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‘Game Changer’: Simple Eye Scan May Detect Alzheimer’s Earlier, Study Finds
www.studyfinds.org ^ | March 12, 2019 | Staff

Posted on 03/13/2019 10:17:38 AM PDT by Red Badger

DURHAM, N.C. — Your eyes may be the window to your soul, but thanks to new research, they may also be the key to detecting Alzheimer’s disease early on. Researchers at the Duke Eye Center say a simple eye scan may reveal activity in the brain associated with the debilitating condition.

Eye doctors may not only be fitting patients with glasses or contacts in the future, but they could also be routinely checking people for Alzheimer’s. The research team found that blood vessel activity in the eyes of Alzheimer’s patients is notably different from that within healthy individuals. ==========================================================

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“We know that there are changes that occur in the brain in the small blood vessels in people with Alzheimer’s disease, and because the retina is an extension of the brain, we wanted to investigate whether these changes could be detected in the retina using a new technology that is less invasive and easy to obtain,” says lead author Dr. Dilraj S. Grewal, M.D., an ophthalmologist and retinal surgeon at Duke, in a media release.

In healthy people, blood vessels form a dense web inside the retina, researchers say, but in patients with Alzheimer’s, that web is notably weaker. Using a noninvasive technology called optical coherence tomography angiography (OCTA), the authors were able to spot these differences when looking at the eyes of 133 healthy people, compared to 39 people with Alzheimer’s and 37 people with mild cognitive impairment. The OCTA eye scan allows doctors to take high-resolution images of the retina in just a few minutes and see blood vessel activity.

Changes in the blood vessel density in the retina could indicate similar activity within the brain that occurs in people with Alzheimer’s. But these changes may occur before symptoms become noticeable, such as changes in memory. That’s why the authors believe this eye scan could be groundbreaking.

“Early diagnosis of Alzheimer’s disease is a huge unmet need,” says senior author Dr. Sharon Fekrat, an ophthalmologist and retinal surgeon at Duke, in a statement to the American Academy of Ophthalmology. “It’s not possible for current techniques like a brain scan or lumbar puncture (spinal tap) to screen the number of patients with this disease. It is possible that these changes in blood vessel density in the retina may mirror what’s going on in the tiny blood vessels in the brain. Our work is not done. If we can detect these blood vessel changes in the retina before any changes in cognition, that would be a game changer.”

The study was published in the journal Ophthalmology Retina.


TOPICS: Arts/Photography; Computers/Internet; Education; Health/Medicine
KEYWORDS: eyeswindowtosoul; ophthalmology
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1 posted on 03/13/2019 10:17:38 AM PDT by Red Badger
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To: Red Badger

What am I missing here? Do they have a cure or treatment for Alzheimers if treated early?


2 posted on 03/13/2019 10:24:00 AM PDT by spudville
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To: Red Badger

Looks more like a vascular degeneration measurement. Alzheimer’s is not the only affliction that involves vascular degeneration.


3 posted on 03/13/2019 10:30:18 AM PDT by rjsimmon (The Tree of Liberty Thirsts)
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To: spudville

What am I missing here? Do they have a cure or treatment for Alzheimers if treated early?
______________

Exactly. What’s the point? So you can be miserable for a longer time?


4 posted on 03/13/2019 10:37:20 AM PDT by LydiaLong
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My wife’s eye doctor has a very sophisticated piece of equipment that makes very detailed digital images of the inner eye. And in one case he sent a patient directly to a hospital because of an impending stroke that he detected in one of those images. True story.


5 posted on 03/13/2019 10:49:18 AM PDT by Clutch Martin (The trouble ain't that there is too many fools, but that the lightning ain't distributed right.)
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To: spudville

You are right to query. There is nothing in the article to suggest that it would do any good to know ahead of time that you’re going to have Alzheimer’s. That, to me, would be worse than not knowing.


6 posted on 03/13/2019 10:59:51 AM PDT by Migraine
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To: spudville

I am glad, by the posts so far, that I am not the only one with the same exact opinion.

Personally, since there is no cure, I would much prefer not knowing while the cognitive process is still going on. Being just south of 73 years old the occasional thought/worry that I might even someday contract Alzheimer’s is quite enough, thank you.

Knowing I have it before the effects start showing would just make me morbid every waking second.


7 posted on 03/13/2019 11:10:01 AM PDT by ImpBill (A Party-less little "L" libertarian. Republicrats/Democans-A pox on both Party's!)
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To: Red Badger

So you scan and you detect it. Then what do you do? How is this helpful, there is no cure.


8 posted on 03/13/2019 11:17:50 AM PDT by ThePatriotsFlag (We are getting even more than we voted for.)
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To: ThePatriotsFlag

There are newer drugs that have been able to slow the progress............


9 posted on 03/13/2019 11:18:45 AM PDT by Red Badger (We are headed for a Civil War. It won't be nice like the last one....................)
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To: Red Badger

Without a cure, this simply gets folks into treatment $tatu$ sooner.

Like much of the a la cart medical testing, earlier detection means longer treatment time.

Much more lucrative than a cure......

.02
YMMV
KYPD


10 posted on 03/13/2019 11:19:38 AM PDT by petro45acp (Who is John Gantt? MBA nonsense that causes any efficient endeavour to bloat with "dependencies")
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To: Red Badger
My millions of dollars of research has absolutely proved that breathing will always eventually lead to death.

Can I have some more research money now?

11 posted on 03/13/2019 11:22:09 AM PDT by I cannot think of a name
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To: ThePatriotsFlag
One of the big problems with AZ is the slow and difficult process to diagnose.I know a couple that the wife swears the husband has AZ and no one else in their circle thinks he does. Causes a great deal of stress. A definitive test would stop or slow the talk down. Mostly I think he is just tired of listening to her
12 posted on 03/13/2019 11:22:11 AM PDT by mad_as_he$$
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To: I cannot think of a name

Only if you tell us it causes climate change.................


13 posted on 03/13/2019 11:24:57 AM PDT by Red Badger (We are headed for a Civil War. It won't be nice like the last one....................)
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To: AdmSmith; AnonymousConservative; Arthur Wildfire! March; Berosus; Bockscar; cardinal4; ColdOne; ...
Thanks Red Badger. That's nice, now it'll be possible to worry about it longer.

14 posted on 03/13/2019 11:36:48 AM PDT by SunkenCiv (this tagline space is now available)
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To: Red Badger
our eyes may be . . . Researchers . . say a simple eye scan may reveal . . Eye doctors . . could also be . . Changes . could indicate . . these changes may occur . . authors believe . . It is possible . . If we can . .

Pure hype, waiting for confirmation.

15 posted on 03/13/2019 12:44:19 PM PDT by aimhigh (THIS is His commandment . . . . 1 John 3:23)
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To: Red Badger
On a related note...

Could Alzheimer's Be a Reaction to Infection? A relatively new and still controversial theory suggests the disease could be triggered by pathogens

16 posted on 03/13/2019 12:47:30 PM PDT by mewzilla (Break out the mustard seeds.)
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To: mad_as_he$$

There are other forms of dementia in addition to Alzheimer’s. Here’s hoping the wife has hubby in to see a gerontologist for an eval.


17 posted on 03/13/2019 12:49:02 PM PDT by mewzilla (Break out the mustard seeds.)
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To: ThePatriotsFlag

Cure? If you are in a 20’ hole and have a 5’ ladder, you aren’t coming out no matter what.

For early & moderate ALZ there is a proven way out.

The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline Hardcover – August 22, 2017
by Dale Bredesen (Author)

https://www.amazon.com/End-Alzheimers-Program-Prevent-Cognitive/dp/0735216207?SubscriptionId=AKIAILSHYYTFIVPWUY6Q&tag=duckduckgo-osx-20&linkCode=xm2&camp=2025&creative=165953&creativeASIN=0735216207


18 posted on 03/13/2019 1:21:08 PM PDT by Bobibutu
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To: spudville

plenty of natural ways to slow it down, enjoy more life. people can change outcomes if they know sooner AND choose to act accordingly.


19 posted on 03/13/2019 1:27:36 PM PDT by b4me (God Bless the USA)
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To: mewzilla

Whenever I hear about some incurable disease, I think of ulcers.


20 posted on 03/13/2019 9:03:50 PM PDT by gogeo (Liberal politics and mental instability; coincidence, correlation, or causation?)
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