Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Increasing incidence of early-onset colorectal precancerous lesions in patients under age 50
Medical Xpress / The Mount Sinai Hospital / Gastroenterology ^ | Jan. 11, 2022 | Steven H. Itzkowitz, MD, FACP

Posted on 01/11/2022 12:02:15 PM PST by ConservativeMind

Researchers describe a troubling increase in early-onset colorectal cancer and precancerous polyps, based on a large, nationally representative study of patients under age 50 who underwent colonoscopy. It was the first large-scale study to look at precancerous polyps in this age group.

"We have known for many years that rates of colorectal cancer are rising in individuals younger than 50, prompting several medical organizations to recommend lowering the screening age from 50 to 45. What has been missing until now is confirmatory data of the prevalence of precancerous polyps in younger individuals. Because precancerous lesions are not reportable to regional or national health agencies, we have not had this degree of information to guide our recommendations. Our study provides an important piece of the puzzle and supports the recommendation changing the screening age to 45," says lead author Steven H. Itzkowitz, MD. "Our findings also suggest that messaging aimed at young individuals should begin in the years leading up to this new screening age. We know that most patients do not call their doctors on their 50th birthday to schedule a colonoscopy, so we will need to be diligent to reach this much younger cohort before they turn 45," says Dr. Itzkowitz.

Increasing age, being male and white, having a family history of colorectal cancer, and having had colonoscopies for reasons of bleeding or screening, were all associated with higher odds of advanced premalignant lesions (APLs) and colorectal cancer. Among patients aged 45-49, 32 percent had neoplasia (precancerous or cancerous lesions considered forerunners to colorectal cancer). Nearly 8 percent had APLs, and 0.58 percent had colorectal cancer.

Early-onset colorectal cancer accounts for approximately 12 percent of all colorectal cancer cases, with incidence increasing by 2.2 percent annually from 2012-2016, and mortality increasing by 1.3 percent per year from 2008-2017.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: colonoscopy; colorectalcancer; polyps
Navigation: use the links below to view more comments.
first previous 1-2021-4041-6061-76 next last
To: mass55th
For diabetics, they recommend Crystal Light to mix with the prep. The only flavor you can use is their lemonade mixture, because they tell you, no red liquid.

Yeah. I went with Gatorade Zero. A bit more "non-red" sugar free flavor options there and the bottle itself is perfectly 32oz. I settled on "white" Gatorade (not sure what the flavor is). I was supposed to do 8oz every 15 minutes for an hour to equal the 32, but I just basically downed the entire thing in the first 10-15 minutes.

I think my ability to seamlessly still suck down 10 beers on trivia night with the boys made the two 32oz bottles of gatorade seem like a cake-walk.

I'm 51 I'm sure I'll be a lot less glib about it when I'm doing it in my 70s (God-willing).
41 posted on 01/11/2022 1:13:13 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 36 | View Replies]

To: ConservativeMind

And you’ve got to beware. The one my buddy Darryl went to was strange. Before the exam, he gave him a prostate exam. It was just Darryl and the doctor in the room. Once the doctor put in the instrument, Darryl said it felt weird, and he started to worry. But the doctor put both hands on Darrel’s shoulders and assured him everything was good. But he always thought something about that particular visit wasn’t right...


42 posted on 01/11/2022 1:14:37 PM PST by Captainpaintball
[ Post Reply | Private Reply | To 1 | View Replies]

To: Vermont Lt; ConservativeMind

There’s a known correlation between meat & fat heavy diets and colorectal cancers. Far less common among vegetarians.

Non-vegetarians can improve their chances if cruciferous vegetables and mushrooms are a standard part of their diet.


43 posted on 01/11/2022 1:18:35 PM PST by Pelham (Q is short for quack )
[ Post Reply | Private Reply | To 34 | View Replies]

To: corkoman
EVERY histology report from a colonoscopy procedure will include the words "pre-cancerous" or "atipia"

Mine said "normal", "moderate sedation" and "no specimens collected". Said to return in 10 years.
44 posted on 01/11/2022 1:18:46 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 39 | View Replies]

To: Pelham
If you have a history of polyps or cancer in your family your doc would likely insist on a colonoscopy to get that remaining 2% covered but otherwise this test is the way to go.

I share your opinion.
45 posted on 01/11/2022 1:21:54 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 40 | View Replies]

To: mmichaels1970

Exact Sciences should offer us a gift for touting their test. We shouldn’t have to work for free.


46 posted on 01/11/2022 1:27:15 PM PST by Pelham (Q is short for quack )
[ Post Reply | Private Reply | To 45 | View Replies]

To: mmichaels1970
"A bit more "non-red" sugar free flavor options there and the bottle itself is perfectly 32oz."

I had to mix the Crystal Light with 64 ounces of water. The prep my doctors uses requires you to drink 64 ounces, not 32.

47 posted on 01/11/2022 1:28:36 PM PST by mass55th ("Courage is being scared to death, but saddling up anyway." ~~ John Wayne )
[ Post Reply | Private Reply | To 41 | View Replies]

To: Pelham
Exact Sciences should offer us a gift for touting their test. We shouldn’t have to work for free.

Lol...Not sure I'm interested in any "free samples" from them.
48 posted on 01/11/2022 1:30:03 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 46 | View Replies]

To: mass55th
The prep my doctors uses requires you to drink 64 ounces, not 32.

I had to do two bottles totaling 64oz. 32 at 6pm the night before and 32 4 hours prior to the procedure. I think each 32oz bottle had about 4 1/4 oz of Miralax. My grandson kicked in and lent me his baby-bottle to measure the Miralax.
49 posted on 01/11/2022 1:32:45 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 47 | View Replies]

To: mmichaels1970

Yeah we may want to tout some other kind of test before begging for free samples.


50 posted on 01/11/2022 1:33:29 PM PST by Pelham (Q is short for quack )
[ Post Reply | Private Reply | To 48 | View Replies]

To: refreshed

GMO crops, especially BT crops reduces cancers of the intestinal tract by reducing exposure to aflatoxin contamination caused by fungal pests, not to mention the reduced amount of pesticide uses in general.

You know the real cause of colorectal cancer they aren’t talking about is anal sex, which our pornified younger generations are practicing at a much higher rate than older generations (both men and women). I feel so sorry for them, frankly, they are being physically, mentally and spiritually damaged by the sick internet culture they immerse themselves in.


51 posted on 01/11/2022 1:35:10 PM PST by Valpal1
[ Post Reply | Private Reply | To 3 | View Replies]

To: mmichaels1970
"My grandson kicked in and lent me his baby-bottle to measure the Miralax."

My sons are in their 50's, and thankfully at 74, I don't have any grandkids to worry about growing up in what will soon be a communist 3rd world shit hole.

52 posted on 01/11/2022 1:37:37 PM PST by mass55th ("Courage is being scared to death, but saddling up anyway." ~~ John Wayne )
[ Post Reply | Private Reply | To 49 | View Replies]

To: mass55th
I don't have any grandkids to worry about growing up in what will soon be a communist 3rd world shit hole.

I hear that and do have those concerns. Although feeling his cheek against mine does tend to make communism (and all other stress and worries) completely disappear if only for a few seconds.
53 posted on 01/11/2022 1:45:08 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 52 | View Replies]

To: ConservativeMind

The last time that I ran the numbers, the probability of finding something (in an otherwise healthy person with no family history) was roughly the same as an ‘accident’ happening during the procedure (roughly 1% for both).

So, no thanks, I’ll play the odds here.


54 posted on 01/11/2022 2:03:24 PM PST by BobL (I shop at Walmart and eat at McDonald's, I just don't tell anyone, like most here.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: mmichaels1970

I hope you are able to enjoy him for many, many years, and that he has a long and happy, healthy, and fulfilling life.


55 posted on 01/11/2022 2:03:51 PM PST by mass55th ("Courage is being scared to death, but saddling up anyway." ~~ John Wayne )
[ Post Reply | Private Reply | To 53 | View Replies]

To: Vermont Lt

No, I would splash myself if I were in that predicament.


56 posted on 01/11/2022 2:03:58 PM PST by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
[ Post Reply | Private Reply | To 38 | View Replies]

To: ConservativeMind

You don’t want one with NO sedation. Trust me on that.


57 posted on 01/11/2022 2:14:24 PM PST by telescope115 (Proud member of the ANTIFAuci movement. )
[ Post Reply | Private Reply | To 1 | View Replies]

To: mass55th

Thank you and God Bless!


58 posted on 01/11/2022 2:18:07 PM PST by mmichaels1970
[ Post Reply | Private Reply | To 55 | View Replies]

To: ConservativeMind

I was putting off the colonoscopy and my doctor recommended
the Cologuard test.
They send you a kit.
And you mail off some poop.
They test it and can tell if there are precancerous lesions.

Insurance covers it. But I read that if it comes back positive, mine was negative, a colonoscopy is then required.
And it shifts the colonoscopy from being preventative to diagnostic and that can change insurance reimbursement, making the colonoscopy more expensive.


59 posted on 01/11/2022 2:28:00 PM PST by DannyTN
[ Post Reply | Private Reply | To 1 | View Replies]

To: JoSixChip

Yeah, I had a sigmoidoscopy once, where they use a shorter scope with no sedation, and brother, THAT hurt.


60 posted on 01/11/2022 2:33:07 PM PST by telescope115 (Proud member of the ANTIFAuci movement. )
[ Post Reply | Private Reply | To 18 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-4041-6061-76 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson