Posted on 02/26/2024 9:11:17 PM PST by ConservativeMind
Research suggests that the gut microbiome plays a pivotal role in the development of chronic obstructive pulmonary disease (COPD), paving the way for new therapeutic treatments.
Key discoveries include the identification of distinct gut bacteria associated with COPD and the potential effectiveness of fecal microbiota transfer (FMT) as a COPD treatment. The study also demonstrated improved outcomes for COPD patients through nutritional interventions tailored to the microorganisms found in the gut.
"The gut hosts the largest and most diverse microbiome in the body that, depending upon its composition, can either trigger or inhibit inflammation, including in the lung," said Professor Phil Hansbro.
"We were able to identify specific gut bacteria associated with the development of COPD in our mouse models, confirming the complex interplay between the gastrointestinal microbiome, inflammation, and lung disease," he said.
Professor Hansbro added that the study had also demonstrated the potential effectiveness of fecal microbiota transfer (FMT) in the treatment of COPD.
"We used FMT to transfer beneficial gut microorganisms between healthy and COPD mice, which helped to reduce lung inflammation and improve breathing. This suggests a potential therapeutic effect of these specific gut microbes in mitigating COPD-related issues," said Professor Hansbro.
Dr. Kurtis Budden highlighted positive outcomes for COPD patients resulting from dietary interventions.
"Enhancing the diet of a small select group of human COPD patients through dietary fiber supplementation led to noticeable improvements in disease symptoms. Likewise, providing a high-resistant starch diet to mice with COPD yielded beneficial outcomes. These discoveries point towards a promising direction for dietary modification in the management of COPD," said Dr. Budden.
The researchers state that their work opens up exciting new possibilities for microbiome-targeting treatments that could make a real difference in the lives of people dealing with COPD—a disease for which there is currently no cure.
(Excerpt) Read more at medicalxpress.com ...
“Disease features correlated with the relative abundance of Muribaculaceae, Desulfovibrionaceae and Lachnospiraceae family members. Proteomics and metabolomics identified downregulation of glucose and starch metabolism in CS-associated microbiota, and supplementation of mice or human patients with complex carbohydrates improved disease outcomes.“
These cultures are not included in probiotic supplements or yogurts. However, we normally carry these, and appear to be able to encourage their growth with complex carbohydrates and soluble fiber.
Of course, fecal transfers also work, they found.
I actually discovered this myself.
I had a terrible problem with bloating, COPD and acid reflux.
I tried several different probiotics, but to no avail.
Then I tried a delayed release probiotic and after one day I was cured.
This one is good too.
Been six months now, and I have never had a relapse.
I highly recommend raw sauerkraut as a source of probiotics. It’s fairly inexpensive and it’s worked wonders for me. Don’t buy the pasteurized sauerkraut because all the beneficial probiotics are dead.
Thanks for the info
I might have to start with an amateur biotic 😜
Save some money 💰
Even 10 years ago, very few people outside of medical research understood the intimate relationship between the microbes in your intestines and your brain health and general health.
Even though I have been reading medical information every week for 60 years, I am still a little shocked by this particular development.
I’m on daily time release Omeprazole now. I’d love to stop. Would you guess the one of these Probiotics would do the job? (Although my prescription is MUCH less than these because of insurance, I can’t imagine Omeprazole is good for you overall.)
Is this gluten-free issue something new like peanut allergies, or has it been around forever?
It's worth a try. It worked for me the first day. I was astonished because I had been in severe distress for months. I could only sleep sitting up. When I lay down I would have reflux within a couple of minutes.
I think my stomach problems started when I took amoxicillin when I had the Chinese flu and my gut flora got decimated. The key is a probiotic with delayed release. Without it, the microorganisms get killed by your stomach acid before they reach your small intestine.
This one is cheaper than Align and has a larger variety of microorganisms.
I think there are smaller, cheaper packages. Once you get the right bacilli in your stomach they will reproduce on their own. If it works the first day like it did for me, you probably won't need to take any more, but you might as well take them every day until you run out. That's what I did.
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Thank you!
I had regular reflux. Ate less, stopped eating late, and occasionally drank something acidic like apple cider vinegar, or maybe lemon juice diluted in some water about 1 1/2 hours before bedtime. I think I have only had one recent episode, and that was from eating before bed.
I hope what you are doing keeps working.
A link to fermented foods. (Search turns up a lot of "how to" fermenting sites. )
https://draxe.com/nutrition/fermented-foods/
Thank you, thank you!!! I’ll go to Walmart tomorrow and get the Align and see if it works for me. I’ve had all 3 problems for years hopefully this will work for me.
bfl
Did you try it? Did it work?
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