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Keyword: thalidomide

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  • Thalidomide teams-up with turmeric to kill myeloma cells

    07/02/2013 8:00:41 PM PDT · by neverdem · 53 replies
    Chemistry World ^ | 2 July 2013 | Sonja Hampel
    One of the curcumin–thalidomide hybridsCancer researchers in the US and China have combined the turmeric spice pigment curcumin and the drug thalidomide to create hybrid compounds that can kill multiple myeloma cells.Multiple myeloma is the second most common type of blood cancer, killing 20% of affected patients each year. The drug thalidomide, banned after causing birth defects when given during pregnancy in the 1950s, was recently rediscovered and approved for the treatment of multiple myeloma. Thalidomide works by disturbing the microenvironment of tumour cells in bone marrow. However, it disintegrates in the body. Curcumin, a yellow pigment from the common...
  • Australian woman wins multi-million Thalidomide payout from Diageo

    07/18/2012 12:00:26 AM PDT · by Olog-hai · 5 replies
    Reuters ^ | Wed Jul 18, 2012 2:36am EDT | (Reporting by Aicha Marhfour; Editing by Daniel Magnowski)
    An Australian woman has won a multi-million dollar payout from UK company Diageo PLC, the local distributor of the drug Thalidomide that caused birth defects in thousand of babies around the world in the 1960s, her lawyers said on Wednesday. Lynette Rowe, 50, was born without arms and legs after her mother Wendy took Thalidomide for a month while pregnant. At the time the drug was prescribed as a treatment for morning sickness. The settlement with Rowe could pave the way for more than 100 other Thalidomide victims in Australia and New Zealand to receive compensation through a class action,...
  • How thalidomide makes its mark

    05/12/2009 3:41:54 PM PDT · by neverdem · 5 replies · 521+ views
    Nature News ^ | 11 May 2009 | Heidi Ledford
    Drug's effects on embryonic blood-vessel growth may be the source of malformed limbs. Thalidomide's effect on growing blood vessels may have caused birth defects in thousands of children.National Cancer Institute More than 50 years after the drug thalidomide hit the market as a remedy for nausea in pregnant women, researchers may finally have pinned down how it causes severe birth defects. Their results show that the drug's ability to block the development of new blood vessels may be behind the deformed limbs of children born to women who took thalidomide early in pregnancy. The finding could contribute to the development...
  • Thalidomide? What's all the fuss? [Inspirational story]

    07/08/2008 5:36:55 PM PDT · by Alouette · 3 replies · 110+ views
    Daily Mail UK ^ | July 8, 2008 | Tricia Welch
    It's 50 years since Thalidomide was first prescribed to pregnant women suffering from morning sickness. It was then found that the drug caused serious birth defects: 500 babies suffered varying degrees of disability as a result. Here, three generations of women tell their story. June Hornsby, 71, has six children with her husband Len, 76. Their daughter Mandy was born in 1962 with no arms.
  • A Transcendent Voice (How a German thalidomide baby became one of the world’s greatest singers)

    10/01/2006 12:22:52 PM PDT · by paulat · 19 replies · 1,403+ views
    The New York Times Magazine ^ | 10/1/06 | Arthur Lubow
    A Transcendent Voice By ARTHUR LUBOW Thomas Quasthoff titled both his autobiography and a recent CD compilation “The Voice,” underscoring the bass-baritone vocal instrument that has made him an internationally acclaimed singer. But it is safe to say that the main thing an audience notices when Quasthoff takes the stage is the body in which that instrument is housed. He stands just over 4 feet 4 inches tall, on stumpy legs without knee joints or much thigh. His hands (missing two fingers on the left and one on the right) emerge from his shoulders like flippers. He lurches and sways...
  • Drug for Symptoms Turns Out to Be a Surprising Treatment for Blood Disease

    05/15/2005 7:04:53 PM PDT · by Pharmboy · 1 replies · 569+ views
    The Associated Press ^ | May 15, 2005 | Marilynn Marchione
    ORLANDO, Fla. (AP) - Doctors were just hoping to treat symptoms when they gave people with a deadly blood disorder a drug to reduce the need for transfusions. To their astonishment, signs of the disease itself disappeared in nearly half of them. Specialists said the experimental drug, Revlimid, now looks like a breakthrough and the first effective treatment for many people with myelodysplastic syndrome, or MDS, which is even more common than leukemia. "It may be, if not eradicating the disease, putting it into what I would call deep remission," said Dr. David Johnson, a cancer specialist at Vanderbilt-Ingram Cancer...
  • Limbless Woman Says Air France Wouldn't Allow Her On Board

    08/13/2004 9:22:10 PM PDT · by Unknown Freeper · 90 replies · 1,663+ views
    WNBC - News 4 NYC ^ | 08/13/2004 | Associated Press
    NEW YORK -- A limbless woman sued Air France Friday, saying she was prevented from boarding a flight four years ago by an airline employee who insulted her, saying "a head, one bottom and a torso cannot possibly fly on its own." Adele Price, 42, of Mansfield, England, filed the lawsuit in U.S. District Court in Manhattan, seeking unspecified damages and including the quote in her claim. Price said she suffered emotionally, psychologically and endured large expenses as she tried to complete a trip from Manchester, England to New York on Aug. 8, 2000. She said she paid someone else...