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Depression gene found
News.com.au ^ | 02/26/2006 | By Clair Weaver and Andrew Chesterton

Posted on 02/25/2006 8:22:24 AM PST by oxcart

IN a world first, researchers from NSW have discovered the gene responsible for depression.

After 25 years' research, scientists have found that people who carry a particular gene are more likely to suffer depression regardless of their life experiences. The medical breakthrough will have major ramifications for diagnosis and treatment of the disease which affects one in four Australians.

The study, to be published in the prestigious British Journal of Psychiatry this week, shows that people who carry a short serotonin transporter gene are predisposed to depression.

Conversely, those who carry a long version of the serotonin transporter gene would be more resilient to whatever life throws at them.

Around 43per cent of the population is believed to carry the short version of the gene.

The breakthrough comes in the wake of a series of recent high-profile cases of depression, including former WA premier Geoff Gallop, the late rugby league legend Steve Rogers and former state opposition leader John Brogden.

Former Australian Olympic swimmer John Konrads and actor Garry McDonald were also sufferers. It is hoped the findings could be used to pre-warn carriers of their susceptibility and take early preventative treatment.

Mr Konrads described the breakthrough as exciting.

"I think it's wonderful to think that people who might have that doubt could confidentially find if they're conducive to depression or not, that would be fantastic," he said.

The serotonin transporter gene, which is responsible for our uptake of "feel good" serotonin and mood control, has been implicated in depression before - but this is the first and most conclusive evidence of its true role.


TOPICS: Culture/Society; Extended News
KEYWORDS: depression; depressiongene; disorders; gene; genetics; health; itwasattheduallalong; medicine; mentalillness; serotonin
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A real breakthrough or another way to sell pills?
1 posted on 02/25/2006 8:22:26 AM PST by oxcart
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To: oxcart

Meet Gene.

2 posted on 02/25/2006 8:26:12 AM PST by martin_fierro (< |:)~)
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To: oxcart
A real breakthrough or another way to sell pills?

One does not exclude the other; and for people who need the therapy it could be a lifesaver.

3 posted on 02/25/2006 8:30:01 AM PST by Publius6961 (Multiculturalism is the white flag of a dying country)
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To: oxcart

Who knows. I can guaruntee I have a crummy gene for this. I spend a great deal of effort being not depressed. Let alone happy.


4 posted on 02/25/2006 8:31:09 AM PST by Crazieman (6-23-2005, Establishment of the United Socialist States of America)
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To: oxcart

interesting


5 posted on 02/25/2006 8:32:03 AM PST by not-alone
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To: oxcart

This is good info for those of us who have always realized it runs in families. Finally nice to have some proof to work with.


6 posted on 02/25/2006 8:32:07 AM PST by Mrs. Shawnlaw (No NAIS! And the USDA can bugger off, too!)
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To: Publius6961

So how I can I make sure my next wife doesn't have this gene?


7 posted on 02/25/2006 8:32:48 AM PST by DannyTN
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To: Crazieman

Try exercise (running), its the only thing that keeps me sane.


8 posted on 02/25/2006 8:34:23 AM PST by oxcart
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To: oxcart
I suffer from depression - strong family history. I get on with life the best I can - I've got a supportive wife and kids. But I feel like crap virtually every day. If I could go home to be with the Lord I would, but I'm no quitter,

If this is truish, it will be one in the eye for all those who tell me it's somehow my own fault.

We'll wait and see
9 posted on 02/25/2006 8:36:24 AM PST by vimto
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To: Mrs. Shawnlaw
Yes, I always knew that serotonin/tryptophan played an important role in depression. I worked in a health food store and the people that took L-Tryptophan swore by it.
10 posted on 02/25/2006 8:41:05 AM PST by oxcart
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To: oxcart

So there is a device that can measure depression ?

Seems like a discovery of an invention like that would be more news than a gene, since there is nothing people can do to change there genes but think of what could be done with a depression measuring machine?

For example, hook it up to the spouse, install them in restaurants, movie theaters, the possibilities where satisfaction needs to be benchmarked are endless!


11 posted on 02/25/2006 8:41:56 AM PST by seastay
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To: oxcart; sure_fine

"...affects one in four Australians..."

Wow, isn't 25% of the population, a pretty high number?


12 posted on 02/25/2006 8:43:22 AM PST by butternut_squash_bisque (Borders, Language, Cultureā„¢)
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To: oxcart

L-tryptophan - is it availalbe in the UK as an over the counter...? I seem to remember that it was used in Psychiatry years ago for depression but it was only available on prescription.

I take venlafaxine \ effexor.


13 posted on 02/25/2006 8:44:43 AM PST by vimto
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To: oxcart

L-tryptophan - is it availalbe in the UK as an over the counter...? I seem to remember that it was used in Psychiatry years ago for depression but it was only available on prescription.

I take venlafaxine \ effexor.


14 posted on 02/25/2006 8:44:50 AM PST by vimto
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To: vimto

Hang in there, I still battle with it also. The good Lord, exercise and a little L-Tryptophan keep me sane.


15 posted on 02/25/2006 8:45:35 AM PST by oxcart
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To: vimto

Hang in there, I still battle with it also. The good Lord, exercise and a little L-Tryptophan keep me sane.


16 posted on 02/25/2006 8:45:53 AM PST by oxcart
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To: oxcart

Doctor please, some more of these
Outside the door, she took four more
What a drag it is getting old


17 posted on 02/25/2006 8:46:09 AM PST by TheForceOfOne (Memogate was Dan Rathers Little Big Horn, Buckhead has the scalp to prove it!)
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To: oxcart
Depression gene found in dumbocRATs after 2000 and 2004 elections!!
18 posted on 02/25/2006 8:47:20 AM PST by Arrowhead1952 (Change tagline as needed,)
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To: oxcart

This news is depressing


19 posted on 02/25/2006 8:47:46 AM PST by digger48
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To: vimto

There was a problem with a bad batch of L-tryptophan that killed half a dozen people - not available in the US any more (except by prescription I think). I tried 5-HTP, another serotonin precursor, but that made me feel worse.

Mrs VS


20 posted on 02/25/2006 8:48:08 AM PST by VeritatisSplendor
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