I used to hear that the average woman ‘lived longer’ than the average man because women have high levels of estrogen, whereas, the testosterone levels that make men male also tend to wear out certain organs faster; i.e. the heart.
Maybe that was just an Old Wive’s Tale.
Actually, there is a large cohort of individuals who live their entire lives possessing neither a xx chromosome, or an xy chromosome, but only a single x chromosome. They are all women, and they are described as suffering from “Turner’s syndrome.”
They have a variety of unusual, but sometimes quite subtle, symptoms. These range from infertility, being very short, having a high palate, ear issues, and moon shaped nails.
I had never heard that men can lose their y chromosome as they age, though.
Women live longer than men because men start accumulating iron earlier.