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A gut bacterium as a fountain of youth? Well, let’s start with reversing insulin resistance
www.orlandosentinel.com ^ | 11/15/2018 | Melissa Healy

Posted on 11/16/2018 11:17:28 AM PST by Red Badger

Move over Bifidobacterium and Lactobacillus. There’s a new health-promoting gut bacterium in town, and it’s called Akkermansia muciniphila.

You will not find its benefits at the bottom of a yogurt cup. But a new study has identified more than one way to nurture its growth in the gut, and offered evidence that it may maintain — and even restore — health as we age.

Published this week in the journal Science Translational Medicine, the new research found that in mice and monkeys whose metabolisms had grown cranky with age, taking steps to boost A. muciniphila in the gut reduced the animals’ insulin resistance.

Insulin resistance is the gradual impairment of the body’s ability to efficiently use food for fuel. It is best known as a way station on a patient’s path to developing type 2 diabetes.

But insulin resistance is also linked to a rogue’s gallery of ills, from obesity and inflammation to the sagging immunity and frailty that comes with advancing age. If a readily available means of slowing or reversing insulin resistance could be identified, it might have broad and powerful anti-aging effects (in addition to protecting some of the world’s 650 million adults who are obese against developing type 2 diabetes).

First identified in 2004, Akkermansia muciniphila inhabits the large intestine and is thought to account for between 1% and 5% of all intestinal bacteria in adults. Scientists suspect it helps preserve the coat of mucus that lines the walls of our intestines. It may also play a role in making the polyphenols we eat in plant-based foods more available to our cells.

Evidence is mounting that A. muciniphila is involved in obesity, glucose metabolism and intestinal immunity.

(Excerpt) Read more at orlandosentinel.com ...


TOPICS: Agriculture; Food; Health/Medicine; Science
KEYWORDS:
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1 posted on 11/16/2018 11:17:28 AM PST by Red Badger
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To: Red Badger

Executive summary.


2 posted on 11/16/2018 11:25:50 AM PST by 2ndDivisionVet (You cannot invade the mainland US. There'd be a rifle behind every blade of grass.)
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To: 2ndDivisionVet

As requested

An A. muciniphila deficit in the large intestine is not good for your health


3 posted on 11/16/2018 11:31:24 AM PST by bert ((KE. N.P. N.C. +12) Invade Honduras. Provide a military government)
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To: Red Badger

Stop eating bread

Live on eggs and ilk and cheese and veggies and meat (not processed) for a month and see what happens

DO NOT buy expensive (and hideous) ‘gluten free’ foods from the store. Just stop eating bread and noodles and anything wheat for a month.

I snack on cottage cheese with peaches, pepperoni and cheese, dark chocolate, and have lost 20 pounds so far


4 posted on 11/16/2018 11:37:00 AM PST by Mr. K (No consequence of repealing Obamacare is worse than Obamacare itself.)
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To: bert

How does one acquire said bacteria?


5 posted on 11/16/2018 11:38:13 AM PST by 2ndDivisionVet (You cannot invade the mainland US. There'd be a rifle behind every blade of grass.)
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To: Red Badger

Note: The bunch that puts out this journal is all in on climate change. Trust but verify.


6 posted on 11/16/2018 11:39:12 AM PST by mewzilla (Is Central America emptying its prisons?)
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To: Mr. K

Better yet...carb-free.

I cheat; sugar is metabolized almost immediately so I snack on chocolate thru-out the day but never between dinner and bed. Also, fiber is classified as a carbohydrate but I don’t and eat as much as I want.

All the protein, fat and veggies you can eat!


7 posted on 11/16/2018 11:42:00 AM PST by Cletus.D.Yokel (Catastrophic, Anthropogenic Climate Alterations: The acronym explains the science.)
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To: Mr. K

What about pasta? Take away my mac & cheese? As Charlton Heston might say, “From my cold, dead hands!”


8 posted on 11/16/2018 11:42:46 AM PST by irishjuggler
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To: Red Badger

Or... people could exercise. But, nope, we want to pop a pill, sit on the couch and eat a gourmet meal every time we feel a twinge of hunger. And then we wonder why diabetes is going off the charts and obesity is rampant in society.


9 posted on 11/16/2018 11:43:51 AM PST by Obadiah
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To: 2ndDivisionVet

Looking at the article.

Consuming Butyrate, available online will boost levels.


10 posted on 11/16/2018 11:45:16 AM PST by DannyTN
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To: 2ndDivisionVet

Looking at the article.

Consuming Butyrate, available online will boost levels.


11 posted on 11/16/2018 11:45:16 AM PST by DannyTN
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To: Mr. K

chocolate is a health food!....................


12 posted on 11/16/2018 11:46:21 AM PST by Red Badger (We are headed for a Civil War. It won't be nice like the last one....................)
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To: bert

I know someone with n Akermansia in their gut. They have both MS & RA.


13 posted on 11/16/2018 11:51:30 AM PST by meatloaf
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To: DannyTN

Butyric acid has a nasty odor. Is this stuff sufficiently different so as to avoid that problem?


14 posted on 11/16/2018 11:52:14 AM PST by Fresh Wind (Trump: "In the meantime, I'm president and you're not!")
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To: Red Badger
"First identified in 2004, Akkermansia muciniphila inhabits the large intestine and is thought to account for between 1% and 5% of all intestinal bacteria in adults."

Sounds like it won't belong before cultures of A. muciniphila start showing up on shelves.

What has been learned about the human gut in the last 20 years is really amazing. Our gut microbiota contains tens of trillions of microorganisms, including at least 1,000 different species of known bacteria with more than 3 million genes (150 times more than human genes), but only 150 to 170 predominate in any given individual. Microbiota can, in total, weigh up to 4.5 pounds. One third of our gut microbiota is common to most people, while two thirds are specific to each one of us. In other words, the microbiota in your intestine is like an individual identity card.

So Akkermansia muciniphila in our guts weighs 0.7 ounces to 3.5 ounces in total and we didn't know about it until 2004!

In a similar vein,Helicobacter pylori the a bacterium that colonizes human stomach and causes of chronic superficial gastritis, chronic active gastritis, peptic ulcer disease and gastric adenocarcinoma was first identified in 1985. H. pylori is now recognized causes more than 90% of duodenal ulcers and up to 80% of gastric ulcers. I had H. pylori for years and my doctor could not figure out my stomach symptoms. Finally, after doing my own research, I got after my doctor to test for it and it came back positive. One regimen of antibiotics eradicated it in early 2018 and I feel so much better than I have in years.

15 posted on 11/16/2018 11:55:34 AM PST by ProtectOurFreedom
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To: irishjuggler

It’s up to you

If you have a big fat bloated gut, continue eating all that crap

I have totally lost my appetite for anything like that since going gluten-free

It used to be I would eat it by the bucketful- I’ve eaten a whole box full, AND made a second... before thinking that I had to stop that.

The biggest change since going gluten-free is that I am NOT hungry all the time any more. I used to eat all day and still be starving- it turns out the wheat block absorption of nutrients from your food- so you eat like crazy but get nothing out of it but the fat.

Some days I forget to eat- I am just not hungry all the time any more.


16 posted on 11/16/2018 11:58:43 AM PST by Mr. K (No consequence of repealing Obamacare is worse than Obamacare itself.)
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To: Red Badger
... the new research found that in mice and monkeys whose metabolisms had grown cranky with age, taking steps to boost A. muciniphila in the gut reduced the animals’ insulin resistance.

Can't tell you how many tests using mice and monkeys fail to produce the same outcome in humans.

It would be interesting to see the results of double blind studies with humans with this supposed super bacterium.

17 posted on 11/16/2018 12:12:11 PM PST by JesusIsLord
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To: 2ndDivisionVet
“How does one acquire said bacteria?” Trust me, you don’t want to know. 😉
18 posted on 11/16/2018 12:17:51 PM PST by semaj (We are the People)
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To: DannyTN

bkmk


19 posted on 11/16/2018 12:20:56 PM PST by Sergio (An object at rest cannot be stopped! - The Evil Midnight Bomber What Bombs at Midnight)
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To: bert

The probiotic I use doesn’t have that listed on the label-but it does appear to contain every other beneficial strain of probiotic stuff-is there a probiotic that contains it?


20 posted on 11/16/2018 12:22:52 PM PST by Texan5 ("You've got to saddle up your boys, you've got to draw a hard line"...)
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