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Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug, a multi-institution, Phase 3 clinical trial led by researchers has found. The approach can extend the time between debilitating drug treatments without prolonging the time it takes to recover from each treatment. Prostate cancer is usually treated with one of several testosterone-lowering drugs for a set period of time. "This adds to a growing body of evidence in favor of more intensive testosterone-blocking therapy in patients with higher-risk prostate cancer," said Rahul Aggarwal, MD. The new study focused on...

Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells' resistance to docetaxel, a commonly-used chemotherapy drug to treat advanced cancer that has spread beyond the prostate. The discovery opens the door to new treatment strategies that could overcome this resistance. The study showed that blocking CHRM1 in resistant prostate cancer cell lines and an animal model based on patient-derived resistant tissue restored docetaxel's ability to kill cells and stop tumor growth. The researchers did this by using dicyclomine, a drug that selectively inhibits CHRM1 activity. Dicyclomine is already on the market as...

Researchers have discovered that a certain type of chemotherapy improves the immune system's ability to fight off bladder cancer, particularly when combined with immunotherapy. These findings may explain why the approach, cisplatin chemotherapy, can lead to a cure in a small subset of patients with metastatic, or advanced, bladder cancer. Researchers also believe that their findings could explain why clinical trials combining another type of chemotherapy, carboplatin-based chemo, with immunotherapy have not been successful but others that use cisplatin with immunotherapy are successful. "We have known for decades that cisplatin works better than carboplatin in bladder cancer, however, the mechanisms...

Sen. John Barrasso’s (R-WY) wife has passed away following a two-year battle with brain cancer. Barrasso, who is the chairman of the Senate Republican Conference, announced Thursday that his wife, Bobbi, died after fighting glioblastoma, a type of cancer that causes brain tumors. “After a courageous battle with cancer, Bobbi is now at peace and at home with the Lord,” the senator said in a statement obtained by Fox News: In addition to being a devoted wife and mother, Bobbi was a leader, fierce advocate for Wyoming, and friend to everyone she met. We miss her dearly. On behalf of...

A few years ago, a patient was cured of multiple myeloma after being treated for hepatitis C. Multiple myeloma is one of the most common cancers of the blood. The desire to understand how this patient was cured has led to the discovery that hepatitis B and C viruses are one of the causes of multiple myeloma, and eliminating infection with antivirals is often the way to fight this type of cancer. Multiple myeloma (MM) is an excessive proliferation of blood cells that make antibodies (also called immunoglobulins), the proteins that defend the body from infections. In myeloma, a certain...

FIRST ON THE DAILY SIGNAL—A veteran social worker who says she was fired for expressing concern over racial harassment against her as a Jewish woman and political harassment over her ties to the Trump administration is suing for wrongful termination. Tammy Weitzman last week sued her former employer, the Seattle Cancer Care Alliance, now known as the Fred Hutchinson Cancer Center, for racial and political discrimination and for retaliating against her when she spoke up about it. “I was called a white k–e, and I was harassed over knowing a high-ranking Cabinet member in the Trump administration,” Weitzman told The...

A Harvard University-affiliated teaching hospital is seeking to retract or correct dozens of papers authored by four of its top researchers — including the hospital’s CEO — following a probe into allegations of data falsification. The Dana-Farber Cancer Institute in Boston has already initiated six retractions to papers and 31 others are in the process of being corrected, the hospital’s research integrity officer, Dr. Barrett Rollins, confirmed to the Harvard Crimson. The corrections follow claims of data falsification leveled against the cancer institute’s CEO, Dr. Laurie Glimcher, chief operating officer Dr. William Hahn, director of the Clinical Investigator Research Program...

A recent report published by the American Cancer Society predicted that new cancer cases are expected to reach a new high in 2024. Over 2 million new cases of cancer are expected. Cancer incidence has been rising for six of the most common cancers: breast, prostate, endometrial, pancreatic, kidney, and melanoma. As Leo Hohmann reported earlier. The Wall Street Journal reports that doctors are baffled by the sudden rise in cancer among young people. As Americans Scramble to Protect Retirement Accounts With Physical Gold and Silver, A Faith-Based Company Shows Them How The Journal writes: “Cancer is hitting more young...

Scientists believe that aging can increase the spread of ovarian and other cancers. Now, researchers have found that ovarian cancer cells can spread more easily in tissues that are senescent or aged because these tissues secrete a unique extracellular matrix that attracts the spreading cancer. What they found was that the cancer cells chose to settle down more on the aged tissues; moreover, they settled closer to the aged normal cells in the cell sheets. To figure out what was drawing the cancer cells to the aged cells, the team first wondered if they were being attracted to signaling molecules...

Extracts of a plant used in traditional medicine for centuries have shown anti-proliferative effects against breast cancer in a small early-stage clinical trial. Researchers provided breast cancer patients with an extract of the Boswellia tree—probably best known as the source of frankincense—and instructed them to take it each day until surgery. The researchers then compared the activity of cancer cells in each woman's tumor removed during surgery with the activity in the piece of her tumor that was removed during the biopsy. "We looked at differences in the growth rate of the tumors before and after treatment, and we found...

Data from the St. Jude lifetime cohort study (St. Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors. Early detection through screening using these two biomarkers may lead to earlier treatment to prevent and protect against further heart damage. Cardiomyopathy is often asymptomatic at onset and thus "invisible" to routine clinical evaluations. Scientists found that two common biomarkers, global longitudinal strain (GLS) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP), could identify survivors with otherwise normal-appearing heart function who are at elevated...

Yesterday the Expose published an article which highlighted just a few of the various diseases that were found to be potentially caused by parasites, including cancers. A recent review of nine published research papers by Doctor William Makis further supports the views in the article, but Dr Makis is more qualified to say “it is a reasonable hypothesis that COVID-19 mRNA Vaccine Turbo Cancer patients could benefit significantly from anti-parasitic drugs.” One anti parasitic drug in particular, Fenbendazole, however, has not been sanctioned for human use by the FDA, but despite lacking “official” approval, it is cheap, safe and more...

Researchers at The University of Texas at El Paso have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of therapy. Renato Aguilera, Ph.D., a professor in the Department of Biological Sciences, is the principal investigator on the project that identified the promising compound, called thiophene F-8. His team's findings were published in the journal PLOS One. "The main goal of my research is to discover new anticancer drugs that can eventually treat distinct cancer types," Aguilera explained. "This research not only had amazing results, it also led to...

Of 85 products tested, a popular organic pasta product had the highest levels These chemicals have been linked to cancer and other serious health conditions READ MORE: Average water bottle contains 240k pieces of nanoplastics 'Forever chemicals' linked to cancer are found in virtually every food product sold in American stores, a shocking report suggests. The watchdog Consumer Reports tested 85 everyday items for the presence of phthalates and bisphenols, two types of PFAS chemicals used to make plastics. The researchers tried to make their sample size as broad as possible - testing water, soda, cereal, bread, meat, fish, condiments,...

U.S. Defense Secretary Lloyd Austin was recently diagnosed and is being treated for prostate cancer. He is one of the nearly 290,000 American men who will be diagnosed with the condition this year. Nearly all types of cancer have become less deadly over the last 30 years, with one notable exception: advanced-stage prostate cancer, according to a recent report from the American Cancer Society (ACS). “We have had more men diagnosed with more advanced prostate cancer over the last decade,” Dr. Sam S. Chang, the Chief Surgical Officer at the Vanderbilt Ingram Cancer Center, told The Epoch Times in an...

Meilin Keen was studying for the bar exam and preparing to move to New York City last June when she started throwing up blood. Keen, 27 years old, learned days later that she has gastric cancer. She postponed the bar exam. Brain fog from chemotherapy made it hard to do her legal work. Surgeons removed her stomach in December. Keen is coming to terms with all that means for her diet, her health, even her dating life. “That’s a fun icebreaker: I don’t have a stomach anymore,” she said. Cancer is hitting more young people in the U.S. and around...

Defense Secretary Lloyd Austin was diagnosed with prostate cancer in December and underwent a minimally invasive procedure to treat and cure it, according to a statement from Walter Reed National Military Center officials on Tuesday. "Secretary Austin recovered uneventfully from his surgery and returned home the next morning. [snipped out section quoting officials saying his prognosis is excellent] Austin was then admitted to Walter Reed on Jan. 1 "with complications from the December 22 procedure, including nausea with severe abdominal, hip, and leg pain," the officials said.

ULSAN, South Korea — South Korean researchers from the Ulsan Institute of Science and Technology (UNIST) have developed a cutting-edge method to treat cancer using tiny, specialized devices called “nanodrones.” These revolutionary nanodrones are engineered to specifically target and destroy cancer cells. To understand this, we first need to know about Natural Killer (NK) cells. NK cells are a type of white blood cell that play a vital role in defending our body against cancer. Scientists have long aimed to use these cells in cancer treatment. The UNIST team’s breakthrough, named NKeNDs (NK cell-engaging nanodrones), utilizes a kind of nanoparticle...

Harvard University’s Provost and Interim President Dr. Alan Garber has made millions from sitting on pharmaceutical company boards during his time with the school. Garber made more than $2.7 million from board seats with pharmaceutical firms Exelixis, Inc. and Vertex Pharmaceuticals since becoming Harvard provost in 2011, the Harvard Crimson reported in 2019, citing company filings with the Securities and Exchange Commission (SEC). Both firms confirmed to the outlet Garber received compensation without performing any additional duties beyond his board memberships. ... He joined Exelixis’ board in 2005 and received $2.3 million from the company, $1.6 of which came after...

Pfizer has stunned the medical world, completing the $43 billion acquisition of Seagen, a small drug company that treats turbo cancers and barely makes $2 billion per year. The acquisition means Pfizer becomes the largest oncology company in the world, capable of treating most turbo cancers caused by mRNA vaccines. However, the nature of the acquisition has left many people scratching their heads. Why would Pfizer, flush with the enormous profits it has reaped through its mRNA vaccine, overpay $43 billion for a small cancer drug company? Pfizer does not need the cash. It will also issue $31 billion in...