Free Republic

Research in mice shows limited intakes of one particular essential amino acid can slow the impacts of aging and even lengthen their lifespan. Scientists are now wondering if these findings could help people improve their longevity and quality of life. Isoleucine is one of three branched-chain amino acids we use to build proteins in our bodies. It is essential for our survival, but since our cells can't produce it from scratch, we have to get it from sources like eggs, dairy, soy protein and meats. But there can always be too much of a good thing. Earlier research using data...

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging. A research team has now unlocked one responsible mechanism. Professor Dr. David Vilchez used a non-vertebrate model organism, the nematode Caenorhabditis elegans, and cultivated human cells. Both carried the genes for two neurodegenerative diseases that typically occur in old age: amyotrophic lateral sclerosis (ALS) and Huntington's disease. Both diseases are characterized by accumulations of harmful and damaging protein deposits—so-called pathological protein aggregations. In both model organisms, cold actively removed the protein clumps, thus preventing the protein aggregation that is pathological in...

Young blood plasma transfusions for anti-aging are popular with some wealthy elites. There are claims that young blood rejuvenates the body's organs. But turning back the body's clock with transfusions might not need to be done anymore following research from Columbia University in New York that states an anti-inflammatory drug can rejuvenate the body and possibly increase the human lifespan by decades. "An aging blood system, because it's a vector for a lot of proteins, cytokines, and cells, has a lot of bad consequences for the organism," Emmanuelle Passegué, Ph.D., director of the Columbia Stem Cell Initiative, who's been studying...

The portion of the U.S. population fully vaccinated against COVID-19 rose from 0 percent at the outset of 2021 to 63 percent by the end of the year. Yet, the CDC recently estimated that average U.S. life expectancy fell by 0.9 years in 2021. This is in addition to a 1.8 year decline in 2020—and contrary to predictions that COVID vaccines could reverse this carnage. Nevertheless, a New York Times article by Roni Caryn Rabin blames this “historic setback” mainly on a lack of COVID-19 vaccination and not enough “behavioral measures to prevent infections, such as wearing masks,” especially among...

Researchers at the University of Wisconsin have outlined what they call the "longevity diet," based on a century of data, that emphasizes certain foods and periodic fasting, they said, in an article published Thursday. The review of data from hundreds of studies -- involving both people and animals -- showed diets high in legumes, or green vegetables, as well as whole grains, nuts and olive oil can add years to a person's life expectancy, the researchers said in an article published Thursday by the journal Cell. Those who include other vegetables and some fish and dark chocolate, while avoiding red...

Rockfish is on the menu around the Pacific Rim, for the most part with little regard for the fish's origin or which of the 137 species is on the plate—it's typically identified simply as rockfish or, incorrectly, as rock cod or red snapper. But this seemingly anonymous fish—among the longest-lived vertebrates on Earth—holds clues to the genes that determine lifespan and the pluses and minuses of living longer. In a study appearing this week in the journal Science, biologists at the University of California, Berkeley, compare the genomes of nearly two-thirds of the known species of rockfish that inhabit coastal...

The rapid decline in biblical lifespans Mathematics tells us the numbers are not made up by Robert Carter Published: 5 October 2021 (GMT+10) The dramatic decline in human lifespan after the Flood has been studied by many scholars. However, most studies only focus on the chronogenealogies of Genesis 5 and 11, which go from Adam to Terah, the father of Abraham. Yet, it is possible to add multiple additional generations by considering the details given to us in the rest of the Old Testament. The remaining data not only support the Genesis narrative, but they argue strongly that the lifespans...

In this interview, Dr. Vladimir Zelenko discusses an incredibly serious concern, one shared with at least two other highly credible experts — Michael Yeadon, Ph.D., a life science researcher and former VP and chief scientist of allergy and respiratory research at Pfizer, and professor Luc Montagnier, a world-renowned virologist who won the Nobel prize discovery of HIV. Yeadon, Montagnier and Zelenko all believe the COVID-19 shots could reduce life expectancy by several decades, depending on several factors, including whether you’re required to get booster shots. In fact, there may be reason to suspect that many who get the jabs and...

Summary: Scientists have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. The increase in lifespan would be the equivalent of a human living for 400 or 500 years, according to one of the scientists. Share: Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research....

What countries have the longest life expectancies? Author: Marina Pitofsky, USA TODAY Updated: 3:21 PM EDT July 27, 2018 Okinawa, Japan is often known as "the land of immortals," with hundreds of residents over 100 years old. Last year, the number of people 90 years old and above in Japan hit the two million mark. So when Chiyo Miyako died Sunday as the oldest person in the world at 117 years old, she was certainly not alone at her age in Japan. The new oldest person in the world is Kane Tanaka, a 115-year-old woman living in Fukuoka, Japan, according...

The mysterious world of gut bacteria is a hot area of research in science right now. The systemic implications of our gut flora are being found to have vast holistic effects from potentially affecting the symptoms of autism to influencing neurodegeneration in the brain. New research on the turquoise killfish could point to another effect of our gut microbiome – moderating aging. Several studies in recent years have found interesting links between aging and gut microbiota. From mice to men we've seen evidence of age-related differences in the microbiome between the old and young. It seems increasingly clear that as...

Metformin is approved in the US as a treatment for type 2 diabetes. A new study by Cardiff University, UK, involving over 180,000 people, reveals that the drug could also increase the lifespan of those individuals who are non-diabetics. According to the Centers for Disease Control and Prevention (CDC), there are around 29.1 million people in the US with diabetes, equating to 9.3% of the population. Type 2 diabetes accounts for 90-95% of diabetes cases and is usually associated with older age, obesity and physical inactivity, family history of type 2 diabetes or a personal history of gestational diabetes. Senior...

For poor Americans, the place they call home can be a matter of life or death. The poor in some cities — big ones like New York and Los Angeles, and also quite a few smaller ones like Birmingham, Ala. — live nearly as long as their middle-class neighbors or have seen rising life expectancy in the 21st century. But in some other parts of the country, adults with the lowest incomes die on average as young as people in much poorer nations like Rwanda, and their life spans are getting shorter. In those differences, documented in sweeping new research,...

Diet rich in rosemary linked to good health and long life expectancy in Italian village Medical experts will examine pensioners living in Acciaroli near Salerno. They have remarkable record for living for longer but also free of disease. Population of a few thousand has about 300 people who are aged over 100 Mediterranean diet, fresh air and walking thought to influence long lives...

A research team from The Scripps Research Institute (TSRI), Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan. The new research was published March 9 online ahead of print by the journal Aging Cell. The scientists coined the term "senolytics" for the new class of drugs. "We view this study as a big, first step toward developing treatments that can be given safely to patients to extend healthspan or to treat age-related diseases and disorders," said TSRI...

Pensioners will be given estimates of how long they have left to live to help them manage their savings, a minister has disclosed. Steve Webb said that the Government wants to provide pensioners with a rough life expectancy when they reach retirement to allow them to make better financial decisions. Experts will take into account factors including gender, where a pensioner lives or whether they smoke, the pensions minister said. Life expectancy should be part of “guidance” given to help people decide how much to save. In last month’s Budget, George Osborne announced the scrapping of rules that force most...

While most Americans can look forward to living longer than ever, that’s not the case for white women who didn’t graduate from high school. Their life expectancy has actually dropped by five years — from 78 years in 1990 to 73 in 2008. More heartening is the finding that black women without a high school diploma saw their life expectancy increase by a year from 73 to 74. In fact, they can now expect to live a year longer than their white counterparts. The findings are from a study led by S. Jay Olshansky, a longevity researcher at the University...

Here's the link.

Inside a Mouse's Brain Lies a Chemical Key to the Fountain of Youth By Greg Thomas Source image via Wikipedia If a scientist came to you with a plan to tweak a gland in the center of your brain so that you may live to be 140 years old, you'd probably back out of the room slowly and go to file a police report, because that's creepy. But new research shows that it's not altogether impossible. A new report from researchers at the Albert Einstein School of Medicine in the Bronx shows that scientists can tinker with the minds of...

[snip] "In addition, the incidence for schizophrenia is almost doubled for individuals who are born and brought up in cities. "These values are a cause for concern and determining the biology behind this is the first step to remedy the trend." He and colleagues studied a series of brain scans from healthy volunteers from rural and urban areas to reach their conclusion. Dr Pruessner said: "These findings suggest that different brain regions are sensitive to the experience of city living during different times across the lifespan. "Future studies need to clarify the link between psychopathology and these affects in individuals...