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A "huge milestone": approval of cancer-hunting virus signals new treatment era
The Guardian ^ | 11-2-2015 | Nicky Woolf

Posted on 11/03/2015 7:50:47 AM PST by Ellendra

A new cancer treatment strategy is on the horizon that experts say could be a game-changer and spare patients the extreme side effects of existing options such as chemotherapy.

Chemotherapy and other current cancer treatments are brutal, scorched-earth affairs that work because cancer cells are slightly - but not much - more susceptible to the havoc they wreak than the rest of the body. Their side effects are legion, and in many cases horrifying – from hair loss and internal bleeding to chronic nausea and even death.

But last week the Food and Drug Administration (FDA) for the first time approved a single treatment that can intelligently target cancer cells while leaving healthy ones alone, and simultaneously stimulate the immune system to fight the cancer itself.

(Excerpt) Read more at theguardian.com ...


TOPICS: Culture/Society; Government; Miscellaneous
KEYWORDS: cancer; cancercure; cure; fda; virus
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I did a quick search and didn't find this posted yet. I know there are FReepers right now struggling with cancer, I hope they find this useful.
1 posted on 11/03/2015 7:50:47 AM PST by Ellendra
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To: Ellendra

These cancer “game-changer” therapy stories come up once or twice a year. Usually, they’re not heard from again.

That said, some of them do pan out. Cancer is far more survivable today than it was thirty years ago.


2 posted on 11/03/2015 7:52:50 AM PST by Steely Tom (Vote GOP: A Slower Handbasket)
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To: JRandomFreeper

I don’t know if there’s a cancer ping list, but I thought you might find this interesting.


3 posted on 11/03/2015 7:52:53 AM PST by Ellendra (Those who kill without reason cannot be reasoned with.)
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To: Steely Tom

Usually, the “game-changer” stories are so early in the testing that most of the results are still hypothetical. This one has been approved, which means it’s gotten through all that testing already.


4 posted on 11/03/2015 7:54:38 AM PST by Ellendra (Those who kill without reason cannot be reasoned with.)
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To: Tired of Taxes

Ping..


5 posted on 11/03/2015 7:57:21 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: Steely Tom
These cancer “game-changer” therapy stories come up once or twice a year. Usually, they’re not heard from again.

Precisely! I'm dubious as to whether this will be effective against cancer, but it looks very promising for keeping the grant money flowing.

6 posted on 11/03/2015 7:57:31 AM PST by The Sons of Liberty (Politicians should be forced to wear the logos of the special interest groups they are beholden to.)
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To: Steely Tom

Not called the Krippin Virus I hope...


7 posted on 11/03/2015 7:59:27 AM PST by Resolute Conservative
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To: The Sons of Liberty

That’s all ok, just keep the hope alive and that too encourages others to keep researching their new ideas....all for God’s greater glory, and showing us just what a tremendous feat life creation truly is and each day’s survival as such a complex blessing.

Or a frozen asteroid got warmed in our atmosphere and left something of a cell.


8 posted on 11/03/2015 8:13:30 AM PST by If You Want It Fixed - Fix It
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To: Ellendra

If it does work, it’ll be like the new Hep C cure... free if you’re on welfare, otherwise out of reach because the treatment costs $80K and insurance companies don’t cover it.


9 posted on 11/03/2015 8:17:47 AM PST by Cementjungle
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To: Ellendra

I did a little looking at T-VEC; it’s a treatment, not a cure. It’s an improvement, not a panacea. It does, however, open a door to new research, that is, convincing viruses to help us out, rather than attack us.


10 posted on 11/03/2015 8:30:48 AM PST by sima_yi ( Reporting live from the far North)
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To: Ellendra

Praying that the trials are successful.


11 posted on 11/03/2015 8:35:46 AM PST by Blood of Tyrants (There's a right to gay marriage in the Constitution but there is no right of an unborn baby to life.)
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To: Ellendra; Tired of Taxes
Russell is hopeful that Imlygic represents "a first step in the direction of a complete change in the game" in how we treat cancer. "We can't prematurely claim that we've achieved our ultimate goal, because we haven't; this really is a single step along that path," he said. "But it's a very important and very significant step."

It's designed to be injected into a tumor. This doesn't seem feasible for each and every cancer, but this does seem to me to be a major advance in cancer treatment.

12 posted on 11/03/2015 8:40:31 AM PST by BykrBayb (Put a fork in Jeb. He'd want it that way. ~ Þ)
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To: lonevoice

Here is an article on that very promising melanoma treatment.


13 posted on 11/03/2015 8:51:14 AM PST by Pride in the USA
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To: Steely Tom

certain forms are. generally the child leukemias. otherwise stats havent changed that much for those doing the traditional chemo/radiation treatments. the “new” therapies actually are following the type of treatments alternative med using ntural compounds and approaches that targetonly the cancer and boost’the immune system.

chemo and radiation shoot the hostages and the terrorists and hope the hostages survive and no terrorists survive, which they always do, and then they come back stronger and more aggressive because the immune system is so much weaker.


14 posted on 11/03/2015 8:58:16 AM PST by Secret Agent Man (Gone Galt; Not averse to Going Bronson.)
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To: Ellendra

The treatment, which is called T-VEC (for talimogene laherparepvec) but will be sold under the brand name Imlygic, uses a modified virus to hunt cancer cells in what experts said was an important and significant step in the battle against the deadly disease.

It works by introducing a specially modified form of the herpes virus by injection directly into a tumour – specifically skin cancer, the indication for which the drug has been cleared for use.

It was developed by the Massachusetts-based biotech company BioVex, which was acquired in 2011 by biotech behemoth Amgen for $1bn. The genetic code of the virus – which was originally taken from the cold sore of a BioVex employee – has been modified so it can kill only cancer cells.


15 posted on 11/03/2015 8:58:41 AM PST by sefarkas (Why vote Democrat Lite?)
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To: Secret Agent Man

Better diagnostic tools have a lot to do with improved outcomes, as I can attest from personal experience.


16 posted on 11/03/2015 9:00:15 AM PST by Steely Tom (Vote GOP: A Slower Handbasket)
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To: Ellendra

pfl


17 posted on 11/03/2015 9:03:27 AM PST by MomwithHope (Please support efforts in your state for an Article 5 convention.)
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To: Ellendra

I hope it works....but it sounds like the beginning of “I Am Legend”.


18 posted on 11/03/2015 9:05:01 AM PST by DouglasKC (I'm pro-choice when it comes to lion killing....)
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To: Ellendra

This may be a game changer since it has been approved. So it has withstood Phase 1 to x trials.

The hope is that even though one tumor gets the injection, the patient’s immune system is triggered to knock out the cancer, all over. Not every person will get this reaction, but it is not unprecedented in medicine. Simple radiation of a single lesion has induced immune response in rare cases. A drug called Xofigo, a radium to prostate cancer in bone, has been known to trigger immune response.

Much of the immune drug development begin with melanoma patients. However, it is likely applicable to prostate and breast cases as well. Look for YERVOY, OPDIVO, KEYTRUDA, ZELBORAF, KEYTRUDA, ZELBORAF in the approval pipeline.


19 posted on 11/03/2015 9:11:06 AM PST by cicero2k
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To: BykrBayb

It’s designed to be injected into a tumor. This doesn’t seem feasible for each and every cancer, but this does seem to me to be a major advance in cancer treatment.

...

Some systemic effects have been observed, plus some doctors may choose to use it off label. The downside is that during tests this therapy only showed a life extension of five months. It’s a start in the right direction I think.


20 posted on 11/03/2015 9:15:44 AM PST by Moonman62 (The US has become a government with a country, rather than a country with a government.)
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