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Study explores effects of dietary choline deficiency on neurologic and system-wide health (90% of Americans don’t get enough)
Medical Xpress / Arizona State University / Aging Cell ^ | Jan. 17, 2023 | Nikhil Dave et al

Posted on 01/21/2023 12:42:34 PM PST by ConservativeMind

Choline, an essential nutrient found in foods including eggs, broccoli, beans, meat and poultry, is a vital ingredient for human health. A study explores how a deficiency of dietary choline adversely affects the body and may be a missing piece in the puzzle of Alzheimer's disease.

It's estimated that more than 90% of Americans are not meeting the recommended daily intake of choline. The current research suggests dietary choline deficiency can have profound negative effects on the heart, liver and other organs.

Lack of adequate choline is also linked with profound changes in the brain associated with Alzheimer's disease. These include pathologies implicated in the development of two classic hallmarks of the illness: amyloid plaques, which aggregate in the intercellular spaces between neurons; and tau tangles, which condense within bodies of neurons.

The research describes pathologies in normal mice deprived of dietary choline and in choline-deficient transgenic mice. In both cases, dietary choline deficiency results in liver damage, enlargement of the heart and neurologic alterations in AD mice, typically accompanying Alzheimer's disease and including increased levels of plaque-forming amyloid-beta protein and disease-linked alterations in tau protein.

Further, the study illustrates that choline deficiency in mice causes significant weight gain, alterations in glucose metabolism (which are tied to conditions such as diabetes), and deficits in motor skills.

Choline is needed to produce acetylcholine, a neurotransmitter that plays an essential role in memory, muscle control and mood. Choline also builds cell membranes and helps regulate gene expression. New lines of evidence imply that the established recommended daily intake of dietary choline for adult women (425mg/day) and adult men (550mg/day) may not be optimal for proper brain health and cognition. Additionally, Americans may not even be aware that dietary choline is required on a daily basis.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: alzheimers; choline; nutrition
Egg yolks have just under 150 mg of choline.

You can buy lecithin for a more potent dose of phosphatidyl choline.

1 posted on 01/21/2023 12:42:34 PM PST by ConservativeMind
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2 posted on 01/21/2023 12:43:37 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind
You can buy lecithin for a more potent dose of phosphatidyl choline.

In addition, lecithin is much better for you than morifat.

OK, I'll be serious. One of the reason staph is a problem is that the bacteria produces lecithinase, which breaks down the lecithin and makes it unusable in helping neurotransmission. Having probiotics build up the "good" gut bacteria is also a way of ensuring better choline absorption, I think.

3 posted on 01/21/2023 12:58:55 PM PST by chajin ("There is no other name under heaven given among people by which we must be saved." Acts 4:12)
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To: ConservativeMind

90% lacking...well...they’re all living so when does this make a difference....in year 10...or year 80?


4 posted on 01/21/2023 12:59:45 PM PST by Sacajaweau ( )
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To: ConservativeMind

eggs and meat...you said we shouldn’t be eating this stuff...


5 posted on 01/21/2023 1:00:46 PM PST by Sacajaweau ( )
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To: ConservativeMind

An ordinary diet gives you enough choline...so 90% makes no sense.


6 posted on 01/21/2023 1:03:24 PM PST by Sacajaweau ( )
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To: ConservativeMind
found in foods including eggs, broccoli, beans, meat and poultry

I'm probably okay. I eat plenty of eggs, meat, and poultry

7 posted on 01/21/2023 1:17:03 PM PST by Jeff Chandler (THE ISSUE IS NEVER THE ISSUE. THE REVOLUTION IS THE ISSUE.)
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To: Jeff Chandler

“found in foods including eggs, broccoli, beans, meat and poultry!”

My live in RN and head chef for 62+ years replaced broccoli with brussel sprouts and kale a few years ago.

Now, I can’t remember our neighbors’s last names or is that due to getting Covid this past Thanksgiving or being 84 or no broccoli?


8 posted on 01/21/2023 1:47:53 PM PST by Grampa Dave ((Truth is hate speech to those, who hate the truth!) (clintonh8r))
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To: ConservativeMind

You’re correct. Phosphatidylcholine is found in egg yolks. But egg production is a major driver of climate change.

If you eat eggs the sun will bake the Erf and the seas will boil. It’s true, Al Gore said so.

I wonder how much is in cricket protein powder or cockroach milk? Enough to make the WEF happy?


9 posted on 01/21/2023 2:10:00 PM PST by packagingguy
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