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Screening with a PSA test has a small impact on prostate cancer deaths but leads to overdiagnosis, finds study
Cancer Research UK ^ | APRIL 6, 2024 | Cancer Research UK

Posted on 04/07/2024 11:43:00 AM PDT by george76

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1 posted on 04/07/2024 11:43:00 AM PDT by george76
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To: george76

The results of the trial show that an estimated 1 in 6 cancers found by the single PSA screening were overdiagnosed.


“In a race it has long been known that one horse will beat another. But which one? differences are crucial.”

Lazarus Long


2 posted on 04/07/2024 11:47:33 AM PDT by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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To: george76

You know your body best?
Yeah but I knew lots of people with no symptoms until it had spread.
They say 1 in 6 cancer diagnosed were wrong. I’d rather not be one of the 5 without the test.


3 posted on 04/07/2024 11:50:30 AM PDT by Williams (Stop Tolerating The Intolerant)
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To: PeterPrinciple
Lazarus Long,
a fictional character featured in a number of science fiction novels by Robert A. Heinlein. Born in 1912 in the third generation of a selective breeding experiment run by the Ira Howard Foundation, Lazarus (birth name Woodrow Wilson Smith) becomes unusually long-lived, living well over two thousand years with the aid of occasional rejuvenation treatments.

Subtle hint for those uninitiated.

4 posted on 04/07/2024 11:56:28 AM PDT by higgmeister (In the Shadow of The Big Chicken! )
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To: george76

https://www.healthday.com/health-news/men-health/psa-test-a-thing-of-the-past-518850.html

https://go.gale.com/ps/i.do?id=GALE%7CA169431242&sid=sitemap&v=2.1&it=r&p=HRCA&sw=w&userGroupName=anon%7Ea26ca40b&aty=open-web-entry

“The prostate-specific antigen (PSA) test is not reliable as a screening tool for cancer, Thomas A. Stamey, M.D., of Stanford University, who first developed the test in 1987, says in the October issue of the Journal of Urology.”


5 posted on 04/07/2024 12:00:43 PM PDT by hecticskeptic
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To: george76

OK, so what do we do? I get bloodwork done every year for my thyroid and they always run a PSA test.


6 posted on 04/07/2024 12:15:52 PM PDT by jeffc (Resident of the free State of Florida)
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To: hecticskeptic

I don’t know anyone who would rely on PSA testing as their sole source for a cancer diagnosis, but - depending on the results, especially comparing more than one test (i.e., PSA velocity) - it’s certainly a useful indicator for further investigation.


7 posted on 04/07/2024 12:21:17 PM PDT by Magic Fingers (Political correctness mutates in order to remain virulent.)
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To: jeffc

You do this:

https://freerepublic.com/focus/f-chat/4229371/posts


8 posted on 04/07/2024 12:23:57 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: george76

I knew it.

Best thing guys can do is take all necessary action to eliminate inflammation.


9 posted on 04/07/2024 12:31:36 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: ConservativeMind
Thanks. Scary, but thanks. I'm 68 and the PSA hasn't come back positive... yet. No male in my family history had prostate cancer, or any cancer (except my Dad's brother - who died of skin cancer).

I have a good doctor and good insurance (Medicare Advantage!). Even so, at my age, I gotta' watch everything.

10 posted on 04/07/2024 12:34:13 PM PDT by jeffc (Resident of the free State of Florida)
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To: george76

The VA started the PSA tests every 5 years or so when I was about 40 due to my previous AO exposure. When I was 60, I wanted to get a life insurance policy for my new family.

USAA would insure me, but they doubled the premium because my PSA was around 5 or 6 by then. Over the next 10 years it continued to go up with doing yearly or so PSA’s, and a few MRI’s and biopsies and it got to 20 when I was 70.

The VA and I agreed it was probably time to do something so I did four months of radiation treatments, and the PSA is now down to 0.15 and they will do something when it comes back, but something else may kill me before then. I did have some side effects from the radiation but nothing to serious...


11 posted on 04/07/2024 12:36:13 PM PDT by montanajoe ( )
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To: Magic Fingers
it’s certainly a useful indicator for further investigation.

I agree. I'm a prostate cancer "survivor". First it was the finger up the bum, then a PSA, then a biopsy. Stage 1. Radiation.

Today (10 years later) I am sure there are CT scans etc. But for a starting point, the good old PSA does the trick. Ignorance of symptoms is not.

12 posted on 04/07/2024 1:00:18 PM PDT by llevrok (“In a time of deceit telling, the truth is a revolutionary act.” ― George Orwell)
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To: george76

Should a trans man get a PSA test or a pregnancy test? And is a trans man really a woman or really a man? I am having a hard time keeping all of this “straight”, so to speak.


13 posted on 04/07/2024 1:08:40 PM PDT by MtnClimber (For photos of scenery and wildlife, click on my screen name for my FR home page. More photos added.)
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To: MtnClimber

Oops, can you say “straight” anymore?


14 posted on 04/07/2024 1:09:33 PM PDT by MtnClimber (For photos of scenery and wildlife, click on my screen name for my FR home page. More photos added.)
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To: jeffc

> OK, so what do we do?

Prostate MRI.


15 posted on 04/07/2024 1:17:37 PM PDT by old-ager
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To: george76

My doctor has never ordered a PSA test nor has he ever stuck his finger up my bum to see if my prostate is enlarged. I do sometimes have a bit of trouble urinating. But not sure if the PSA is worth it.


16 posted on 04/07/2024 1:20:27 PM PDT by jimwatx
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To: MtnClimber

When you read trans, substitute fake, and it will help you sort out whether someone is really male or really female. You can’t change your DNA, no matter what you try to do to your body to fake out yourself or others.


17 posted on 04/07/2024 1:23:02 PM PDT by FamiliarFace (I got my own way of livin' But everything gets done With a southern accent Where I come from. TPetty)
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To: jeffc
Even so, at my age, I gotta' watch everything.

If you live long enough, you're bound to die of something.

Seriously, though, a PSA test every year or two isn't a bad idea. Just don't think that an elevated PSA is an automatic prostate cancer death sentence, especially from a single test. It's more important to watch for trends.

I'm about your age, and prostate cancer definitely runs in my family. So far I've been lucky.

18 posted on 04/07/2024 1:32:24 PM PDT by HartleyMBaldwin
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To: jimwatx

It’s amazing that there seems to be no simple noninvasive or minimally invasive screening for such a significant type of cancer. It’s almost as if all the money going to other stuff.


19 posted on 04/07/2024 2:01:07 PM PDT by John Milner (Marching for Peace is like breathing for food.)
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To: jimwatx

For me, a routine blood workup prior to elective surgery came back with an elevated PSA.

Doc recommended a urologist who examined me, and then scheduled the MRI.

The MRI showed i most likely had cancer and then the doc ordered a needle biopsy.

Net: I did indeed have cancer and went through radiation to get rid of it.

5 1/2 years cancer free.

What this adds up to is that a PSA test does NOT indicate or diagnose cancer but follow on testing does.

Glad I watched my PSA. You should too.


20 posted on 04/07/2024 2:14:31 PM PDT by Blueflag
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