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Keyword: antibodies

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  • Meet the Tiny Company Behind the Experimental Antibodies for Ebola

    08/05/2014 8:24:52 AM PDT · by SeekAndFind · 12 replies
    WPRO 630 ^ | 08/05/2014
    (SAN DIEGO) -- The companies manufacturing an experimental drug treating two American Ebola patients aren't among the largest multinational pharmaceuticals in the world. In fact, leading the effort is a small nine-employee firm in San Diego. Mapp Biopharmaceutical Inc., founded in 2003, says on its website that it develops, "novel pharmaceuticals for the prevention and treatment of infectious diseases, focusing on unmet needs in global health and biodefense." Mapp's commercialization arm is LeafBio Inc., which has no employees and just two owners, Mapp President Larry Zeitlin tells ABC News. Mapp, along with LeafBio and Defyrus Inc. in Toronto, Canada, collaborated...
  • Researchers Identify New Source of Powerful Immunity Protein

    08/05/2013 6:11:33 PM PDT · by neverdem · 10 replies
    ScienceDaily ^ | July 10, 2013 | NA
    Researchers at UT Southwestern Medical Center report the identification of a new cellular source for an important disease-fighting protein used in the body's earliest response to infection. The protein interferon-gamma (IFN-γ) keeps viruses from replicating and stimulates the immune system to produce other disease-fighting agents. Neutrophils, the newly identified cellular source of the protein, are the major component of the pus that forms around injured tissue. The researchers also report that the neutrophils appear to produce IFN-γ through a new cellular pathway independent of Toll-like receptors (TLRs): the body's early warning system for invasion by pathogens. This finding indicates that...
  • Immune system molecule with hidden talents

    01/24/2013 2:41:11 PM PST · by neverdem · 3 replies
    Biology News Net ^ | January 22, 2013 | NA
    Dendritic cells, shown here in an electron microscopic picture, need antibodies produced by B cells for their maturation. Dendritic cells, or DCs for short, perform a vital role for the immune system: They engulf pathogens, break them down into their component parts, and then display the pieces on their surface. This in turn signals other immune cells capable of recognizing these pieces to help kick-start their own default program for fighting off the invaders. In order to do their job, the DCs are dependent upon the support from a class of immune system molecules, which have never before been associated...
  • Panda Blood Compound 6x More Powerful Than Current Antibiotics

    01/01/2013 1:54:41 PM PST · by DogByte6RER · 31 replies
    DVICE ^ | Jan 1, 2013 | Evan Ackerman
    Panda blood compound 6x more powerful than current antibiotics In what could be either very good news or very bad news for our fluffy black and white friends, it's been discovered that panda blood contains an antibiotic compound that's vastly more powerful than anything we've got right now. Researchers at the Life Sciences College of Nanjing Agricultural University in China have extracted a compound called cathelicidin-AM from the blood of giant pandas. Cathelicidin-AM is what's called a gene-encoded antimicrobial peptide, a natural antibiotic that's produced by a panda's immune cells. Testing has shown that cathelicidin-AM can kill even drug resistant...
  • Anti-terror antibodies

    08/29/2009 12:49:30 PM PDT · by neverdem · 1 replies · 286+ views
    Chemical Biology ^ | 26 August 2009 | Victoria Steven
    European scientists have developed a method to detect potential biological warfare agents in food. "A possible scenario for a bioterrorism attack could involve food contamination with protein toxins"A possible scenario for a bioterrorism attack could involve food contamination with protein toxins, such as ricin and botulinum neurotoxins, says Brigitte Dorner, researcher into microbial toxins, of the Robert Koch Institute in Berlin. However, until now detecting toxins in such complex samples has been difficult.Dorner and colleagues in Germany and Switzerland have devised a highly sensitive system that can detect trace amounts of the toxins in foods such as milk, baby food...
  • Old seasonal flu antibodies target swine flu virus

    05/23/2009 1:26:09 AM PDT · by neverdem · 8 replies · 816+ views
    Nature News ^ | 21 May 2009 | Heidi Ledford
    Lab results could explain why young patients are hardest hit by current H1N1 strain. Antibodies against some seasonal flu strains from prior years may be active against the new H1N1 swine flu currently circulating the globe, a recent study reports. The findings suggest an explanation for why swine flu appears to infect the young more often than the elderly, who are normally more susceptible to seasonal flu viruses.Only 1% of swine flu cases in the United States are in people over the age of 65.CDC The study, published today in the Morbidity and Mortality Weekly Report, analyzed blood samples taken...
  • A Blight to Remember (1918 flu antibodies still work!)

    08/21/2008 11:52:47 PM PDT · by neverdem · 16 replies · 251+ views
    ScienceNOW Daily News ^ | 18 August 2008 | Jennifer Couzin
    Ninety years later, survivors of the worst epidemic in history still retain knowledge of the event--on a cellular level. Scientists have found that the immune systems of a group of 90- and 100-year-olds continue to produce antibodies to the virus responsible for the 1918 flu pandemic, which killed as many as 40 million people. What's more, the antibodies still work: When transferred to mice, the rodents became resistant to deadly flu infections. It doesn't take a global pandemic to rile up the immune system. Even the seasonal flu prompts immune cells called B cells to generate antibodies specific to the...
  • Idaho lab develops a quicker way to catch a thief

    04/28/2008 11:47:55 AM PDT · by jazusamo · 13 replies · 165+ views
    The Columbian ^ | April 28, 2008 | Todd Dvorak AP
    IDAHO FALLS, Idaho (AP) -- Federal researchers say they've developed a human identification test that's faster and possibly cheaper than DNA testing. It would be a handy new weapon in the arsenal for detectives, forensic experts and the military, though no one expects it to replace DNA analysis - and its promoters say it is not intended to. The new method analyzes antibodies. Each person has a unique antibody bar code that can be gleaned from blood, saliva or other bodily fluids. Antibodies are proteins used by the body to fend off viruses or perform routine physiological housekeeping. "DNA is...
  • Portable Dipstick to Measure Caffeine

    05/11/2006 11:25:54 PM PDT · by anymouse · 17 replies · 731+ views
    LiveScience ^ | 5/12/06
    While it might seem strange scientists would think to develop dipsticks to measure caffeine, how they're making them is even weirder. How about three llamas and two camels. The animals, both called camelids by scientists, are among the few whose immune systems produce antibodies that are not destroyed by hot coffee. We did not look into who figured that out or why. Anyway, the researchers injected proteins linked to caffeine into the five beasts to elicit an immune response. The animals produced antibodies in their blood that were reactive to caffeine. Then in the lab, these antibodies were found to...
  • Horse Antibodies Could Combat A Bird Flu Outbreak

    03/28/2006 11:25:50 AM PST · by blam · 13 replies · 417+ views
    New Scientist ^ | 3-28-2006 | Debora MacKenzie
    Horse antibodies could combat a bird flu outbreak 12:16 28 March 2006 NewScientist.com news service Debora MacKenzie An old-fashioned method may offer a cheap and quick way to protect against the H5N1 bird flu virus. Chinese scientists have produced antibodies in horses that are an effective treatment for bird flu at least in mice. Jiahai Lu at Sun Yat-sen University in Guangzhou and colleagues repeatedly inoculated horses with a chicken vaccine against H5N1 bird flu to make them produce antibodies. They then collected the horses blood, separated out the antibodies and split them to make them less likely to...
  • New Method Enables Researchers To Make Human SARS Antibodies Quickly

    07/12/2004 12:17:09 PM PDT · by LibWhacker · 163+ views
    Bio.com ^ | 7/12/04
    07/12/04 -- Human antibodies that thwart the SARS virus in mice can be mass-produced quickly using a new laboratory technique developed by an international research team collaborating with the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health. The new technique could become an important tool for developing a cocktail of SARS-specific antibodies that might help protect people recently exposed to the SARS virus or at high risk of exposure. The technique could also make possible the development of a similar approach to prevent or treat other illnesses, such as HIV/AIDS and hepatitis C....
  • China Makes Breakthrough in SARS Vaccine, Drug

    06/25/2003 8:50:11 PM PDT · by Enemy Of The State · 20 replies · 190+ views
    Major Achievements in SARS Vaccines, Drugs Chinese scientists have made another breakthrough in the creation of a SARS vaccine, as antibodies against the virus have been discovered in monkeys after they had been injected with inactive versions of the vaccine China's Vice-Minister of Science and Technology Li Xueyong said Wednesday that the country has made key progress in vaccines, drugs and diagnostic kits for severe acute respiratory syndrome (SARS). The science sector had achieved significant progress, including the development of a primate infection model, said Li, who is also the deputy team leader of the science and technology group...
  • Experts Claim to Have Discovered SARS Antibodies

    05/17/2003 7:43:21 AM PDT · by riri · 15 replies · 361+ views
    China Daily ^ | 5.16.03
    A Chinese newspaper reports that Chinese experts claim discovery of SARS antibodies that may one day help protect people against the disease. The China Daily quotes Li Gang, a medical researcher specializing infectious disease as saying that after three months of research his team has detected two kinds of antibodies - IgG and IgM - in SARS patients. Mr. Li says IgG, or Immunoglobulin G, is what all SARS patients have during recuperation and on recovery. Mr. Li says people who have recovered from the disease should be traced to see they still have the antibody. He predicted that vaccines...
  • Doctors use antibodies to treat SARS victims

    03/31/2003 8:57:58 AM PST · by BallandPowder · 6 replies · 190+ views
    http://www.reutershealth.com/ ^ | 03/31/2003 | Tan Ee Lyn
    HONG KONG (Reuters) - Doctors in Hong Kong have successfully treated some patients with the killer respiratory disease using serum from recovered patients, a top doctor and public health expert said on Monday. This leads doctors to believe that some people with the respiratory disease have been able to produce antibodies, which are found in serum, to fight the illness. Some experts had earlier assumed and feared that this would not happen as the body might not easily develop antibodies. The disease, known as severe acute respiratory syndrome (SARS), began in southern China in November and later spread to Hong...
  • HIV/Aids Debate Continues

    06/10/2002 3:25:04 PM PDT · by JameRetief · 22 replies · 640+ views
    AllAfrica.com ^ | June 6, 2002 | Dr. David Rasnick
    HIV/Aids Debate ContinuesBusiness Day (Johannesburg) OPINION June 6, 2002 Posted to the web June 6, 2002 David Rasnick Johannesburg ON APRIL 23 1984, Margaret Heckler, then US health secretary, promised an AIDS vaccine by 1986. Now, June 3 2002, Medical Research Council president Malegapuru Makgoba says that expectations of a vaccine within seven to 10 years are realistic. It seems that the older the AIDS epidemic gets, the longer we have to wait for an AIDS vaccine.The uncertainty on efficacy is just the tip of the iceberg of the problems facing an AIDS vaccine. For example, Makgoba fails to say...