-2,3 or alpha-2,6.)
Typically, influenzas confined to the upper respiratory tract cause more mild disease and are highly communicable. The ability to breathe is not as impaired. Of course, even seasonal influenzas kill, but the CFR isn't even close to that seen with the avian influenzas.
If they did find out it was from Islamists screwing their goats or camels, do you think the media would “protect all things Muslim” and LIE about the cause of the disease?
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