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Keyword: insulinresistance

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  • Diabetes may begin more than 20 years before diagnosis

    10/07/2018 6:40:13 PM PDT · by ConservativeMind · 58 replies
    Science Daily/Diabetologia ^ | October 4, 2018 | Dr Hiroyuki Sagesaka and Professor Mitsuhisa Komatsu
    Early signs of type 2 diabetes can be identified more than 20 years before diagnosis, according to new research presented at this year's European Association for the Study of Diabetes (EASD) Annual Meeting in Berlin, Germany (1-5 October). The Japanese study tracked over 27,000 non-diabetic adults (average age 49 years) between 2005 and 2016 and found that increased fasting glucose, higher body mass index (BMI) and impaired insulin sensitivity were detectable up to 10 years before the diagnosis of diabetes as well as prediabetes. [snip] "As the vast majority of people with type 2 diabetes go through the stage of...
  • Gut Bacteria May Spur Obesity, Research Suggests

    03/05/2010 5:07:55 AM PST · by Zakeet · 17 replies · 989+ views
    BusinessWeek ^ | March 4, 2010
    Intestinal bacteria may contribute to obesity and metabolic syndrome, a new study in mice suggests. "It has been assumed that the obesity epidemic in the developed world is driven by an increasingly sedentary lifestyle and the abundance of low-cost, high-calorie foods. However, our results suggest that excess caloric consumption is not only a result of undisciplined eating but that intestinal bacteria contribute to changes in appetite and metabolism," senior study author Andrew Gewirtz, an associate professor of pathology and laboratory medicine at Emory University School of Medicine, said in a university news release. He and his colleagues found that increased...
  • Exercise and Vitamins: Now, Wait A Minute

    05/15/2009 4:45:05 AM PDT · by grey_whiskers · 19 replies · 1,189+ views
    Corante Weblog ^ | 05/13/2009 | Derek Lowe
    ...ROS are also implicated in many theories of aging and cellular damage, which is why cells have several systems to try to soak these things up. That’s exactly why people take antioxidants, vitamin C and vitamin E especially. So. . .what if you take those while you’re exercising? A new paper in PNAS askes that exact question. About forty healthy young male volunteers took part in the study, which involved four weeks of identical exercise programs. Half of the volunteers were already in athletic training, and half weren’t. Both groups were then split again, and half of each cohort took...
  • One protein mediates damage from high-fructose diet

    03/04/2009 1:41:57 AM PST · by neverdem · 15 replies · 756+ views
    Sscience News ^ | March 3rd, 2009 | Laura Sanders
    Sweet reversal: Harmful effects of fructose traced to one protein in a study of mice Knocking out a liver protein in mice can reverse the damaging effects of a super-sweet diet. Diets loaded with high-fructose corn syrup wreak havoc on metabolic processes, but how fructose does its damage has been a mystery. The new study, appearing in the March 4 Cell Metabolism, identifies a possible culprit, a protein in the liver called PGC-1 beta. The new research is “putting together things that we know and making a link,” comments Carlos Hernandez of the University of Michigan in Ann Arbor. The...
  • Type 2 Diabetes: Genes Linked To Insulin Resistance Identified

    10/27/2007 3:53:03 PM PDT · by neverdem · 14 replies · 104+ views
    New research from University of Alabama at Birmingham identifies two genes that may play a role in insulin resistance, opening a new avenue for researchers searching for treatments for type 2 diabetes and metabolic syndrome. The UAB team found that two genes, NR4A3 and NR4A1, seem to boost insulin sensitivity in muscle tissue. Insulin lowers blood glucose, or sugar, by moving it from the bloodstream into skeletal muscle, where it is metabolized for energy or stored for later use. Type 2 diabetes results from either a shortage of insulin or from de-sensitized muscle that does not respond well to insulin,...
  • Middle-aged Adults Melt Away Fat and Metabolic Syndrome (syndrome-x, hyperinsulinism) With Exercise

    01/15/2005 6:13:09 PM PST · by Coleus · 5 replies · 662+ views
    NIH.gov ^ | January, 2005
      Exercising, even moderately, can significantly reduce the risk of metabolic syndrome, a condition that increases heart disease and diabetes risk, among older adults, according to a study.The six-month study involved over 100 people between the ages of 55 and 75. Half were "prescribed" exercises ranging from weightlifting to walking, which were performed for one hour, three times a week. The other participants were given a booklet that encouraged increased activity to promote good health.Some 43 percent of participants had metabolic syndrome when the study began. At the end of six months, the following results were observed among the...