Posted on 09/29/2011 7:09:17 PM PDT by Pining_4_TX
Tight glucose control won't mitigate the cognitive effects of type 2 diabetes, an ACCORD subanalysis found.
Intensive treatment aiming for hemoglobin A1c under 6% did reduce brain atrophy over 40 months compared with standard management (P=0.0007), Lenore J. Launer, PhD, of the National Institute on Aging in Bethesda, Md., and colleagues found. But cognitive scores over 40 months showed no advantage over treatment to the conventional 7% to 7.9% goal (P=0.2997), they reported online in Lancet Neurology.
These results from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Memory in Diabetes (MIND) substudy matched the overall lack of benefit for cardiovascular outcomes with tight control of glucose, blood pressure, or lipids.
The trial even suggested harm from 19% excess mortality with tight glucose control at five years.
Altogether, "our findings do not support the use of intensive therapy to reduce the adverse effects of diabetes on the brain in patients with similar characteristics to those of our participants," Launer's group wrote.
(Excerpt) Read more at medpagetoday.com ...
ping
see what i mean now all of a sudden nothing is gonna work after so called trials !
Ping
Thanks, Pining.
What drives me crazy is that ‘tight control’ has been proven to be more dangerous than a constantly elevated BG.
And they just keep trying to make the old idea work.
The stress and pressure on a diabetic to keep things perfect isn’t good for them either.
“What drives me crazy is that ‘tight control’ has been proven to be more dangerous than a constantly elevated BG.”
Wow. What i*meant to say was,
What drives me crazy is that ‘tight control’ has been proven to be more dangerous than a SLIGHTLY elevated BG.
sheesh!
I have type 2 what drives me crazy is the medicine i take glyburide twice a day and you can set your clock on hunger 1/2 hour after i take th .e medicine my stomach and head tell me im starving
i have more stress trying not to eat than i do trying to keep my levels good its ridiculous
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