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Rapid mental rejuvenation in old mice suggests age-related losses may be broadly reversible. Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals. In the new study, published on December 1, 2020, in the open-access journal eLife,...

FULL TITLE: U of Michigan “just killed my son,” mother says. Hospital yanks life support hours after judge dismisses case ANN ARBOR, Michigan, October 16, 2019 – Bobby Reyes, a 14-year-old boy from Michigan who doctors declared “brain dead,” died yesterday after a judge dismissed his family’s court case asking he be given more time. The University of Michigan C.S. Mott Children’s Hospital removed his ventilator just hours later. The case was heard at 10:00 a.m. and by 3:00 p.m. the hospital had released a statement declaring Bobby to be dead. Bobby suffered a cardiac arrest on September 21 after...

Hillary Health Horrors Medical experts raise red flags, question her claimed recovery from brain trauma. January 8, 2016 Matthew Vadum A traumatic brain injury Hillary Clinton suffered that she apparently never recovered from could render her unfit for the intense daily rigors of the presidency, a new report suggests. After the former secretary of state returned late to the stage following a commercial break in a Democratic presidential candidates' debate in New Hampshire last month, many observers picked up on an excuse that there was a long lineup for the bathroom that forced Clinton to return to the stage...

Karl Rove created a stir with his recent suggestion that former Secretary of State Hillary Rodham Clinton may have suffered traumatic brain injury in December 2012. Speaking at a conference in California, he noted, “Thirty days in the hospital? And when she reappears, she’s wearing glasses that are only for people who have traumatic brain injury? We need to know what’s up with that.” Let’s ignore the media hyperventilating and look at what Rove actually suggested. Secretary Clinton reportedly “fainted, fell and banged her head,” as The Daily Beast put it, suffering a subdural hematoma, or a hemorrhage between her...

Reviewed by F. Perry Wilson, MD, MSCE; Instructor of Medicine, Perelman School of Medicine at the University of Pennsylvania Action Points Note that this case-control study of concussed football players with mood and cognitive symptomatology showed higher uptake of a tau-specific tracer in MRI scans compared with healthy controls.Be aware that, as the burden of depression was lower in the control group, the findings of increased tau-protein among cases may be due to depression or cognitive impairment and independent of head injury history. A new imaging technique has allowed detection of tau protein abnormalities in the concussed brains of living...

With each bone-breaking, head-injuring hit, NFL players are killing themselves slowly. It’s not a possibility. It’s a fact, no less certain than the league’s immense profitability. Football injuries can kill in a variety of ways. One particularly tragic way might be by making life unbearable for the afflicted. And autopsies have revealed that several former players who committed suicide suffered from brain trauma caused by repeated blows to the head.

A Texas children's hospital is working with the University of Texas' Medical School in a unique clinical trial using bone marrow stem cells to treat children's brain trauma. This trial, which does not involve ethically problematic and controversial embryonic stem cells, is the first to use stem cells in the treatment of traumatic brain injury, for which there is currently no reparative therapy. Dr. James Baumgartner, M.D., is an associate professor of pediatric neurosurgery and one of the principal investigators on the project. He says this procedure will be "an absolutely novel treatment, the first ever with potential to repair...