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When Is Proton Beam Therapy Worthwhile? (Kennedy)
NPR ^ | 8/27/09 | Richard Knox

Posted on 08/27/2009 12:56:32 PM PDT by Drango

By Richard Knox

In his full-bore battle against brain cancer, Sen. Edward M. Kennedy resorted to treatment many consider experimental -- proton beam radiation therapy.

Sen. Kennedy returns to Senate last year after treatment for brain cancer.

Medicare pays for it. But his death leaves open a slew of questions about the costly treatment, which delivers high doses of radiation to tumor cells while largely sparing healthy tissue from damage.

Did it do him any good? Should Medicare (or private insurers) pay for the unproven treatment? And most politically fraught, should Kennedy's legacy issue -- universal health care -- include a mechanism for sorting out what new treatments are worth paying for, and when?

Britain's National Health Service has such a mechanism. It's known as NICE -- the National Institute for Health and Clinical Excellence.

Dr. Fergus Macbeth is director of NICE's Center for Clinical Practice and a specialist in radiation therapy for cancer. He says if Kennedy had been a patient in Britain's National Health Service "he wouldn't get proton beam therapy. And there's absolutely no evidence that proton beam therapy provides any additional benefit. It's not a wise use of your resources."

The NHS will pay for proton beam therapy only in cases where there's evidence of benefit -- patients with cancers in the base of the brain, for instance, or the back of the eye. The National Health Service currently pays for these patients to go abroad -- sometimes to US centers that have proton accelerators, which cost about $150 million to construct. But soon the United Kingdom will build a couple of facilities of its own.

The US has only a handful. One of them, at M.D. Anderson Cancer Center in Houston, doesn't use it to treat brain cancers like Kennedy's, advanced glioblastoma. Dr. James Cox, director of radiation oncology, says specialists there are "pursuing other strategies."

The main reason is that glioblastomas are highly resistant to radiation. " There's hardly any other cancer in the body that's so resistant," Cox says.

In the end, the proton beam therapy Kennedy got at Massachusetts General Hospital may not have bought him more life, if any. Cox says the reason some specialists use it for glioblastoma, at this point, is not to extend life. They hope to stave off some of the cancer's effects without the side effects of conventional radiotherapy, which damages normal brain tissue more than finely tuned proton beams do.

It's impossible to know if proton beam treatment gave Kennedy more months of quality life. But it didn't give him what he probably wanted most -- time to see Congress enact a universal health care plan.


TOPICS: Extended News; News/Current Events
KEYWORDS: braincancer; cancer; kennedy; nice; npr; protonbeam; radiation
Interesting.
1 posted on 08/27/2009 12:56:33 PM PDT by Drango
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To: Drango
It's known as NICE -- the National Institute for Health and Clinical Excellence.

Shouldn't the acronym be NIHCE?
2 posted on 08/27/2009 12:59:41 PM PDT by Sig Sauer P220 ("Peace" is that brief, glorious moment in history when everybody stands around reloading - Anonymous)
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To: Drango

Treatment for him, not for us. We can die quicker.


3 posted on 08/27/2009 1:04:28 PM PDT by Springman (Rest In Peace YaYa123)
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To: Drango
kennedy got the treatment others are denied under obamacare=romneycare=hillarycare.

congressmen and senators are better than other americans
who must gladly serve them as their slaves, with no
hope of treatment for them in the distant future.


4 posted on 08/27/2009 1:04:29 PM PDT by Diogenesis ("Those who go below the surface do so at their peril" - Oscar Wilde)
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To: Drango
How about the National Institute for Coordinated Experiments, with its symbol, a muscular male nude grasping a thunderbolt?

Cheers!

5 posted on 08/27/2009 1:08:11 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: Sig Sauer P220
Ole Teddy was done for when he was diagnosed with glioblastomas, had his health care dream been invoked last year or at some time in the past we'd be well past his funeral by now. Wonder why he didn't do the honorable thing and just go away and die without burdening the health care system, like the plan he supported wants everyone his age to do?
6 posted on 08/27/2009 1:09:08 PM PDT by pepperdog (As Israel goes, so goes America!)
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To: Drango

There is nothing experimental about Proton Therapy. It’s rare because the machines are expensive and specialized, but it does work and is an option at a number of centers including the mentioned MDA.


7 posted on 08/27/2009 1:11:38 PM PDT by Filo (Darwin was right!)
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To: Filo
I can't say. Here is what the expert quoted in the article said...

...And there's absolutely no evidence that proton beam therapy provides any additional benefit...

8 posted on 08/27/2009 1:14:48 PM PDT by Drango (A liberal's compassion is limited only by the size of someone else's wallet.)
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To: Drango

I think that they should have balanced all the harm he has done this coutry against the good he did it and, following a Zeke Emanuel concept, not allowed him such expensive treatment.


9 posted on 08/27/2009 1:23:01 PM PDT by AmericanVictory (Should we be more like them or they more like we used to be?)
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To: Drango
I can't say. Here is what the expert quoted in the article said...

...And there's absolutely no evidence that proton beam therapy provides any additional benefit...

In the context of this type of cancer that might be true.

Overall it is not.

10 posted on 08/27/2009 1:27:42 PM PDT by Filo (Darwin was right!)
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To: Filo
I work for the company that made the Proton Beam Accelerator. In fact, I have serviced the machine at MD Anderson and have gone over to Israel and worked on the machine there - it does save lives!
11 posted on 08/27/2009 1:41:42 PM PDT by qwicwted
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To: qwicwted

Here is the website for my company which has more info. http://www.accsys.com/


12 posted on 08/27/2009 1:43:17 PM PDT by qwicwted
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To: Filo
In the context of this type of cancer that might be true. Overall it is not.

My mother died of glioblastoma multiforme. She lived 3 months after surgery. Any brain cancer beginning with glio is very bad news indeed. Glioblastoma spreads rapidly and is resistant to almost any treatment.

There was some excitement years ago about a man with glioblastoma who was treated with direct heat to the cancer. At one point the docs thought they had him cured, but I know nothing further about this. If it had been successful ultimately I would think research would be concentrating on heat treatment. And it isn't.

13 posted on 08/27/2009 1:58:39 PM PDT by Ole Okie (American)
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To: Drango
Here is another picture of Teddy that some of you (may) recognize. Please identify this picture for those who have no clue as to it's Teddy Like Appearance. butt plug
14 posted on 08/27/2009 2:16:30 PM PDT by jongaltsr (Hope to See ya in Galt's Gulch.)
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