Posted on 10/13/2022 9:43:12 AM PDT by bitt
Covid-19 patients with a history of cardiovascular disease are at an increased risk of developing severe illness and could benefit most from the Covid-19 treatment Paxlovid – but there’s a catch.
Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease, including certain statins and heart failure therapies, a new paper warns.
The review paper, published Wednesday in the Journal of the American College of Cardiology, lists dozens of cardiovascular medications and whether they are safe to give along with Paxlovid or whether they could have interactions.
Some medications such as aspirin are safe to take with Paxlovid, according to the paper, but other drugs could have interactions, and therefore, their dosage should be adjusted or temporarily discontinued while a patient is taking Paxlovid.
When President Joe Biden tested positive for Covid-19 and started Paxlovid in July, his physician Dr. Kevin O’Connor temporarily took him off Crestor and Eliquis, two heart medications that the President takes for his pre-existing conditions. Doctors say there is no short-term risk to stopping these drugs.
The review paper says that interactions between Paxlovid and certain blood thinners can cause an increased risk of bleeding. Interactions between Paxlovid and some cholesterol medications such as statins can be toxic to the liver, and interactions between Paxlovid and certain blood pressure medications could cause low blood pressure, flushing and swelling.
(Excerpt) Read more at cnn.com ...
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Really?
Then why take them at all?
Except for the risk of stroke after stopping a blood-thinner suddenly. I know someone who was ordered to stop taking Eliquis ‘cold-turkey’ by a doctor. He had a stroke within 48 hours and died of a clot in his brain stem.
More “good news”...
“Then why take them at all?”
That would be a long-term risk.
Shudup.../S
The doctors should have said, “There is extremely low risk to stopping these drugs.”
Many interactions are caused by the fact that several medications are metabolized by the same enzymes in the body. Introducing a second drug which depends upon a given enzyme reduces the level of enzyme available for metabolizing the first drug.
Failure to be metabolized and removed from the body can cause the dosage in the blood to increase as if a higher amount of the drug had been taken.
My wife was recently given Paxlovid. Her blood pressure medication was reduced to one half the usual amount. Due to the expected slowing of the metabolizing of the blood pressure medication, it was expected that the level in her blood would increase maintaining the effectiveness of the drug.
I was considered for Paxlovid but wasn’t prescribed because I take a complicated array of drugs and that made management in the presence of Paxlovid too uncertain. If I had had more symptoms of Covid the decision might have been different.
Gotta love EUAs. My expectation is that these side effects are found before releasing it to the general populace.
I took Paxlovid and my doc did the same thing (short term cessation of Crestor). Frankly, I didn’t notice that it did any good (it still felt like the flu for 3 days and was then gone), but the Paxlovid has a side effect that makes your mouth taste like you swallowed a large bag of trash. Just gross.
A direct report to my daughter was given Paxlovid by her physician because this woman supposedly had Covid and has diabetes. After taking Paxlovid, this woman is having to use a walker and can barely see. There was a period of time where she could not walk at all. Currently, they have no idea if this is for life.
Beware of Paxlovid.
(((...Heh...)))
" Covid-19 patients with a history of cardiovascular disease are at an increased risk of developing severe illness
and could benefit most from the Covid-19 treatment Paxlovid – but there’s a catch.
Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease,
including certain statins and heart failure therapies, a new paper warns.
The review paper, published Wednesday in the Journal of the American College of Cardiology, lists dozens of cardiovascular medications
and whether they are safe to give along with Paxlovid or whether they could have interactions.
Some medications such as aspirin are safe to take with Paxlovid, according to the paper, but other drugs could have interactions, and therefore,
their dosage should be adjusted or temporarily discontinued while a patient is taking Paxlovid."
Bttt
Don’t forget the effects of grapefruit juice in this regard.
Seriously.
Crestor is to prevent early heart attack maybe due to high cholesterol.
Joe is either in his 80’s or close to them. So he is past the age for an early heart attack. Taking a Statin/Crestor at his age or my age is not really a wise move.
You are never too old to have a stroke. I’m on Eliquis 2x a day, and I don’t like not taking it. Strokes contributed to the death of my maternal granddad and his daughter, my mother.
My physician, at my request, reduced my Eliquis in half because I am now taking so many supplements that thin the blood.
She agreed.
That sounds like a good MD who listens to their patients.
That is a winning combo for the MD and patient!)
That sounds like a good MD who listens to their patients.
That is a winning combo for the MD and patient!)
My wife said she got a very bitter taste. She overcame it by sucking on very strong cough drops.
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