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A new study published in The New England Journal of Medicine has shown that all 18 rectal cancer patients participating in an experimental drug trial went into remission following a six-month treatment. The study, the Journal reported, was spearheaded by doctors at Memorial Sloan Kettering. Drug maker GlaxoSmithKline also backed the research. According to the study, 18 cancer patients who were given the experimental immunotherapy drug dostarlimab every three weeks for six months ended up in remission by the end of the trial. A portion of the study read, “We initiated a prospective phase 2 study in which single-agent dostarlimab,...

A third scientist employed by GlaxoSmithKline pleaded guilty to stealing trade secrets – including the science behind COVID-19 treatments – to boost a competing, state-funded Chinese pharmaceutical company.Lucy Xi, along with three co-defendants, established the Chinese pharmaceutical company Renopharma with funding from the Chinese Communist Party to supposedly research and develop anti-cancer drugs. The team, however, used the company as a vessel to steal information from GlaxoSmithKline (GSK) in the United States.Xi and her colleagues worked at a GSK facility in Upper Merion, Pennsylvania.In January 2015, she sent co-conspirator Yan Mei a GSK document containing “confidential and trade secret data...

TALLAHASSEE (CBSMiami/NSF) — Gov. Ron DeSantis announced Thursday that the state has begun purchasing doses of a monoclonal antibody treatment directly from the pharmaceutical company GlaxoSmithKline, after the federal government last week took control of distribution of the COVID-19 treatments produced by other companies. DeSantis said the first purchase was for 3,000 doses of the drug sotrovimab, which was given emergency-use authorization by the U.S. Food and Drug Administration in May. The governor said last week that he would pursue a direct-purchasing agreement with GlaxoSmithKline, as the state is unable to directly buy doses of Regeneron’s monoclonal antibody treatment. Monoclonal...

Sotrovimab, the newest antibody therapy, was developed by GlaxoSmithKline and Vir Biotechnology after a large collaborative study by scientists from across the nation discovered a natural antibody (in the blood of a SARS survivor, back in 2003) that has remarkable breadth and efficacy. Experiments showed that this antibody, called S309, neutralizes all known SARS-CoV-2 strains – including newly emerged mutants that can now “escape” from previous antibody therapies – as well as the closely related original SARS-CoV virus. Jay Nix, leader of the Molecular Biology Consortium based at Berkeley Lab’s Advanced Light Source (ALS), used beamlines at the ALS and...

Boris Johnson has announced a new partnership with pharmaceutical giant GlaxoSmithKline, to provide 60 million doses of the new Novavax vaccination in the fight against Covid-19. BORIS JOHNSON: And at the same time as we push forward with our program to offer a vaccination to all adults by the end of July, we're building up our own long term UK manufacturing capabilities. I've already told you that Novavax, a potentially significant new weapon in our armory against COVID, is going to be made at Fujifilm in the northeast. And I can today announce that the vaccine taskforce has reached an...

GlaxoSmithKline fired Moncef Slaoui — the feds’ former coronavirus vaccine czar — from one of its subsidiaries after an internal probe found he had sexually harassed one of the British drugmaker’s employees.GSK said Wednesday it booted Slaoui from his post as chairman of the board of Galvani Bioelectronics, a medical research firm that’s majority-owned by the pharma giant.

July 11, 2017 CoG for Life http://www.fiercepharma.com/vaccines/eager-for-marketing-approval-gsk-s-shingrix-passes-revaccination-test With GlaxoSmithKline eager for marketing approval, Shingrix passes revaccination test Awaiting a potential FDA approval, GlaxoSmithKline’s much-anticipated shingles vaccine Shingrix met its goal in a phase 3 study examining whether it can protect older adults who have previously received Merck’s Zostavax. If approved, CDC officials said they’re likely to recommend the GSK vaccine over Merck’s shot. In the revaccination study, investigators found that Glaxo’s shot induces a strong immune response in people 50 and older who received Zostavax a minimum of 5 years before their Shingrix vaccination. Since previous studies have shown Zostavax’s...

Gripe as we might, consumers understand that price increases do happen. What’s not as easily understood is how the price for something can go from $13.50 one day to $750 the next — especially when it’s a generic drug used to save lives. For decades, Daraprim (pyrimethamine), an anti-parasitic used to treat malaria and toxoplasmosis, had been made by GlaxoSmithKline and sold for as little as $1/tablet until not that long ago. Then in 2010 GSK sold the drug to CorePharma, which began to raise the price. Within a year, revenue from Daraprim jumped nearly ten times even though the...

China Fines GlaxoSmithKline Nearly $500 Million in Bribery Case By KEITH BRADSHER and CHRIS BUCKLEY SEPT. 19, 2014 HONG KONG — Global multinationals have invested billions of dollars in China over the last decade, with the prospect of selling to 1.4 billion people. But the promise of China’s growth is increasingly offset by the dangers of being caught up in the country’s anticorruption campaigns and rising economic nationalism. In the strongest signal yet, a Chinese court on Friday imposed a fine of nearly $500 million on the British pharmaceutical giant GlaxoSmithKline for bribery, dwarfing the penalties in earlier criminal cases

Part 1: “IT’S A NIGHTMARE” After the Avandia debacle, is history about to repeat itself? Amy Lynn Evans remembers the onset of the illness that left her with seven hundred thousand dollars in medical bills. The morning began like any other. “My son was getting ready for work, and he said to me ‘Mom, you don’t look too well.’ When I went to the emergency room, they found a blood clot on my lung.

A GlaxoSmithKline executive and a British private detective and his wife, who were initially hired by GSK to investigate smears, face prison in a tale akin to a spy mystery The story has all the makings of a sensational spy thriller, from allegations of corruption by one of the world’s biggest pharmaceutical firms and the appearance of a sex tape involving a senior executive, to the arrest of British citizens by a foreign power. It certainly cannot have been what Mark Reilly expected when he was promoted to head-up GlaxoSmithKline (GSK) pharmaceuticals division in China, in 2009. A 25-year veteran...

Shanghai police formally arrested Peter Humphrey on Monday, in a sign that authorities believe they have enough evidence for a case to be brought to trial. He and his wife, Yu Yingzeng, were detained in Shanghai on July 10, along with around eight other individuals, as police probed bribery allegations against British drug giant GlaxoSmithKline. Mr Humphrey and Ms Yu, both well-known corporate investigators in China, run Hong Kong-based ChinaWhys, a risk consultancy that focuses on fraud and accounting for multinational businesses operating in the country. Chinese authorities have not given the specific reason behind the pair’s detention, but a...

LOS ANGELES (KTLA) -- Celebrity addiction specialist Dr. Drew Pinsky is under fire for helping market an antidepressant for uses not approved by the Food and Drug Administration. GlaxoSmithKline, which makes the drug Wellbutrin, agreed to pay a $3 million fine on Friday in a Boston courthouse. The British drugmaker reportedly paid "Lifechangers" host Dr. Drew $275,000 to promote the antidepressant for non-approved uses such as obesity, addictions and sexual dysfunction.

WASHINGTON -- GlaxoSmithKline LLC will pay $3 billion and plead guilty to promoting two popular drugs for unapproved uses and to failing to disclose important safety information on a third in the largest health care fraud settlement in U.S. history, the Justice Department said Monday. Accompanying the criminal case was a civil settlement in which the government said the company's improper marketing included providing doctors with expensive resort vacations, European hunting trips, high-paid speaking tours and even tickets to a Madonna concert. The $3 billion combined criminal-civil fine will be the largest penalty ever paid by a drug company, Deputy...

It's one thing to have a philosophical disagreement with the Texas governor on whether he should have mandated a vaccine for girls against a sexually transmitted virus. But it's an entirely different matter to spread false rumors about the vaccine, hoping to leverage parental fears for political gain. That's the depths to which Minnesota's Michele Bachmann has sunk in her bid to counter Rick Perry's surge in polls. It's conduct unbecoming a member of Congress, much less a candidate for the Republican presidential nomination. Bachmann used the issue last week at the CNN/Tea Party Express debate in Tampa to land...

Reporting from Costa Mesa— Michele Bachmann, struggling to regain her footing in the GOP presidential contest, Friday assailed rival Rick Perry, saying he abused his power as governor of Texas and rewarded political donors in a manner similar to President Obama. (snip) She compared it to the federal controversy unfolding around Solyndra, a solar equipment maker that received a $535-million federal loan guarantee and which went bankrupt last month. Republicans have suggested that the guarantee was pushed by the White House to reward a major campaign donor with ties to Solyndra's biggest shareholder, a charge the Obama administration denies. Bachmann...

good times good times. Meanwhile, Bachman has taken somewhere north of $140,000 from pharmaceutical companies. Those donors include Abbott Labs, Pfizer, GlaxoSmithKline, AstraZeneca, Novartis, Eli Lilly and Bayer. Yet, not a dollar of all that pharma money, from such a wide range of the world’s largest drugmakers, came from Merck. Might Bachmann be going after Merck on behalf of that company’s competitors who also happen to be Bachmann donors? She’s claiming a vaccine manufactured by Merck (Gardisil) causes mental retardation. Meanwhile, she’s taking campaign donations from Merck’s top HPV vaccine (Cervarix) competitor, GlaxoSmithKline.Hey, that’s not at all suspicious.Weren’t we...

LONDON — Canadian doctors have been advised not to use a batch of 170,000 swine flu vaccines after six reports of serious allergic reactions among recipients, but there are no similar reports from other countries, pharmaceuticals company GlaxoSmithKline PLC said Tuesday. Authorities routinely monitor vaccines for any signals of problems, such as the allergic reactions that do occur, rarely, every year. Company spokeswoman Gwenan White said that GlaxoSmithKline advised medical staff in Canada ast week to refrain from using one batch of the vaccine while they look into reports that that it might have caused more allergic reactions than normal....

An influential psychiatrist who was the host of the popular public radio program “The Infinite Mind” earned at least $1.3 million from 2000 to 2007 giving marketing lectures for drugmakers, income not mentioned on the program. The psychiatrist and radio host, Dr. Frederick K. Goodwin, is the latest in a series of doctors and researchers whose ties to drugmakers have been uncovered by Senator Charles E. Grassley, Republican of Iowa. Dr. Goodwin, a former director of the National Institute of Mental Health, is the first news media figure to be investigated. Dr. Goodwin’s weekly radio programs have often touched on...

A third pharmaceutical giant said Sunday it is being investigated by Britain's Serious Fraud Office (SFO) over alleged breaches of the United Nations oil-for-food programme in Saddam Hussein's Iraq. Eli Lilly and Company Limited said it had been asked to hand over documents to the SFO, a day after British peer GlaxoSmithKline (GSK) and Anglo-Swedish firm AstraZeneca announced they had received similar requests.