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The Latest Man-Made Organs - How science is rebuilding you, bit by bit
popsci.com ^ | 09.17.2008 | Elizabeth Svoboda

Posted on 10/10/2008 12:44:43 AM PDT by neverdem


Artificial Bladder: John Carnett

Almost 100,000 people languish on organ-transplant waiting lists. But new tissue-fabrication techniques should make swapping in a man-made liver as easy as snapping Lego bricks into place.

Blood vessels Method: 3-D printer When: 5 years Gabor Forgacs, a tissue engineer at the University of Missouri, is making blood-vessel networks by culturing three types of vessel cells and loading them into a fridge-size bioprinter. This machine prints out the cells to build capillaries in preprogrammed patterns.

Liver Method: Grown using stem cells from umbilical-cord blood When: 15–25 years Colin McGuckin has made silver-dollar-size, functional “mini livers.” They aren’t large enough to do a full body’s worth of work, because livers have hard-to-replicate ducts with specialized cells.

Kidney Method: Grown on a polymer framework When: 10–20 years His artificial bladder breakthrough in 2006 grabbed all the headlines, but Anthony Atala of the Wake Forest Institute for Regenerative Medicine is forging ahead on other artificial organs. In 2002, when he transplanted artificial kidneys into cows, the organs survived for months and even produced their own urine, albeit not very efficiently. But to build one for humans, he has to figure out the precise combination of seeder cells that will transform a lab-built scaffold into a fully functioning, transplantable organ.

Instant Expert: Launch Your Quick and Easy Primer on Just About Everything at popsci.com/instantexpert.


TOPICS: Culture/Society; Extended News; Technical
KEYWORDS: medicine; regenerativemedicine; stemcells
Organs without a complete vasculature will probably be useless.
1 posted on 10/10/2008 12:44:44 AM PDT by neverdem
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To: neverdem

Perfectly good human organs with a government ban on any compensation are certainly useless...


2 posted on 10/10/2008 1:03:15 AM PDT by BobbyT
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To: neverdem

My wife needs a knee.

Seriously, this is great stuff, but it is going to be for the very rich and well connected. Society won’t be able to afford it for everyone.


3 posted on 10/10/2008 5:50:16 AM PDT by Pearls Before Swine (Is /sarc really necessary?)
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To: neverdem

Is this related to the e-mails that keep offering to add extra inches to my organ?


4 posted on 10/10/2008 9:39:45 AM PDT by steve-b (Intelligent design is to evolutionary biology what socialism is to free-market economics.)
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Link to the heart-growing thread as well:

http://www.freerepublic.com/focus/f-news/2102089/posts


5 posted on 10/10/2008 2:37:20 PM PDT by Titan Magroyne ("Drill now drill hard drill often and give old Gaia a cigarette afterwards she deserves it." HerrBlu)
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To: Drumbo

Just name-dropping. (Last paragraph of article)

:o)


6 posted on 10/10/2008 2:42:21 PM PDT by Titan Magroyne ("Drill now drill hard drill often and give old Gaia a cigarette afterwards she deserves it." HerrBlu)
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To: steve-b
I'm frequently complimented on the size and appearance of my organ...


7 posted on 10/10/2008 2:45:07 PM PDT by Joe 6-pack (Que me amat, amet et canem meum)
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