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Keyword: pharmacology

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  • Gut microbes get first dibs on heart meds

    07/20/2013 4:47:40 PM PDT · by neverdem · 22 replies
    Science News ^ | July 19, 2013 | Jessica Shugart
    Some people harbor a strain of bacteria that chews through cardiac medication The next time you pop a pill, know that the microbes in your gut might get to it before you do. Some people harbor a strain of bacteria that inactivates a common cardiac drug, a finding that could explain why people have different reactions to some medications. “Microbes have long been known to ‘steal’ drugs by converting them into inactive forms,” says Peter Turnbaugh of Harvard University, who led the study. But picking out the specific culprits among the gut’s throngs of bacterial suspects has been a challenge...
  • Beer's taste triggers dopamine release in brain

    04/20/2013 5:34:09 PM PDT · by Jyotishi · 55 replies
    DNA ^ | Tuesday, Apri 16, 2013 | ANI
    The taste of beer, without any effect from alcohol itself, can trigger dopamine release in the brain that is associated with drinking and other drugs of abuse, researchers have claimed. Using positron emission tomography (PET), the researchers at Indiana University School of Medicine tested 49 men with two scans, one in which they tasted beer, and the second in which they tasted Gatorade. The researchers were looking for evidence of increased levels of dopamine, a brain neurotransmitter that has long been associated with alcohol and other drugs of abuse. The scans showed significantly more dopamine activity following the taste of...
  • Magic mushroom drugs could treat severe depression

    04/07/2013 10:47:57 AM PDT · by Jyotishi · 46 replies
    DNA ^ | Sunday, April 7, 2013 | ANI
    Drugs made from magic mushrooms could help treat people with severe depression, a new study suggests. Scientists believe that the chemical psilocybin, the psychedelic ingredient in magic mushrooms, can turn down parts of the brain that are overactive in severely depressive patients, the Guardian reported. The drug appears to stop patients dwelling on themselves and their own perceived inadequacies. However, a bid by British scientists to carry out trials of psilocybin on patients in order to assess its full medical potential has been blocked by red tape relating to Britain’s strict drugs laws. Professor David Nutt, professor of neuropsychopharmacology at...
  • Two ayurvedic drugs hold out hope for Alzheimer’s patients

    04/01/2013 11:21:25 PM PDT · by Jyotishi · 43 replies
    The Indian Express ^ | Tuesday, April 2, 2013 | Pritha Chatterjee
    New Delhi - It's a disease long associated with the elderly but is now diagnosed in younger people as well and with no permanent cure available till date. However, in what could give hope to thousands suffering from Alzheimer's Disease (AD), the pharmacology department in AIIMS has identified Ayurvedic drugs which could have a role in preventing the onset of AD and also restricting its spread in affected patients. AD is a degenerative neurological disorder leading to progressive loss of cognitive abilities, including the patient's memory due to a drop in chemicals — known as neurotransmitters — which transmits messages...
  • Database Finds New Uses for Old Drugs

    08/17/2011 9:31:27 PM PDT · by neverdem · 20 replies
    ScienceNOW ^ | 17 August 2011 | Kai Kupferschmidt
    Enlarge Image Double whammy. Researchers have turned up a pill against heartburn that could be used to treat lung cancer and an antiepileptic pill that might treat Crohn's disease. Credit: Marina Sirota What if a cheap medicine sold over the counter turned out to be a cure against cancer or another deadly disease? Scientists have devised a new way of predicting such unexpected benefits of existing drugs, and they have confirmed two potential new therapies just to prove the point. "This promises new uses for drugs that have already been tested for their safety and offers a faster and...
  • FDA reports 51 deaths of attention drug patients

    02/08/2006 7:38:31 PM PST · by Pharmboy · 57 replies · 2,001+ views
    Reuters ^ | Wed Feb 8, 2006 | Lisa Richwine
    Deaths of 51 U.S. patients who took widely prescribed drugs to treat attention deficit disorder prompted regulators to start watching for heart attacks, high blood pressure and other problems in 2004, a report released on Wednesday said. The U.S. Food and Drug Administration staff did not say the drugs were responsible for the fatalities, but they urged close monitoring for "the rare occurrence of pediatric sudden death during stimulant therapy." "These reports themselves do not establish a causal relationship between these medications and cardiovascular adverse events," wrote Dr. Gerald Dal Pan, director of the FDA's Office of Drug Safety, in...
  • Different Drug Often Works in Depression, Study Finds

    03/23/2006 1:34:20 AM PST · by neverdem · 14 replies · 779+ views
    NY Times ^ | March 23, 2006 | BENEDICT CAREY
    Some people with depression who do not recover with an initial course of antidepressant therapy can increase their chances of finding relief by trying other drug treatments, researchers are reporting today. The study is the most extensive of people undergoing multiple treatments for depression. The findings underscore the benefits of treatment with antidepressants and its limits. Although 20 percent to 30 percent of the patients who used follow-up regimens recovered, the rest did not. The report is the second phase of a government-financed study that has tracked more than 2,800 depressed adults under the care of doctors or psychiatrists. In...
  • Bumper Crop of Scandal Raised in Ill.Cornfields?(Patrick Arnold,Designer-Drugs,Athletes,& the Feds)

    11/28/2005 6:59:08 AM PST · by fight_truth_decay · 9 replies · 1,337+ views
    SignOnSanDiego.com ^ | November 28, 2005 | By Mark Zeigler
    Soon the tentacles of the BALCO doping case had reached into professional baseball and football, into Olympic track and field, into championship boxing, into the very consciousness of the American sports fan. There was grand-jury testimony and U.S. Anti-Doping Agency sanctions and congressional hearings with pumped-up athletes stuffed into designer suits talking about designer steroids. And now the trail has led to a three-story beige building in the cornfields of central Illinois, to a nutritional supplement company called Proviant Technologies and what investigators believe is the true genius behind the whole operation. To a 39-year-old organic chemist who signed off...
  • Seniors and Drugs: Prescribed to death

    04/10/2005 5:47:17 PM PDT · by maine-iac7 · 25 replies · 691+ views
    CBC News ^ | April 10, 2005
    Drugs, not just age and disease, are killing Canadian seniors. As many as 3,300 seniors die every year due to adverse drug reactions, according to a CBC estimate done by analyzing Health Canada's adverse drug reaction database (obtained under Access to Information). It's an estimate that has been judged credible by a number of researchers who study pharmacology and adverse drug reactions. "The 3,300 deaths number and the way it's been calculated by CBC I think is quite cautious and is realistic. It's likely to be higher than that, but nobody at the present time has a way of really...