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Parkinson's dyskinesia mechanism explained
Science Daily ^ | 01 May 2020

Posted on 05/04/2020 5:45:36 AM PDT by zeestephen

Many people with Parkinson's disease eventually develop debilitating movements called dyskinesia, a side effect of their much-needed dopamine replacement medication. The mechanism underlying this unwanted side effect has been unknown, until now. An international collaboration led by Scripps Research, Florida has found a key cause, and with it, potentially, a new route to providing relief.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: News/Current Events
KEYWORDS: dopamine; parkinsons

1 posted on 05/04/2020 5:45:37 AM PDT by zeestephen
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To: zeestephen

Since I am a Parkinson’s sufferer, this is good to know.


2 posted on 05/04/2020 6:19:40 AM PDT by Blood of Tyrants (Tyrants don't just give you your freedoms back. You have to take them.)
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To: zeestephen

This is wonderful news. I will pray that it is successful and that it can be implemented swiftly.


3 posted on 05/04/2020 6:22:27 AM PDT by Tomato lover (Faith can survive without freedom. But, freedom cannot survive without faith. Come quickly, Jesus)
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To: zeestephen

So the medication that treats the jerky motions of Parkinson’s cause its own jerky motions? Is that correct?


4 posted on 05/04/2020 6:59:48 AM PDT by Sans-Culotte (With every passing day, I am a little bit gladder that Romney lost in 2012.)
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To: Blood of Tyrants

Ping for a later private message


5 posted on 05/04/2020 7:10:41 AM PDT by babygene (hMake America Great Again)
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To: Sans-Culotte

Yes.


6 posted on 05/04/2020 7:14:04 AM PDT by JusPasenThru (American gerbilism is dead. The MSM killed it.)
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To: Sans-Culotte
Not really.

The loss of dopamine impacts a whole range of issues like memory, stiffness, balance.

Dopamine is also involved in starting physical movements, which is why many Parkies seem to get “stuck” when they try to walk or begin other activities.

Most of the jerky or repetitive motions are caused by their Parkinson's medication.

7 posted on 05/04/2020 7:36:26 AM PDT by zeestephen
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To: Sans-Culotte

Parkinson’s causes rythmic tremors that are about 2 tremors per second mostly at rest. The dyskinesia is another problem of slower, jerkier movements. I can do most anything anyone else can do except hold my left hand still. When I move, it’s as smooth as before. The meds pretty much eliminate the stiffness but I can’t tolerate the dosage required to end the tremors without the dyskinesia, which is worse than the tremors.


8 posted on 05/04/2020 12:03:07 PM PDT by Blood of Tyrants (Tyrants don't just give you your freedoms back. You have to take them.)
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