I don't think anyone is going to try to blow them out with a 30.06 or even a .22, although I'm sure someone will try.
But I guarantee that a 3 inch magnum #4 turkey load thru a full choke barrel will take it down and without a whole lot of worry about collateral damage.
I will not tolerate a drone flying over my property and if I see it, it will die.
Period.
And I don't give a damn who it belongs to.