Posted on 07/24/2020 6:20:46 AM PDT by daniel1212
Recent scientific studies have raised concerns and generated headlines after they suggested that antibodies to the coronavirus fade within months. But scientists say the story is more complicated — and less depressing than it seems....
Scott Hensley, a virologist at the University of Pennsylvania, tweeted that a contraction of the immune system after viral infection is “basic immunology.” Shane Crotty, a virologist at the La Jolla Institute for Immunology, told The Atlantic, “It’s not unusual to have fading antibody response after several months.”
“The drop-off isn’t that surprising. When you look at something like the smallpox vaccine, you see the antibody response is down about 75 percent after six months. But that’s a vaccine that works for decades,” Crotty said.
- Other research suggests the antibody levels decline and then stabilize. In a study of nearly 20,000 people posted to the online server MedRxiv last week, the vast majority made plentiful antibodies, and half of those with low levels still had antibodies that could destroy the virus....
“Even if you don’t have a very high level of antibodies, you may be able to respond very rapidly to a challenge and nip it in the bud — and that’s because you have memory cells that remember,” Michel Nussenzweig, head of the laboratory for molecular immunology at Rockefeller University, told the Post.
Another candidate to replace the advice of Fauci on the televised TF briefings
Until there is a readily reliable test to evaluate for T cell immunity, then there is no definitive way to determine an individual’s immunity. Also not until the susceptible genotype of people who become infected, become ill or die from this virus is defined and understood, it will be a crap shoot for anyone initially exposed.
Keep your immune system as healthy as possible. Masks, germ-free environments, no D vitamin, and isolation make it hard.
“Another candidate to replace the advice of Fauci on the televised TF briefings” that is funny.
On the serious note I see a lot of fading antibodies stories that forget to explained the T Cells functions. This is a great article.
There is still a lot we do not know about the virus and a lot of facts that are ignore too for politics on both sides.
What is ignored is that while CV-19 is real and more virulent and dangerous than the typical flu, virtually no one in good, non-overweight, active-outdoor exercise health should or does need hospital care for it or dies from it. Unlike the Asian flu of 57-58 that saw the equivalent of approx. 200,000 Americans die as a result, today 42% of the pop is obese, more suffer from hypertension, and overall the nation is in worse health. But instead of blaming this, people look to the government as if it were God, and protest due to conditions that are really mostly due to their fault.
Is this the whole article? I can’t get it at the link it want’s a sign up.
T cell immunity ( invisible immunity) seems like the most logical explanation of the virus curve that starts to burn down when the tested population shows a 25-30% covid antibody/infection pos rate.
Some researchers noted back in March that this cycle takes about 70 days to peak and decline. Michael Levitt of Stanford for example.
The cycle is similar regardless of mitigation. So lockdown or not, there is a covid active infection burnout starting at about 25% pos rate...indicating that another 40% or more of the population has active T Cell protection, making the Herd Immunity Threshold ( HIT) about 70% of the population
If this holds, FL and TX have about another 2 weeks before their infection rates start to decline
Fingers crossed
Imo the best vaccine candidates are those that induce both covid antibodies and stimulate T cell response, like this work by DR Patrick Soon-Shiong
https://twitter.com/DrPatSoonShiong/status/1280685592313884672
And yet, on our hikes in a non-mask mandate state deep in the woods we still come across about 20% mask wearers. And about 5% that make a significant effort to avoid any form of less-than-10-feet contact, to the point of running off the trail into the woods. It takes all my effort to not laugh out loud at these folks.
“If this holds, FL and TX have about another 2 weeks before their infection rates start to decline”
I think SC and GA is that peak. The population in SC are starting to social distance, I am sure this is helping too. I do remember reading those articles about peaking.
There might be another coronavirus (non-deadly type) in the wild that is generating antibodies / T-cells that helps the body to fight the Covid-19. (think cowpox / smallpox case: the vaccine is in nature already, we just need to identify it.)
If so that would explain why we did not see a lot of dying homeless people in the news. Homeless people have been expose to that other virus already. Just possible, hoping it holds true.
“Is this the whole article? I can’t get it at the link it want’s a sign up.”
It is the whole article. It took a while for the button to read more to show up. I hate it when websites do that...
Or that some people generated T Cells based on exposure to other viruses or even from prior vaccinations to TB or the MMR vaccine. Maybe another reason healthy children are able to resist infection.
Unfortunately the longer we lockdown and limit the social exposure of children and healthy adults, the more we deliberately weaken their immune systems. And far far fewer parents are taking their kids for routine healthcare that includes vaccines..which schools used to screen for.
If nature is having her way with us, regardless of our efforts to thwart her...but people believe they have control by wearing a cloth mask...then let them have their comfort. I think Trump figured this out and encouraged ( NOT ORDERED) us to go along.
The end game in the short to mid-term is reducing anxiety and fear and getting schools and businesses back in operation. Mask wearers and non mask wearers mocking each other or worse is a divisive distraction promoted by the MEdia to attack Trumpism.
ok thanks
Bookmark
“It takes all my effort to not laugh out loud at these folks.”
Spare yourself the effort, and have a good laugh.
“Is this the whole article?”
No, it is not. Load the page, close the page then reload: The “read full article” button should be evident. Some browsers might have it appear after a short time; mine did not.
On some sites you might need to clear your cache of cookies (i.e. “reached your article reading limit”).
Nonetheless, it’s a pretty useless article, other than citation of the single study on antibodies posted online last week and apparently never shared at FR (I just looked):
SARS-CoV-2 infection induces robust, neutralizing antibody responses that are stable for at least three months
https://www.medrxiv.org/content/10.1101/2020.07.14.20151126v1
No, it is about a 220 word excerpt(s) providing the gist of it, and after a few free articles, the Globe wants money. I signed up on a 1.00 special for many months, using a gift card which has no more money in it for the Globe to get when the trial runs out.
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