C'mere and let mommy kiss your boo boo!
Posted on 11/13/2006 3:12:44 PM PST by blam
When I was in college and had my own lab rat (Rat Fink), I was surprised to learn that Purina made "Purina Rat Chow." I learned something new every semester.
I think so too, no spoof, and was just about to write to say so, but noticed you got there first. If not an antibiotic, SOMETHING that heals. A friend's dad pointed it out when we were kids. My family didn't have a dog so I thought that was neat.
C'mere and let mommy kiss your boo boo!
I've noticed you've been rather pale. Have you looked at yourself in a mirror lately?
LOL! That was great :-).
OUCH! My eyes hurt now; spit, spit, rub, rub. There. Now all better. Oh no there she is again . . . ARRRRGH!!!! Blinded.
Ping
Yeh, sure, as if they knew. And when they were throwing sack of feces at them... they were just trying to remind them of their dog back home. Riiight. :)
hmmmm ....
Mammalian zinc ectopeptidases play important roles in turning off neural and hormonal peptide signals at the cell surface, notably those processing sensory information.
We report here the discovery of a previously uncharacterized physiological inhibitor of enkephalin-inactivating zinc ectopeptidases in humans, which we have named Opiorphin.
It is a QRFSR peptide that inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11), and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2).
Opiorphin displays potent analgesic activity in chemical and mechanical pain models by activating endogenous opioid-dependent transmission. Its function is closely related to the rat sialorphin peptide, which is an inhibitor of pain perception and acts by potentiating endogenous µ- and {delta}-opioid receptor-dependent enkephalinergic pathways.
Here we demonstrate the functional specificity in vivo of human Opiorphin. The pain-suppressive potency of Opiorphin is as effective as morphine in the behavioral rat model of acute mechanical pain, the pin-pain test.
Thus, our discovery of Opiorphin is extremely exciting from a physiological point of view in the context of endogenous opioidergic pathways, notably in modulating mood-related states and pain sensation.
Furthermore, because of its in vivo properties, Opiorphin may have therapeutic implications.
Could be. It seems to be one of the few instinctive behaviors humans have. (Flirting behaviors are pretty universal across cultures too).
My Mom always complained, an admiring sort of complaint, that Dad never got seriously hurt or sick. When he'd get a cut or abrasion, he'd just stick it in his mouth or lick it, then leave it alone. He never got gangrene or tetanus or anything like that. Until the cancer, the only time he was in the hospital was when he got a piece of metal in his eye, at least I think he spent some time in the hospital with that, it was before my time. Once the dang doctors diagnosed the colon cancer, it only runs in his family and the symptoms were pretty obvious, he beat that too, with surgery and a little chemo. He lived over 10 years after that. Then the Alzheimer's kicked in... that runs in the family too. Pneumonia in the "home" finally got him, mercifully after only three weeks in that place that he hated.
Double-hmmmmmmmmm....
Thanks for the *ping*!
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.