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High risk of severe infections found among individuals with nonalcoholic fatty liver disease (One extra serious infection per six people with fatty liver)
Medical Xpress / Karolinska Institutet / Clinical Gastroenterology and Hepatology ^ | May 29, 2023 | Fahim Ebrahimi et al

Posted on 05/30/2023 1:44:36 PM PDT by ConservativeMind

In a study involving more than 12,000 individuals with nonalcoholic fatty liver disease (NAFLD), researchers found a significantly increased risk of severe infections requiring hospital admission.

NAFLD is considered a manifestation of the metabolic syndrome in the liver and with the global rise in obesity, NAFLD has emerged as the most common chronic liver disease affecting around one quarter of all adults worldwide. It has also become the fastest growing cause of end-stage liver disease, primary liver cancer and liver transplantation.

In a study (the ESPRESSO study) involving 12,133 individuals with biopsy-proven NAFLD, and 57,516 matched controls from the general population, NAFLD was associated with a 71% higher risk for severe infections requiring hospital admission.

The researchers were intrigued by previous experimental studies that suggested that NAFLD is associated with impaired function of several immune cells which may lead to higher susceptibility towards various viral, bacterial, and fungal infections. "The liver plays a significant role in the human immune system with immune cells, such as macrophages (Kupffer cells) and lymphocytes, constituting up to 20% of all liver cells," adds Dr. Ebrahimi.

"We were surprised to find that the risk of severe infections was increased even in people with simple fatty liver disease without evidence of any liver inflammation or fibrosis. However, when individuals had evidence of the inflammatory subtype nonalcoholic steatohepatitis (NASH), or had developed fibrosis, they were at even higher risks with the highest risks among those with cirrhosis."

"The absolute risk difference at 20 years after NAFLD diagnosis was 17.3%, equal to one extra severe infection in every six patients with NAFLD, therefore, our findings underline the importance of early diagnosis and treatment to reverse the disease at all stages," says Jonas F Ludvigsson,

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: fattyliverdiesease; nafld
It is hard to know you have a fatty liver without a scan of some sort, but if you have metabolic syndrome, you likely have a fatty liver.

You can reverse fatty liver by losing enough fat to get below about 15% fat of your body weight. However, a supplement, Pantethine, was found to reverse fatty liver in over 50% of people in six months, and this was a study I put up a while back.

1 posted on 05/30/2023 1:44:36 PM PDT by ConservativeMind
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To: ConservativeMind

Pantethine study:

https://freerepublic.com/focus/f-chat/4008349/posts


2 posted on 05/30/2023 1:44:53 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

3 posted on 05/30/2023 1:45:23 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Yet another condition that Ivermectin treats/cures.

https://pubmed.ncbi.nlm.nih.gov/30738135

https://www.mdpi.com/1422-0067/23/24/16043

https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=2825&context=dissertations_2

List of places to buy pill-form IVM, no Rx required:

https://patriots.win/p/16bP7guA5N/sources-for-ivermectin—hcq-anti


4 posted on 05/30/2023 1:50:15 PM PDT by Non-Compliant_Deplorable
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To: ConservativeMind

I am currently doing this right now. I have a doctors visit in a few months and I’ll let you know the result of my blood workup.


5 posted on 05/30/2023 2:13:50 PM PDT by frogjerk (More people have died trusting the government than not trusting the government.)
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To: frogjerk

You won’t know if your fatty liver resolved from blood tests, unfortunately.


6 posted on 05/30/2023 5:44:23 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I know. But my liver enzymes should not be elevated. I would need another biopsy which is a risky procedure.


7 posted on 05/31/2023 1:39:33 PM PDT by frogjerk (More people have died trusting the government than not trusting the government.)
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To: frogjerk

No, and ultrasound, CT, or MRI can all see the fat.


8 posted on 05/31/2023 1:56:41 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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