Posted on 02/20/2020 12:38:21 PM PST by Norski
More than 1.7 million Americans develop sepsis every year and incidence of the condition is on the rise. In severe cases, widespread inflammation leads to multiorgan failure and death. Results of a new study hold the tantalizing prospect that, for some patients with sepsis, intravenous (IV) vitamin C could increase survival and shorten intensive care unit (ICU) stays.
The findings, published in JAMA, are from the CITRIS-ALI (Vitamin C Infusion for Treatment In Sepsis-Induced Acute Lung Injury) trial. Cleveland Clinic was one of seven enrollment sites across the country chosen for the study because of the diversity of its patients and the number of cases of sepsis it sees.
Conducted from September 2014 to November 2017, CITRIS-ALI was the first randomized, double-blind, placebo-controlled multicenter trial to assess vitamin C and its potential impact on sepsis and acute respiratory distress syndrome (ARDS).
“We hypothesized that IV administration of vitamin C would lead to a decrease in inflammation, and hence, improved outcomes,” said co-author Abhijit Duggal, MD, MPH, MSC, Director of Critical Care Research. “But the organ dysfunction scores and inflammatory markers in patients who received vitamin C was not much different from that in the placebo group. However, there were significant differences in the hard outcomes of mortality and length of stay.”
(Excerpt) Read more at consultqd.clevelandclinic.org ...
“unless taken orally then it can lead to a serious need for bathroom facilities.”
Concerned about the runs while you are laying in an ICU bed dying of Sepsis while tied to all kinds of tubes and machines? Ok, no Vitamin C for you!
He’s moderated his recomendations.
The LEF foundation typically stays well south of 2000mg
“He’s moderated his recomendations.
The LEF foundation typically stays well south of 2000mg.”
Pauling’s long dead, but I don’t know that he ever moderated his recommendation for Vitamin C consumption before he passed, nor have his disciples (Mathias Rath, et al); I’d appreciate a link to that if you’ve got one. I’ve taken LEF products for as long as they’ve been in business but I don’t agree with them about everything - nor do various experts in the supplement/nootropic field.
Thank you. I take about 10,000 iu every few days.
It may be a kindness and of significant help, possibly, for this article to be re-posted very soon in a high-readership time period.
Good Idea. You have my blessing to do so.
Cytosorb. Hmm. The article certainly reads as an advertisement. Perhaps it is time to do more research.
I did attempt. Unfortunately, the magazine site does not allow non-subscribers access.
P4L
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