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Polycyclic aromatic hydrocarbons strongly linked to raised rheumatoid arthritis risk (Smoking alone not strictly associated)
Medical Xpress / British Medical Journal / BMJ Open ^ | May 9, 2023 | Michelle Beidelschies et al

Posted on 05/10/2023 10:12:45 AM PDT by ConservativeMind

The amount of environmental exposure to polycyclic aromatic hydrocarbons, or PAH for short, is strongly linked to a person's risk of developing rheumatoid arthritis, suggests research.

These chemicals, formed from the burning of coal, oil, gas, wood, or tobacco as well as the flame grilling of meat and other foods, also seem to account for most of smoking's impact on risk of the disease, the findings indicate.

The researchers drew on the U.S. National Health and Nutrition Examination Survey (NHANES) between 2007 and 2016.

NHANES evaluates a wide variety of toxicants, along with data related to health, nutrition, behaviors and the environment.

The study included 21,987 adults, 1,418 of whom had rheumatoid arthritis and 20,569 of whom didn't. Blood and urine samples were taken to measure the total amount of PAH (7,090 participants), PHTHTEs (7,024), and VOCs (7,129) in the body.

The odds of rheumatoid arthritis were highest among those in the top 25% of bodily PAH levels, irrespective of whether or not they were former or current smokers.

After accounting for potentially influential factors, including dietary fiber intake, physical activity, smoking, household income, educational attainment, age, sex, and weight (BMI), only one PAH—1-hydroxynaphthalene—was strongly associated with higher odds (80%) of the disease.

PHTHTE and VOC metabolites weren't associated with heightened risk after accounting for potentially influential factors.

Somewhat surprisingly, however, smoking wasn't associated with heightened rheumatoid arthritis risk either, after accounting for PAH levels in the body.

And further analysis to separate out the influences of PAH and smoking showed that bodily PAH level accounted for 90% of the total effect of smoking on rheumatoid arthritis risk.

This is an observational study, and as such, can't determine cause. And the researchers acknowledge various limitations to their findings, including that measurements of environmental toxicants in fat (adipose) tissue weren't available.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: 2ndhandsmoking; arthritis; cigarettes; diet; environmental; rheumatoidarthritis; smoking
Smoking was NOT associated with rheumatoid arthritis. Instead, it was the total burden of 1-hydroxynaphthalene, which smoking and all the other sources, appear to create.
1 posted on 05/10/2023 10:12:45 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 05/10/2023 10:13:13 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Does that mean no more roscato wine for me?


3 posted on 05/10/2023 10:17:51 AM PDT by entropy12 (Food is most popular anxiety drug, exercise is the least popular.)
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To: ConservativeMind

Bacon cooked on gas stoves!!

Ban bacon. Ban gas stoves. Ban cooking. Ban meat. Then all will be well.


4 posted on 05/10/2023 10:18:15 AM PDT by ProtectOurFreedom (I don’t like to think before I say something...I want to be just as surprised as everyone else…)
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To: ConservativeMind

Bye to all the grifters polyesters then. Vests at
chain stores.


5 posted on 05/10/2023 10:19:12 AM PDT by Varsity Flight ( "War by🙏🙏 the prophesies set before you." I Timothy 1:18. Nazarite prayer warriors. 10.5.6.5)
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To: ConservativeMind

My doctor told me and I tend to agree, that 95% of your health is related to your genes.

You can huff, you can puff, you can dance, you can prance... You can do anything you want to avoid the inevitable But it’s going to get you in the end.

Death! It happens not only to the best of us, but to all of us.

The best advice in the world... Look both ways before you cross the street. That has literally saved hundreds of millions of lives.


6 posted on 05/10/2023 10:33:54 AM PDT by jerod (Nazi's were essentially Socialist in Hugo Boss uniforms... Get over it!)
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To: ConservativeMind

My wife has RA. That’s why she sends ME outside to grill the steaks.

She’s always said “You can have my grilled steak when you pry it from my cold, dead arthritic hands.”. I love that woman.


7 posted on 05/10/2023 10:53:12 AM PDT by moovova ("The NEXT election is the most important election of our lifetimes!“ LOL...)
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To: ConservativeMind

1-hydroxynaphthalene (aka 1-Naphthol) is a biological metabolite of naphthalene-based moth balls when said moth ball fumes are absorbed by the human body ... it might therefore be expected that excessive exposure to moth balls could be an inducer of rheumatoid arthritis ...


8 posted on 05/10/2023 11:26:54 AM PDT by catnipman (In a post-covid world, ALL "science" is now political science: stolen elections have consequences)
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To: ConservativeMind

.


9 posted on 05/10/2023 11:33:16 AM PDT by sauropod (“If they don’t believe our lies, well, that’s just conspiracy theorist stuff, there.”)
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To: catnipman
it might therefore be expected that excessive exposure to moth balls could be an inducer of rheumatoid arthritis

Poor moths :-) My grandparents used mothballs in their clothing closet in Norfolk. I haven't been exposed to any more since Fall of 1963. I did a blood test in grad school that consisted of adding a reagent of fine teflon balls to a drop of blood on the test slide. The test works by teflon balls becoming coated with antigens and antibodies from the blood. If you have both, the teflon balls coagulate on the test slide. My fellow students were about 10 minutes ahead of me and nobody was getting any coagulation results. I did my own blood same. Rocked the slide 3 times to mix the blood/reagent. It hardened into a mass on the slide. That was at age 20 in grad school. It was clear that RA was already underway. 800 mg of ibuprofen daily has slowed the damage to my joints and tendons. At nearly 67, the ibuprofen is becoming less able to keep the inflammation under control.

10 posted on 05/10/2023 12:05:46 PM PDT by Myrddin
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To: ConservativeMind

Bullshit. My smoker crapped out before the virus and I had no issues.

Enter the virus, and I’m struggling with RA.

Serious grain of salt on a singular cause of RA - particularly as outlined in the paper - not under an umbrella of inflammation.


11 posted on 05/10/2023 12:46:22 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: ConservativeMind

Robert Yoho Butchered by Healthcare, Pharma, and Government Kindle about $5.00. Never trust Med Mags. It came out before Covid hit. His Subtack Surviving Healthcare https://robertyoho.substack.com/

He covers a wide variety of subjects including the covid scam.


12 posted on 05/10/2023 2:05:53 PM PDT by GailA (Constitution vs evil Treasonous political Apparatchiks, Constitutional Conservative.)
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To: ConservativeMind

Nothing on Marijuana smoke?

Chris Plante says DC evening air is saturated with it.


13 posted on 05/10/2023 2:29:37 PM PDT by Does so ( 🇺🇦...................."Who is Ray Epps?" should be overstamped on every piece of currency.)
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To: ConservativeMind

I think a lot more studies need to be done before I toss the patio grill out. Not gone happen.


14 posted on 05/10/2023 3:04:00 PM PDT by Delta 21 (MAGA Republican is my pronoun.)
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