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  • COVID‐19 vaccination can occasionally trigger autoimmune phenomena, probably via inducing age‐associated B cells

    02/12/2022 7:21:02 AM PST · by Caipirabob · 14 replies
    International Journal of Rheumatic Diseases ^ | November 12th, 2021 | Athanasios Sachinidis and Alexandros Garyfallos
    2. AUTOIMMUNE PHENOMENA FOLLOWING COVID‐19 VACCINATION Autoimmune disease flares and new‐onset disease following coronavirus disease 2019 (COVID‐19) vaccination have recently been reported. 14 , 15 In general, all these cases appeared rare and most of them were moderate in severity and had an excellent resolution of inflammatory features, with the use of corticosteroids alone 14 , 15 (indicating that COVID‐19 vaccines are actually safe). The use of TLR7/8 and TLR9 agonists, as adjuvants of the available mRNA and DNA severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccines, may be the trigger of these post‐vaccination autoimmune/inflammatory phenomena, 14 as it is...