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Goodbye Cigarettes – Scientists Discover Potential Treatment for Nicotine Dependence
Scitech Daily ^ | OCTOBER 5, 2023 | By UNIVERSITY OF MISSOURI-COLUMBIA

Posted on 10/05/2023 11:40:19 AM PDT by Red Badger

Researchers found that theta-burst transcranial magnetic stimulation (TBS) can improve self-control, resulting in reduced cigarette cravings and decreased smoking. The study revealed that people with nicotine dependence show different brain structures and functions, with these differences possibly affecting their inhibitory control, making it harder to resist the urge to smoke.

Theta-burst transcranial magnetic stimulation treatment could reduce cigarette cravings. A recent study from the University of Missouri School of Medicine indicates a potential alternative method to address cigarette cravings.

The research demonstrates that by using theta-burst transcranial magnetic stimulation (TBS) – powerful and quickly changing magnetic pulses that influence brain activity – individuals may experience enhanced self-control, diminished cravings, and subsequently, decreased cigarette consumption.

People with nicotine dependence tend to have significant structural and functional differences in the brain, compared to healthy non-smokers. Smoking cigarettes has been shown to be associated with less grey matter, which means they have fewer neurons and other cells in the brain.

Research suggests these differences may affect inhibitory control (IC), which is our control over automatic urges and response to stimuli – what enables humans to stop an impulsive reaction to something.

“Having difficulties with IC may make it harder to avoid smoking when the urge arises, in response to all the cues and contexts in the environment that trigger the behavior to light a cigarette,” said lead author Brett Froeliger, PhD, professor of Psychiatry.

TBS refers to when magnetic pulses are applied to the brain in bursts of three and come in two forms: continuous TBS (cTBS) and intermittent TBS (iTBS). cTBS consists of applying these three bursts repeatedly for 40 seconds, whereas iTBS applies the same number of pulses irregularly for more than 190 seconds.

Magnetic stimulation has been used to treat other mental illnesses and disorders. cTBS has been experimentally tested to treat generalized anxiety disorder, whereas iTBS to the left dorsolateral prefrontal cortex – a part of your brain responsible for cognitive processes – is FDA-approved for treating major depressive disorder.

The study involved 37 participants, mostly in their late 40’s, and examined the effects of both cTBS and iTBS to the right inferior frontal gyrus, a brain region heavily involved with IC. Researchers found that cTBS improved IC, whereas both cTBS and iTBS reduced cravings and, subsequently, smoking.

“Identifying treatments that improve IC may help reduce smoking and can potentially help with preventing relapse following when a person attempts to quit smoking,” Froeliger said. “Treatments that improve IC may also help disrupt the cycle of drug use among individuals with other substance use disorders; however, further research is needed to examine the clinical value of TBS for treating substance use disorders.”

Reference:

“Effects of Hyperdirect Pathway Theta-Burst Transcranial Magnetic Stimulation on Inhibitory Control, Craving, and Smoking in Adults with Nicotine Dependence: A Double-Blind Randomized Crossover Trial” by Spencer Upton, Alexander A. Brown, Muaid Ithman, Roger Newman-Norlund, Greg Sahlem, Jim J. Prisciandaro, Erin A. McClure and Brett Froeliger, 9 August 2023, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

DOI: 10.1016/j.bpsc.2023.07.014


TOPICS: Agriculture; Business/Economy; Health/Medicine; Military/Veterans
KEYWORDS: smoking; smokingcessation; tbs; tobacco
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To: Red Badger

I’d be a basket case!! lol...


21 posted on 10/05/2023 1:27:04 PM PDT by sit-rep
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To: fretzer

I’l try!... maybe next week!!


22 posted on 10/05/2023 1:27:31 PM PDT by sit-rep
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To: peggybac

I started smoking at $.50 a pack!


23 posted on 10/05/2023 1:28:45 PM PDT by sit-rep
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To: Big Red Badger

I see the smoke shops advertising $5.60 a pack for off brands... but I’m not sure if thats actually tobacco or camel dung!!


24 posted on 10/05/2023 1:30:17 PM PDT by sit-rep
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To: Mr. K
All those nicotine patches do is prolong the withdrawals so DON’T USE THEM.

Different things work for different people. My sister smoked from the age of 10 until 30. Nothinv worked until the patch. That was over 30 years ago.
25 posted on 10/05/2023 1:35:06 PM PDT by Dr. Sivana ("If you can’t say something nice . . . say the Rosary." [Red Badger])
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To: sit-rep

I was Marlboro Red box but Senaca Red
are a bit harsher but a third the cost...
Posted advice is get hooked on ZANAX.
sometimes I don’t know


26 posted on 10/05/2023 1:42:28 PM PDT by Big Red Badger (The Truman Show)
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To: Red Badger

A new vaccine? /s


27 posted on 10/05/2023 1:56:57 PM PDT by TribalPrincess2U (MURDER IS MYRDER)
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To: sit-rep

>I’l try!... maybe next week!!

That’s not how “cold turkey” works :)


28 posted on 10/05/2023 2:10:32 PM PDT by fretzer
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To: Red Badger

Smokers are like alcoholics they can’t stand to see someone else quit.


29 posted on 10/05/2023 3:07:05 PM PDT by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
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To: sit-rep

Yeah, I think I did too. I loved smoking but knew I had to quit. I’m so glad I did.


30 posted on 10/05/2023 4:10:53 PM PDT by peggybac (My will is what I wanted. God's will is what I got.)
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To: tet68

Exactly!


31 posted on 10/05/2023 4:11:57 PM PDT by peggybac (My will is what I wanted. God's will is what I got.)
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To: Red Badger

Government ain’t gonna like losing all that money


32 posted on 10/05/2023 4:13:15 PM PDT by Organic Panic (Democrats. Memories as short as Joe Biden's eyes)
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To: sit-rep

Started smoking at age 13, quit at age 63, now I’m 78. Two packs a day for 50 years. If I can do it anybody can.

Best of luck to you friend.


33 posted on 10/05/2023 5:34:40 PM PDT by Graybeard58 (There are only two sexes but there are 57 different types of queers.)
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To: keats5

How does it work for ice cream addicts?
That’s my problem.

~~~~~~~~~~~~~~~~~~~~~

Oh, oh, oh Ozempic


34 posted on 10/05/2023 5:38:18 PM PDT by Graybeard58 (There are only two sexes but there are 57 different types of queers.)
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To: Graybeard58

I started at 12...(Blame the parents! lol) and just turned 60. It’s time I try I reckon...


35 posted on 10/05/2023 5:41:30 PM PDT by sit-rep
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To: Hot Tabasco

Couldn’t hurt!....................


36 posted on 10/06/2023 5:04:50 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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