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One-minute visual fixation can identify patients with schizophrenia
Medical Xpress / Chinese Academy of Sciences / Schizophrenia Bulletin ^ | April 25, 2023 | Liu Jia / Xu Liu et al

Posted on 05/01/2023 9:35:19 PM PDT by ConservativeMind

Researchers demonstrated spatial and temporal abnormalities of spontaneous fixational saccades and their correlates with positive and cognitive symptoms in schizophrenia, suggesting that fixational saccades are a promising and easily obtainable biomarker for cognitive and positive symptoms and for complementary diagnosis in schizophrenia.

Schizophrenia is a devastating heterogenous psychotic disorder characterized by debilitating positive symptoms, negative symptoms, and cognitive deficits. Positive symptoms include hallucinations, delusions, disorganized speech and bizarre behaviors. Negative symptoms constitute an absence of normal functioning.

Given the central importance of seeing to humans, visual fixation is a fundamental behavioral pattern that allows people to gather information and guide decision-making. During visual fixation, microsaccades and large saccades (macrosaccades) occur spontaneously and frequently. These fixational saccades are sensitive to the structural and functional alterations of the cortical-subcortical-cerebellar circuit, and are closely linked with cognitive processes. However, the performances of fixational saccades in patients with schizophrenia remain largely unexplored.

Researchers analyzed fixational saccades recorded from 140 drug-naïve patients with first-episode schizophrenia and 160 age-matched healthy subjects during ten separate six-second attempted fixations. They found that patients with schizophrenia exhibited significantly more vertical saccades and a greater vertical deviation of horizontal saccades. They also found that the fixational saccades, especially horizontal saccades, had longer durations, faster peak velocities, and larger amplitudes in patients than in controls.

Through careful measurements of the schizophrenia patient's cognitive capacities, researchers found that the longer duration of horizontal saccades was associated with lower cognitive performance, especially deficits in attention/vigilance and speed of processing, and that the greater vertical deviation of horizontal saccades was associated with more severe positive symptoms.

Based solely on the fixational eye movements recorded during a one-minute period, a simple machine-learning model classified patients and controls with an accuracy of 85%.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: schizophrenia
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In one minute with someone, you can have an 85% confidence that someone is truly schizophrenic.
1 posted on 05/01/2023 9:35:19 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 05/01/2023 9:35:56 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Or you can just ask if they are a registered Democrat.


3 posted on 05/01/2023 9:41:15 PM PDT by Skid289 (I’ve always been a Texan, it just took me 50 years to get here)
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To: ConservativeMind

You can’t prove it. I’m normal. Can’t you see that I’m normal?


4 posted on 05/01/2023 9:46:28 PM PDT by Jeff Chandler (THE ISSUE IS NEVER THE ISSUE. THE REVOLUTION IS THE ISSUE.)
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To: ConservativeMind

I may need a ‘translation’ of those first few sentences.
Or, I could just drive back here when I have more patience, and read it, glossary in hand.


5 posted on 05/01/2023 9:46:55 PM PDT by lee martell
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To: ConservativeMind
Saw schizophrenia in this guy in less time than that. Sorta have experience but you can see it in his eyes:

rhode-island-man-guilty-on-all-counts-in-kneeland-homicide

6 posted on 05/01/2023 9:57:33 PM PDT by Karliner (Heb 4:12 Rom 8:28 Rev 3, "...This is the end of the beginning." Churchill)
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To: ConservativeMind

7 posted on 05/01/2023 10:05:30 PM PDT by SpaceBar
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To: ConservativeMind

This idea reminds me of the tests for androids that were done in the movie “Blade Runner”.


8 posted on 05/01/2023 10:09:22 PM PDT by glorgau
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To: ConservativeMind

” debilitating positive symptoms, negative symptoms, and cognitive deficits”

But, don’t those positive and negative symptoms cancel each other?

Or, is that not how it works?


9 posted on 05/01/2023 10:11:43 PM PDT by doorgunner69 (Let's go Brandon)
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To: doorgunner69

Positive and negative symptoms in schizophrenia are perhaps different from what the names imply. Positive symptoms are those that are “added” compared to a normal person — such as hallucinations and extreme delusions. Negative symptoms are characteristics that exist in the normal person but are “subtracted” in schizophrenia, such as ability to feel pleasure (anhedonia).


10 posted on 05/01/2023 10:24:01 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: lee martell

Had to look up “saccade”

A saccade (/səˈkɑːd/ sə-KAHD, French for jerk) is a quick, simultaneous movement of both eyes between two or more phases of fixation in the same direction.[1] In contrast, in smooth pursuit movements, the eyes move smoothly instead of in jumps.

https://en.m.wikipedia.org/wiki/Saccade

So the article is talking about observing the eye movements of the patient.


11 posted on 05/01/2023 10:41:57 PM PDT by SauronOfMordor (The rot of all principle begins with a single compromise.)
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To: glorgau
This idea reminds me of the tests for androids that were done in the movie “Blade Runner”.

"Let me tell you about my mother!"

Regards,

12 posted on 05/01/2023 11:43:16 PM PDT by alexander_busek (Extraordinary claims require extraordinary evidence.)
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To: All

I hOp E TTTThE y dOn’T ThImmmnnnn,,,,,mmmmk I’m like

CrAzY

juSt cuz i DO thI sssssssssssssssssss

wiTh My eYeSSSSSSSSSSSSsSsSsSsSsSsSsSsSsS

anD stufFfF


13 posted on 05/02/2023 12:37:31 AM PDT by Peter ODonnell (In leftspeak, "disproven false claim" means fact. "Intolerance" means revulsion. "Progress" =failure)
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To: ConservativeMind

A test for the tranny crowd. It would ex6 a lot.


14 posted on 05/02/2023 3:33:28 AM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: Skid289

15 posted on 05/02/2023 4:01:21 AM PDT by Bratch
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To: glorgau
This idea reminds me of the tests for androids that were done in the movie “Blade Runner”.

Yeah, just ask them if they know what a tortoise is.

16 posted on 05/02/2023 5:21:43 AM PDT by T.B. Yoits
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To: ConservativeMind

I get that way when I look at boobies for too long.


17 posted on 05/02/2023 5:31:46 AM PDT by Delta 21 (MAGA Republican is my pronoun.)
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To: ConservativeMind; NobleFree

FTA:

“[Positive] symptoms include hallucinations, delusions, disorganized speech and bizarre behaviors.”
^

Schizophrenia can be induced among MARIJUANA users, and now that it’s nominally legal, even children and pets can be affected.

https://pubmed.ncbi.nlm.nih.gov/32839678/


18 posted on 05/02/2023 5:44:03 AM PDT by Does so ( 🇺🇦...................."Who is Ray Epps?" should be overstamped on every piece of currency.)
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To: ConservativeMind
Are you psychotic? Test your fixation below:


19 posted on 05/02/2023 5:47:36 AM PDT by Sirius Lee (They intend to murder us. Prep if you want to live and live like you are prepping for eternal life)
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To: ConservativeMind

So if I stare at a woman for over one minute, does that mean I’m schizophrenic or not?


20 posted on 05/02/2023 6:20:09 AM PDT by DannyTN
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