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Data About Zetia Risks Was Not Fully Revealed
NY Times ^ | December 21, 2007 | ALEX BERENSON

Posted on 12/22/2007 2:30:45 AM PST by neverdem

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1 posted on 12/22/2007 2:30:49 AM PST by neverdem
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Everyday Items, Complex Chemistry

Scientists Weigh Stem Cells’ Role as Cancer Cause

FReepmail me if you want on or off my health and science ping list.

2 posted on 12/22/2007 2:53:48 AM PST by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: neverdem

“Zetia’s potential to cause hepatitis, pancreatitis and depression”

Statin drugs are not worth the risk, especially when you consider that they don’t even bring down cholesterol that much.

The link between heart disease and cholesterol is based on a flawed study back in the 50’s or 60’s. The long-term Framingham study has found just the opposite to be true.


3 posted on 12/22/2007 3:56:05 AM PST by webstersII
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To: neverdem

Thanks for the ping. My husband takes Vytorin, time for a doctor’s appointment and questions I think.


4 posted on 12/22/2007 3:59:17 AM PST by Duchess47 ("One day I will leave this world and dream myself to Reality" Crazy Horse)
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To: neverdem
The companies’ own published studies have generally played down the risk of liver problems. But Dr. Mark Stolk, a gastroenterologist in the Netherlands, last year reported two cases of patients who had developed hepatitis, a liver disease, after taking Zetia alongside Lipitor.

This does not look like good Science. Statins are known to disrupt certain liver functions, and people taking them are thus routinely tested. Evaluating Zetia in patients taking it in combination with a statin is multiplying variables. Zetia may potentiate the effects, though, both good and bad.

Data is needed for Zetia alone, first.

5 posted on 12/22/2007 4:04:52 AM PST by Gorzaloon
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To: webstersII
The link between heart disease and cholesterol is based on a flawed study back in the 50’s or 60’s. The long-term Framingham study has found just the opposite to be true.

Do you mean that high cholesterol is a good thing?

6 posted on 12/22/2007 4:07:13 AM PST by Glenn (Free Venezuela!)
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To: Glenn
"Do you mean that high cholesterol is a good thing?"

Did I say that? Of course not.

Cholesterol is important in brain function, which explains why one of the possible side effects of statin usage is dementia. When you throw in possible symptoms of neuropathy, liver disease, fatigue, and a host of other potential problems, you have to ask whether the statin "cure" is worse than the disease.

Link

"Dr. Uffe Ravnskov, MD, PhD, who wrote the book The Cholesterol Myths, goes through study after study destroying the idea that high cholesterol levels are the cause of heart disease. In the Framingham heart study done near Boston that spanned 30 years , the researchers concluded that high cholesterol was a risk factor for heart disease, but when one really dissects the data, one must question how they came to that conclusion. For example, when the participants of the study are plotted on a graph it clearly shows that those with cholesterol levels between 182 and 222 did not survive as long as those with higher cholesterol levels of between 222 and 261. The study shows that about half the people with heart disease had low cholesterol, and half the people without heart disease had high cholesterol."

The issue with heart disease is not cholesterol but inflammation. That's why statins seem to improve deaths from heart disease -- not because lower cholesterol prevents heart disease but the statin's ability to reduce inflammation in the blood vessels.

Statin drugs are a lousy way to lower inflammation (which can be measured by blood tests). Changes in lifestyle -- nutrition and appropriate supplementation -- to lower inflammation markers don't have the nasty side effects that statins do.

There is a wealth of info out there on cholesterol and heart disease. If you get away from the pharmaceutical industry-funded websites or other sites with built-in bias of selling a product you can find good data.

7 posted on 12/22/2007 4:36:01 AM PST by webstersII
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To: neverdem

Thanks for the post. I started on Zetia about 2 months ago because I didn’t want to take Lipitor. I know two people on that with messed up livers because of it. I’m going to call my doctor first thing Monday and stop taking this crap.


8 posted on 12/22/2007 4:36:10 AM PST by usconservative (www.ropma.net -->ISLAM a religion of peace? (Mr. President, you're nuts if you believe it!))
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To: webstersII
When you throw in possible symptoms of neuropathy, liver disease, fatigue, and a host of other potential problems, you have to ask whether the statin "cure" is worse than the disease.

My heart doc is one of the brightest people on the planet. I trust him without reserve. He explained the risks/rewards of statins and I take the pills. They haven't killed me yet and I'm no longer symptomatic.

9 posted on 12/22/2007 4:41:38 AM PST by Glenn (Free Venezuela!)
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To: usconservative

>>>Thanks for the post. I started on Zetia about 2 months ago because I didn’t want to take Lipitor. I know two people on that with messed up livers because of it. I’m going to call my doctor first thing Monday and stop taking this crap.

I nearly died in April ‘06 from necrotic pancreatitis that they say was gall stone induced....but I’ve been on Zetia too, and now wonder if it played a role....Hmmmm...


10 posted on 12/22/2007 4:49:10 AM PST by Keith in Iowa (Life's a bitch, don't elect one President.)
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To: usconservative

www.curezone.com is a great website. Read it before starting drugs.


11 posted on 12/22/2007 5:01:36 AM PST by Conservativegreatgrandma
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To: Glenn

“My heart doc is one of the brightest people on the planet.”

Really? I wonder if he knows that heart disease is not caused by cholesterol and that statin drugs only help heart disease patients by reducing inflammation.

Statins are a still risky way to reduce inflammation compared to the alternatives.


12 posted on 12/22/2007 5:15:17 AM PST by webstersII
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To: webstersII
I wonder if he knows that heart disease is not caused by cholesterol and that statin drugs only help heart disease patients by reducing inflammation.

I'll be sure and tell him you disagree. I'm sure he'll defer instantly.

13 posted on 12/22/2007 5:19:44 AM PST by Glenn (Free Venezuela!)
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To: neverdem

All these cholesterol drugs have consequences.
I was taking Zetia and Lipitor until my feet hurt so bad I could hardly walk. I cut out the Zetia myself.
These drugs do 2 things, lower cholesterol and make it so that healing from anything takes a long long time. I learned, about 5 years ago, that if I get a cold or flu, or I get cut or bruised, I need to stop these meds or it will take forever to get better. If I get a cut on my hand while working around the house, for instance, 3 to 4 months to heal while taking statins or stop the statins and heal in 1 to 2 weeks.
I wonder what else they are doing to me.


14 posted on 12/22/2007 5:27:33 AM PST by BuffaloJack (Before the government can give you a dollar it must first take it from another American)
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To: Glenn

“I’ll be sure and tell him you disagree. I’m sure he’ll defer instantly.”

We all put our trust in whatever or whomever we choose.


15 posted on 12/22/2007 5:40:46 AM PST by webstersII
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To: BuffaloJack

“I was taking Zetia and Lipitor until my feet hurt so bad I could hardly walk. I cut out the Zetia myself.”

I have a relative that had the same issue. But the doctor gave her something else for her foot pain, and then something else for the side effects from that. . . . .

These things can be a never-ending cycle. But I didn’t realize that they impaired immune system and tissue repair. That’s a very serious side effect.


16 posted on 12/22/2007 5:44:07 AM PST by webstersII
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To: neverdem

What I want to know is this, will it make them stop broadcasting those horrid commercials?


17 posted on 12/22/2007 6:02:36 AM PST by NonValueAdded (Fred Dalton Thompson for President)
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To: NonValueAdded

“What I want to know is this, will it make them stop broadcasting those horrid commercials?”

Only if the payouts to the injured parties get high enough.


18 posted on 12/22/2007 6:35:47 AM PST by webstersII
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To: webstersII

“The study shows that about half the people with heart disease had low cholesterol, and half the people without heart disease had high cholesterol.” “

that is the truth - there is absolutely no correlation between serum cholesterol and heart disease.

you are right re: inflamation and thats why aspirin is so good as is good dental care and avoidance of all low level infections like ulcers and i think even acne.


19 posted on 12/22/2007 6:41:20 AM PST by spanalot (*)
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To: Duchess47; neverdem
Vytorin....I know about that one...

I couldn't handle the muscle pain and weakness taking it daily...

Doctor is now trying it on me with dosage of twice a week....

Will see how that goes soon.

20 posted on 12/22/2007 6:55:19 AM PST by Ernest_at_the_Beach (No Burkas for my Grandaughters!)
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