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Pungent ginger compound puts immune cells on heightened alert (+30% from 1 L of ginger tea)
Medical Xpress / Leibniz-Institut / Molecular Nutrition & Food Research ^ | Feb. 14, 2023 | Gaby Andersen et al

Posted on 02/15/2023 3:32:31 PM PST by ConservativeMind

Ginger has a reputation for stimulating the immune system. New results now support this thesis. In laboratory tests, small amounts of a pungent ginger constituent put white blood cells on heightened alert.

Whether as a medicinal plant or foodstuff, ginger is also becoming increasingly popular. However, the question arises as to whether normal consumption levels are sufficient to achieve health effects.

As the study shows, significant amounts of pungent ginger compounds enter the blood about 30 to 60 minutes after consuming one liter of ginger tea. By far the highest levels were achieved by [6]-gingerol, with plasma concentrations of approximately 7 to 17 micrograms per liter.

The pungent compound is known to exert its "taste" effect via the so-called TRPV1 receptor, an ion channel located on the surface of nerve cells that responds to painful heat stimuli as well as to pungent compounds from chili and ginger. Since some studies suggest that white blood cells also possess this receptor, the research team tested whether [6]-gingerol influences the activity of these immune cells.

In a first step, the team succeeded in detecting the receptor on neutrophil granulocytes. The research group also showed that even a very low concentration of almost 15 micrograms of [6]-gingerol per liter is sufficient to put the cells on heightened alert.

Thus, compared to control cells, the stimulated cells reacted about 30 percent more strongly to a peptide that simulates a bacterial infection.

"Thus, at least in experiments, very low [6]-gingerol concentrations are sufficient to affect the activity of immune cells via the TRPV1 receptor. In blood, these concentrations could theoretically be achieved by consuming about one liter of ginger tea," says Gaby Andersen.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: ginger; gingertea
If dealing with a bacterial infection, this seems a great addition.

If normally dealing with an autoimmune issue, it’s not clear this wouldn’t aggravate it so maybe one might need to reduce intake, then.

1 posted on 02/15/2023 3:32:31 PM PST by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

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2 posted on 02/15/2023 3:33:05 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

One liter of ginger tea. I would rather be sick


3 posted on 02/15/2023 3:34:04 PM PST by Fai Mao (Stop feeding the beast, and steal its food!)
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To: Fai Mao

Me too!!!


4 posted on 02/15/2023 3:44:00 PM PST by lizma2
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To: ConservativeMind

Now you know why Gingers have no souls.


5 posted on 02/15/2023 3:48:21 PM PST by dfwgator (Endut! Hoch Hech!)
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To: Fai Mao

How about crystallized ginger? It’s candy!


6 posted on 02/15/2023 3:59:24 PM PST by Pearls Before Swine
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To: ConservativeMind

Absolutely dislike ginger.

I like Maryanne


7 posted on 02/15/2023 4:00:45 PM PST by Vaquero (Don't pick a fight with an old guy. If he is too old to fight, he'll just kill you. )
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To: ConservativeMind

Taking anti-rejection drugs as I am, I should probably add ginger to my
DO NOT EAT list so it doesn’t cause me problems. I don’t know that it would, but ginger is something I rarely have anyway, except in oriental food.


8 posted on 02/15/2023 4:01:26 PM PST by telescope115 (My feet are on the ground, and my head is in the stars.)
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To: ConservativeMind

In Asia where I live, ginger tea is a standard remedy. At the first sign of symptoms, drink a cup of that powerful stuff, and enjoy being fully recovered the next day in most cases. I like how after clinically showing it gives a 30% immune system boost, this article concludes with ‘Nevertheless...’ blah blah.


9 posted on 02/15/2023 4:02:20 PM PST by Ragnar Danneskjöld
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To: Vaquero

RIP Racquel

10 posted on 02/15/2023 4:26:59 PM PST by grey_whiskers ( The opinions are solely those of the author and are subject to change without notice.)
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To: ConservativeMind

Ginger is also a natural anti nausea agent.


11 posted on 02/15/2023 5:18:36 PM PST by Blood of Tyrants (Blacks have placed stronger chains on themselves than the slave masters of old ever forged.)
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To: grey_whiskers

No nausea with that ginger!


12 posted on 02/15/2023 5:32:43 PM PST by Fresh Wind (The last remnants of the Old Republic have been swept away.)
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To: ConservativeMind

I use fresh cut ginger for upset stomach before anything else. Tums will kill ya!

Slice in a glass of cold water and sip. It won’t hurt to try it. Little at a time until you get your level.


13 posted on 02/15/2023 6:23:21 PM PST by TribalPrincess2U (D.I.S.T.R.A.C.T.I.O.N.S.)
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To: TribalPrincess2U

I wonder if Ginger would be hard on the stomach. I have acid problems. Not sure I could drink Ginger tea.


14 posted on 02/15/2023 7:25:32 PM PST by WVNan
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To: ConservativeMind

That’s why back in the 50s our moms and nans always gave us ginger ale when we were home sick with a cold.


15 posted on 02/15/2023 9:04:15 PM PST by Albion Wilde ("There is no good government at all & none possible."--Mark Twain)
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To: Albion Wilde

Re “...back in the 50s our moms and nans always gave us ginger ale when we were home sick with a cold” I remember getting it when sick, but connect it to curing upset stomach.

On further review, I think we had it in the house for company and the adult ‘Highballs’ ...

Do you know if what we can now buy in supermarkets has actual Ginger in it? What about “Ginger Beer”?


16 posted on 02/20/2023 5:06:59 AM PST by John Galt's cousin (Hey DeepStater, "You are NOT the boss of me, or US.")
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To: John Galt's cousin
On further review, I think we had it in the house for company and the adult ‘Highballs’ ...
Do you know if what we can now buy in supermarkets has actual Ginger in it? What about “Ginger Beer”?

LOL -- I remember the older generation talking about "highballs." Even when my aunties were in their 90s in the nursing home, they would have a highball every evening. Being southerners, this is pronounced "HAH bauw."

I do not know about today's ginger products, but I would recommend reading the label -- it should just say "ginger" in the ingredient list -- watch out for "artificial flavor(s)." It's a pretty difficult flavor to synthesize. And ginger is not rare; it is used plentifully in British, Chinese, Japanese, West Indies and African cultures. Our local Caribbean store and the Hispanic store always have a huge pile of raw ginger root and a wide variety of imported but affordable ginger products -- ginger teas, sodas, cookies, salad dressing, meat and fish rubs, etc.

I keep dried ginger powder for baking my gingersnaps, soft ginger cookies, ginger chocolate chip cookies (the best!), and gingerbread cakes; but I buy some fresh root for holiday baking, and keep some ginger root in the freezer. Using grated fresh root really punches up the flavor.

17 posted on 02/20/2023 9:10:21 AM PST by Albion Wilde ("There is no good government at all & none possible."--Mark Twain)
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