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Mexico City Wide Innovative Population-Level Study Administers Ivermectin-based Home Kits with Drastic Reduction in Hospitalizations
Trial Site News ^ | 05/08/2201

Posted on 05/17/2021 5:56:43 PM PDT by SeekAndFind

The nation of Mexico generally, and more specifically Mexico City, one of the world’s most populated cities with 22 million people, experienced a greater spike in COVID-19 cases by December 2020. It was at the end of 2020 that the Mexico City Government, concerned about hospital capacity, implemented an expanded population-based health intervention to manage COVID-19. Based on the growing data available from ivermectin research, the government organized a prehospital home-care program combining early detection with antigen tests, a phone-based monitoring process for positive patients and the provisioning of a medical kit containing ivermectin.

Testing, based on World Health Organization (WHO) recommendations, was extended into a massive testing program in 230 temporary mobile units or “kiosks.” Fundamental in the Mexican mission: lower access barriers to identifying COVID-19 at early stages, reduce opportunity for transmission via home isolation and care for patients early, right at onset, even if asymptomatic or mild symptoms. The overall study commenced July 8, 2020 with 3,000 tests administered daily and by the middle of November, the government expanded capacity to 24,000 daily tests. Again, public health workers followed up on those deemed positive via Locatel, (Mexico City Government call center) or WhatsApp text service. During that call, patients are informed if they are positive, asked if they can be in isolation, and the symptoms, if escalated, prompt a more intensive monitoring protocol (e.g. every couple days in more severe cases). Serious cases prompt 911 and hospitalization. 

Since December 28, the ivermectin-based medical kits were distributed to mild to moderate symptomatic patients. The Mexico City Government sought to measure the effectiveness of this population-wide intervention inclusive of the ivermectin-based medical kit in overall hospitalization during the pandemic. Using a quasi-experimental research design involving a Coarsened Exact Matching method leveraging hospital and phone call monitoring data, the study team estimated logistic-regression models with a range of observational data and found a significant reduction in hospitalizations among the cohort receiving ivermectin-based medical kit. In fact, the range of positive effect totaled 52% to 76% depending on model specification. The team concluded that ivermectin-based interventions in a well-designed population-level scheme mitigates the effects of the COVID-19 pandemic on the health system in the world’s fifth largest city. TrialSite includes diagrams of the impact these population-level schemes have had in the region. The results should trigger public health discussions in other large metropolitan areas. This study included over 200,000 people.

The Mexican City news was covered in various press and YouTube interviews but not widely translated in the rest of North America. Dr Vincent Mondragon explained how and when the Mexican IMSS started using ivermectin. Population health professional Juan Chamie reported to TrialSite that the IMSS was using ivermectin in the early stages of COVID. A government health plan, IMSS is used by about half of the Mexican population, and over 60 million people.

Study Research Centers/Agencies

The study was led by professionals in a number of agencies, including Mexico City Digital Agency for Public Innovation, the Mexican Social Security Institute (IMSS), and Ministry of Health Mexico City.

TrialSite notes that the IMSS helped sponsor this population-wide study across Mexico City. A governmental organization, they assist public health, pensions, and social security in Mexico operating under the Secretariat of Health and forms an integral part of the Mexican healthcare system.

The Location

Mexico City, situated in the State of Mexico, is the fifth most populated city in the world with about 22 million people. 

Summary

The Mexico City Government sponsored this innovative, population-wide initiative across Mexico City based initially on observations at Monash University Australia in April and from then on, mounting data from dozens of clinical trials and observational studies evidencing positive outcomes associated with ivermectin.  

In an effort to produce good covariate balance between exposure groups and hence lessen any impact of cofounding in observational causal inference the public health-led team employed a method known as Coarsened Exact Matching using administrative data from hospital and the comprehensive phone-call monitoring system established for purposes of this public health study. 

The study team estimated logistic-regression models with matched observations adjusting by a number of elements from COVID-19 severity and comorbidity to gender and age, etc. They separated the effect of the kit from phone medical monitoring for “robustness checks” as well as modified consumption duration and “subsetted the sample by hospitalization occupancy.”

The Mexico City study team generated compelling results in that they reduced the pressures on hospital system by 52% to 76% depending on a number of factors. These results led to the confident conclusion that this population-level, ivermectin-based intervention in fact worked well, materially lessening hospitalizations, reducing suffering and undoubtedly saving many lives.  

Lead Research/Investigator

Population Analytics

A contributor to TrialSite, Juan Chamie shared with TrialSite diagrams depicting the massively positive impact this ivermectin-based public health study has, in fact, had on Mexico City. See the diagrams below.


Call to ActionTrialSite asks a question to the TrialSite Community—why wouldn’t the press in United States or Europe pick up on such a compelling story?

Source: SocArXiv Papers



TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid19; hospitalizations; ivermectin; mexico; mexicocity

1 posted on 05/17/2021 5:56:43 PM PDT by SeekAndFind
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To: Mrs. Don-o; tellw; Huskrrrr; Jane Long; Freedom'sWorthIt; Freedom56v2; BDParrish; Phx_RC; cba123; ..

Ping for your interest


2 posted on 05/17/2021 5:57:16 PM PDT by SeekAndFind
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To: SeekAndFind

Nice!


3 posted on 05/17/2021 5:57:31 PM PDT by aMorePerfectUnion (“Old wood best to burn, old wine to drink, old friends to trust, and old authors to read.” )
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To: Jane Long

IBDTGS


4 posted on 05/17/2021 5:58:01 PM PDT by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: SeekAndFind
"Mexican covid is different than Merkun covid"

 face with tears of joy face with tears of joy face with tears of joy face with tears of joy

5 posted on 05/17/2021 5:59:50 PM PDT by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: SeekAndFind

I believe you can get HCQ over the counter in Mexican pharmacies.


6 posted on 05/17/2021 6:01:40 PM PDT by Roman_War_Criminal (Jesus + Something = Nothing ; Jesus + Nothing = Everything )
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To: SeekAndFind

The epidemiological data are hard to argue with.

This keeps happening wherever ivm is widely distributed.

The only remaining question is “how effective is it”, rather than “is it effective at all”.


7 posted on 05/17/2021 6:05:14 PM PDT by absalom01 (You should do your duty in all things. You cannot do more, and you should never wish to do less.)
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To: absalom01

“This keeps happening wherever ivm is widely distributed.”

India went back to Ivermectin after having been talked out of its continued use when Biden came in and instead to ‘trust the science’ while awaiting a vaccine.

So their cases skyrocketed and they decided that they didn’t have the luxury of the West, which was do nothing while waiting for a vaccine, so they went back to Ivermectin at the beginning of the month, and they’re back on a nice downward slope towards their prior very low numbers.


8 posted on 05/17/2021 6:22:41 PM PDT by BobL (I shop at Walmart and eat at McDonald's, I just don't tell anyone, like most here.)
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To: BobL

I’m aware that Uttar Pradesh and Goa have begun mass distribution, but not any other states in India.

In Mexico, Chiapas is still the only state with an ivm distribution scheme, and the same thing happened there.

The only way to describe the behavior of the WHO and NIH on this is “criminal”. The world still looks to those two groups for guidance, and the results speak for themselves.


9 posted on 05/17/2021 6:31:07 PM PDT by absalom01 (You should do your duty in all things. You cannot do more, and you should never wish to do less.)
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To: kiryandil

This invalidates the EUA for all the vaccines.


10 posted on 05/17/2021 6:44:14 PM PDT by Triple (Socialism denies people the right to the fruits of their labor, and is as abhorrent as slavery)
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To: Triple
This invalidates the EUA for all the vaccines.

Right.

Unfortunately, The Fantasy World of America's Left will motor on...

11 posted on 05/17/2021 6:45:41 PM PDT by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: SeekAndFind

Good info


12 posted on 05/17/2021 7:00:55 PM PDT by thinden
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To: Triple; kiryandil

Triple wrote:

“This invalidates the EUA for all the vaccines.”

Also negates the shot mandates and shot passports.


13 posted on 05/17/2021 7:14:38 PM PDT by WildHighlander57 ((WildHighlander57 returning after lurking since 2000))
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To: kiryandil

You know, in some parts of Mexico the only health care available is Rosie's hot tamale.
And I'm tellin' ya, folks, it ain't bad!

14 posted on 05/17/2021 7:16:04 PM PDT by TigersEye (Will the Younger Dryas Impact you? )
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To: SeekAndFind

Are the pharmacies in Juarez carrying this in their inventory?


15 posted on 05/17/2021 7:17:52 PM PDT by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
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To: SeekAndFind

Excellent, but sad that Mexico is ahead of the US in protecting citizens.


16 posted on 05/17/2021 8:51:24 PM PDT by WhattheDickens? (Funny, I didn’t think this was 1984…)
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To: SeekAndFind

Amazing this thread has 15 replies and this vaccine thread has 400;

https://freerepublic.com/focus/f-news/3959777/posts


17 posted on 05/18/2021 5:23:49 AM PDT by dynoman (Objectivity is the essence of intelligence. - Marilyn vos Savant)
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