Whoever loses this time, whether it be Obama or Hillary, will be back in 2012 to challenge President McCain.
I doubt McCain would run for a second term.
I don't know about Hillary. If she looks like THIS now:
Can you imagine what she'll look like in 4 years? She ain't a fine wine...
Nope. If McCain wins neither one of these jerks wil be back in 2012. The party pro's will reassert control and, the voters having cleaned their house for them, will nominate some conventional moderate candidate who has a chance to win. This year is the hardcore Left's big chance. The alignment won't happen again for 20 years or more.