For patients with recurrent bleeding due to small-intestinal angiodysplasia (SIA), thalidomide treatment results in a reduction in bleeding, according to a study. Huimin Chen, M.D. and colleagues examined the efficacy and safety of thalidomide for the treatment of recurrent bleeding due to SIA in a randomized, placebo-controlled trial. A total of 150 patients with recurrent bleeding due to SIA were randomly assigned to thalidomide at an oral daily dose of 100 mg (51 patients) or 50 mg (49 patients) or placebo (50 patients) for four months. The researchers found that the percentages of patients with an effective response, defined as...