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Increasing incidence of early-onset colorectal precancerous lesions in patients under age 50
Medical Xpress / The Mount Sinai Hospital / Gastroenterology ^ | Jan. 11, 2022 | Steven H. Itzkowitz, MD, FACP

Posted on 01/11/2022 12:02:15 PM PST by ConservativeMind

Researchers describe a troubling increase in early-onset colorectal cancer and precancerous polyps, based on a large, nationally representative study of patients under age 50 who underwent colonoscopy. It was the first large-scale study to look at precancerous polyps in this age group.

"We have known for many years that rates of colorectal cancer are rising in individuals younger than 50, prompting several medical organizations to recommend lowering the screening age from 50 to 45. What has been missing until now is confirmatory data of the prevalence of precancerous polyps in younger individuals. Because precancerous lesions are not reportable to regional or national health agencies, we have not had this degree of information to guide our recommendations. Our study provides an important piece of the puzzle and supports the recommendation changing the screening age to 45," says lead author Steven H. Itzkowitz, MD. "Our findings also suggest that messaging aimed at young individuals should begin in the years leading up to this new screening age. We know that most patients do not call their doctors on their 50th birthday to schedule a colonoscopy, so we will need to be diligent to reach this much younger cohort before they turn 45," says Dr. Itzkowitz.

Increasing age, being male and white, having a family history of colorectal cancer, and having had colonoscopies for reasons of bleeding or screening, were all associated with higher odds of advanced premalignant lesions (APLs) and colorectal cancer. Among patients aged 45-49, 32 percent had neoplasia (precancerous or cancerous lesions considered forerunners to colorectal cancer). Nearly 8 percent had APLs, and 0.58 percent had colorectal cancer.

Early-onset colorectal cancer accounts for approximately 12 percent of all colorectal cancer cases, with incidence increasing by 2.2 percent annually from 2012-2016, and mortality increasing by 1.3 percent per year from 2008-2017.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: colonoscopy; colorectalcancer; polyps
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I have been told to get a colonoscopy, but I am having problems finding one who will do it with light or no sedation.
1 posted on 01/11/2022 12:02:15 PM PST by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The β€œTake Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to implement for your benefit.

Please email or private message me if you want on or off of this list.

2 posted on 01/11/2022 12:02:41 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Two things that I can see. First, more screening means more detection. Second, genetically modified food and the standard American diet results in a myriad of health problems.


3 posted on 01/11/2022 12:05:42 PM PST by refreshed (But we preach Christ crucified... 1 Corinthians 1:23)
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To: ConservativeMind
It was the first large-scale study to look at precancerous polyps in this age group.

Call me crazy, but if this is the first study of this age group, then how can they claim a "troubling increase" in the polyps?

4 posted on 01/11/2022 12:07:45 PM PST by Yo-Yo (is the /sarc tag really necessary?)
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To: Yo-Yo

Perhaps the people who chose to take colonoscopy before age 45 are a specific subset, not characteristic of entire population.... so recommendations based on this “a postiori” analysis are skewed/not valid.

I say this because I chose to take the colonoscopy at age 45 because grandmother was diagnosed & treated for colon cancer.


5 posted on 01/11/2022 12:14:13 PM PST by mason-dixon (As Mason said to Dixon, you have to draw the line somewhere.)
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To: ConservativeMind

Believe me, you’ll want the sedation


6 posted on 01/11/2022 12:16:31 PM PST by HonorInPa
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To: Yo-Yo

Call me crazy, but if this is the first study of this age group, then how can they claim a “troubling increase” in the polyps?

~~~

Because they think no one will click if you don’t have something scary or sensation in your headline


7 posted on 01/11/2022 12:17:51 PM PST by z3n (Kakistocracy)
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To: mason-dixon

I was confused by the conflicting claims that there is a “troubling increase” in polyps, yet this is the first large scale study of the age group.

To what are they comparing this study in order to come to the conclusion that there is a “troubling increase?”

Normally, you would need to compare the results of this study to past studies of a similar nature before you could confidently detect a trend.


8 posted on 01/11/2022 12:18:07 PM PST by Yo-Yo (is the /sarc tag really necessary?)
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To: ConservativeMind
I am having problems finding one who will do it with light or no sedation.

They have it down to a science, the doctor walks in, the nurse says count to ten, by 3 your out. Next thing you remember is the doctor standing at your bed when you wake up at the exact time he begins speaking.

9 posted on 01/11/2022 12:18:34 PM PST by 1Old Pro (Let's make crime illegal again!)
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To: ConservativeMind

No thanks - but considering I’ve had two radial approach catheterizations with nothing but Versed on board (fully awake and could feel the thing bumping against my heart at times), I don’t know why a proctologist wouldn’t do a scope with light sedation.


10 posted on 01/11/2022 12:22:17 PM PST by jagusafr ( )
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To: 1Old Pro; ConservativeMind
They have it down to a science, the doctor walks in, the nurse says count to ten, by 3 your out. Next thing you remember is the doctor standing at your bed when you wake up at the exact time he begins speaking.

Slightly different experience. Had one a week ago (first time). They told me they were administering the drug (Fentanyl). I felt no different. I felt awake during the entire procedure but felt no pain. I'd have sworn I wasn't sedated at all. Had my glasses removed so all I felt was blind. Got wheeled back to my bed and dressed almost immediately. About 1 hour, 10 minutes from the time I put on my gown til discharge. I easily pointed out my ride and my car as they wheeled me out.

And I don't remember ANYTHING about the 10 minute ride home. Nothing. My ride said I spoke normally all the way. But that 10 minutes is gonzo.
11 posted on 01/11/2022 12:28:20 PM PST by mmichaels1970
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To: ConservativeMind

Big Pharma invented modern day “cancer” 100 years ago - create the problem that you sell the drugs to “cure”.


12 posted on 01/11/2022 12:29:26 PM PST by C210N (Everything will be okay in the end. If it’s not okay, it’s not the end.)
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To: 1Old Pro

For both mine (last year and five years ago), I don’t remember completely going under. I was in kind of a netherworld where I faded in and out. I’d occasionally wake up for a few seconds and look at the screen and then fade back out.

But when the nurse called my name when it was done, I woke up immediately.


13 posted on 01/11/2022 12:29:49 PM PST by MplsSteve
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To: ConservativeMind
"I have been told to get a colonoscopy, but I am having problems finding one who will do it with light or no sedation."

You cannot party hard and let your freak flag fly if the patient is awake....

14 posted on 01/11/2022 12:30:03 PM PST by WMarshal ("Those who would give up essential liberty, to purchase a little temporary safety, deserve neither.")
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To: ConservativeMind; refreshed
I think I see the problem....


15 posted on 01/11/2022 12:31:07 PM PST by 4Liberty (Let's go Brandon πŸ‘ ...πŸ‘ ...πŸ‘πŸ‘πŸ‘ https://youtu.be/qr_F_XQrukM?t=1)
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To: ConservativeMind

16 posted on 01/11/2022 12:32:09 PM PST by WMarshal ("Those who would give up essential liberty, to purchase a little temporary safety, deserve neither.")
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To: ConservativeMind

Had mine done just yesterday! For me, the sedation was a much appreciated nap. As an aside, they found higher than average polyps, which surprised me cuz I’m not a big red meat eater. Hope you get yours, soon!


17 posted on 01/11/2022 12:32:38 PM PST by LittleBillyInfidel (This tagline has been formatted to fit the screen. Some content has been edited.)
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To: jagusafr

Because they blow your colon up like a balloon. The pain would drive you insane. They use the Michael Jackson drug to knock you out. You go to sleep instantly, and you wake-up instantly with no hangover and your head is clear, like after a good night’s sleep.


18 posted on 01/11/2022 12:34:11 PM PST by JoSixChip (2020: The year of unreported truths; 2021: My main take away from this year? Trust no one.)
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To: 4Liberty


19 posted on 01/11/2022 12:34:49 PM PST by 4Liberty (Let's go Brandon πŸ‘ ...πŸ‘ ...πŸ‘πŸ‘πŸ‘ https://youtu.be/qr_F_XQrukM?t=1)
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To: ConservativeMind
The worst part of a colonoscopy is the fasting and prep the night before. I'm 74, and have had colonoscopies regularly since I was 50, because my father had polyps. On my last colonoscopy in June, they found a small polyp, and removed it. It was benign. The good news is that my doctor has said we can do the colorectal tests from now on, as long as there isn't a problem. My doctor also said that because of colon cancer appearing in younger people, they have lowered their screening age quite a bit.

My youngest son, age 48 at the time, was diagnosed with cancerous polyps in 2019. The doctor told him the polyps were so big, he'd wish he'd come to see him 10 years earlier. He would have been 38 at the time, but they didn't do cancer screening on people that young back then. My son had surgery...two re-sections. They also took out at least 70 lymph nodes, and he went through 6 months of chemo. He's cancer-free, but as a mother, I can't help but worry, because he still smokes occasionally. Everyone in my family smoked but me. Three died of lung cancer, one of a stroke, and my only brother at 51, of a massive heart attack. I'm the last one left. The oldest lived to be 74, so if I make it to 75, I'll be lucky.

20 posted on 01/11/2022 12:37:36 PM PST by mass55th ("Courage is being scared to death, but saddling up anyway." ~~ John Wayne )
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