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Human-mouse HYBRID: Scientists grow human brain in tiny rodent
www.express.co.uk ^ | 04/19/2018 | By Sean Martin

Posted on 04/19/2018 10:37:13 AM PDT by Red Badger

SCIENTISTS have controversially yet successfully grown part of a human brain inside a mouse and the organ even managed to survive for months in a major scientific breakthrough. ____________________________________________________________________________________________________________

For the first ever time miniature human brains have grown in a new species and scientists have suggested the breakthrough could help with stem cell research.

Scientists created the pin-sized human brains from stem cells and then placed them inside the skulls of mice, where a piece of tissue had been removed to make room for the new organ.

Of the test mice, roughly 80 percent survived the operation, and within two weeks the rodents’ implants had been successfully received and were even spawning new neurons.

The brain implants survived for an average of 233 days, but began the process of dying much earlier.

Lead researcher Fred Gage, a neuroscientist at the Salk Institute, said: "In our hands, the organoids stop growing around five weeks.

"It's a function of size rather than time. We see some cell death even in the edge of the organoids starting at 10 weeks, which becomes really dramatic over time.

“This is an obvious hurdle for longtime study."

Abed Al-Fattah Mansour, a research associate at the Salk Institute, said: "That was a big accomplishment.

“We saw infiltration of blood vessels into the organoid and supplying it with blood, which was exciting because it's perhaps the ticket for organoids' long-term survival.”

In this exercise, the scientists accomplished three things – installing an organoid into a complex tissue environment, connecting it to the species and integrating it into the cardiovascular system of the organism.

The researchers say the breakthrough could one day help with repairing organs such as brains from stem cells.

Mr Mansour added: “These three elements are important for both basic research and drug discovery of brain disorders; for example, our approach has the potential for pre-clinical drug testing of patient-specific derived brain organoids under the organism setup.

"In addition, long-term survival could help the organoid to develop beyond the present embryonic stages that we see in culture.

"We hope this technology will set the stage and help to understand the pathogenesis of neurodevelopmental, neuropsychiatric and neurodegenerative disorders by enabling the generation of brain organoids from patients' own stem cells, transplanted into rodents.”


TOPICS: Education; Health/Medicine; Pets/Animals; Society
KEYWORDS: brain; brainresearch; stemcells
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To: Red Badger
I wonder if it's first thought was to buy land in Anaheim?

-PJ

21 posted on 04/19/2018 11:02:01 AM PDT by Political Junkie Too (The 1st Amendment gives the People the right to a free press, not CNN the right to the 1st question.)
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To: Red Badger

as if the little bastids aren’t clever enough the way it is...


22 posted on 04/19/2018 11:09:06 AM PDT by bigbob
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To: Red Badger

The Rats of NIHM


23 posted on 04/19/2018 11:10:55 AM PDT by Mercat
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To: Red Badger
Image result for mouse smart gif
24 posted on 04/19/2018 11:15:25 AM PDT by ETL (Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Nukes. See my FR home page)
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To: Red Badger
Image result for mouse thief gif
25 posted on 04/19/2018 11:17:06 AM PDT by ETL (Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Nukes. See my FR home page)
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To: Red Badger
Related image
26 posted on 04/19/2018 11:18:16 AM PDT by ETL (Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Nukes. See my FR home page)
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Related image
27 posted on 04/19/2018 11:20:13 AM PDT by ETL (Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Nukes. See my FR home page)
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To: Red Badger

Forget “Planet of the Apes” Prepare instead for “Planet of the Mice.”


28 posted on 04/19/2018 11:22:09 AM PDT by from occupied ga (Your government is your most dangerous enemy)
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To: Sacajaweau

Sorry....this is sick...


Making my stomach turn...how horrific!


29 posted on 04/19/2018 11:23:37 AM PDT by DefeatCorruption
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To: Red Badger

Mixed-up posts on the cutting room floor:

“Human-mouse HYBRID: Scientists grow human brain in tiny rodent for Pizza Rat 1, Mayor de Blasio 0

New York City Mayor Bill de Blasio is on a campaign to wipe
out the large populations of rats that plague the city and,
to replace them with rats with human brains. This will get
the brainy rats out of the sewers and into the housing projects,which aren`t that much better than the sewers,
“But what the hell! We gotta do something!” said de Blasio.
This will allow for a 1,000,000 percent increase in more
space available in the housing projects


30 posted on 04/19/2018 11:28:57 AM PDT by bunkerhill7 ((((("The Second Amendment has no limits on firepower"-NY State Senator Kathleen A. Marchione.")))))))
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To: Red Badger

They are working hard and burning the midnight oil on these experiments, because ... why? Does Apollyon need a hand producing minions? Revelation 9:7-11 :

The locusts looked like horses prepared for battle. On their heads they wore something like crowns of gold, and their faces resembled human faces. Their hair was like women’s hair, and their teeth were like lions’ teeth. They had breastplates like breastplates of iron, and the sound of their wings was like the thundering of many horses and chariots rushing into battle. They had tails with stingers, like scorpions, and in their tails they had power to torment people for five months. They had as king over them the angel of the Abyss, whose name in Hebrew is Abaddon and in Greek is Apollyon (that is, Destroyer).

31 posted on 04/19/2018 11:31:26 AM PDT by so_real ( "The Congress of the United States recommends and approves the Holy Bible for use in all schools.")
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To: bunkerhill7

To defeat a rat, first you must be smarter than the rat.....................


32 posted on 04/19/2018 11:31:45 AM PDT by Red Badger (Remember all the great work Obama did for the black community?.............. Me neither.)
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To: Red Badger

Story from 18 years ago. Named it David Hogg.


33 posted on 04/19/2018 11:59:29 AM PDT by StAntKnee (Add your own danged sarc tag)
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To: Red Badger
Deblasio couldn't have picked a worse time to try to eradicate rats today. He wants to get rid of them now they can host human

Looks like these NY idiots could use a rat brain as they look clueless.

34 posted on 04/19/2018 12:01:45 PM PDT by Blue Highway
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To: Blue Highway
He wants to get rid of them, the very day they find out they can host human demoRAT brains.
35 posted on 04/19/2018 12:03:19 PM PDT by Blue Highway
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To: Red Badger

Of course...will be therapeutic at first....but then....can you imagine a soldier with the strength of a large chimp...and a devious mind of a human..or a group of jaguars with the pack mentality and ferociousness of a pit bull..
We’ll be totally safe with no guns....maybe they will eat the feral Hoggs.


36 posted on 04/19/2018 12:10:28 PM PDT by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: Sacajaweau

“Sorry....this is sick...”

Sounds like ‘just because we can’.


37 posted on 04/19/2018 12:19:00 PM PDT by dljordan (WhoVoltaire: "To find out who rules over you, simply find out who you are not allowed to criticize.")
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To: Red Badger

That explains it. I guess something went terribly wrong.

38 posted on 04/19/2018 12:24:15 PM PDT by seawolf101 (Member LES DEPLORABLES)
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To: BBell

My first thought as well. Eek, a mouse!


39 posted on 04/19/2018 12:31:47 PM PDT by Mr. Blond
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To: Sacajaweau

These brain organoids are very small and not conscious, but they create enough differentiated tissue to allow for the study of human brain diseases that were not possible before.

Adult stem cells are used, usually from the skin. Whatever happened to embryonic stem cells? Remember what a stink corrupt Democrats and crooked journalists made about them?


40 posted on 04/19/2018 12:49:30 PM PDT by Moonman62 (Give a man a fish and he'll be a Democrat. Teach a man to fish and he'll be a responsible citizen.)
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