Leeds medics solve an ancient riddle – and offer new tool for diagnosis (finger clubbing)

University of Leeds ^ | May 28, 2008 | Unknown

[decimon]

Something else to worry about - finger clubbing.

[fishtank]

Finger clubbing - so this was NOT a story about alternative lifestyles?

Who’da thunk it?

[Ciexyz]

Marvels of modern science bump.

[decimon]

Finger clubbing - so this was NOT a story about alternative lifestyles?

Well...uhh...never mind.

[Red_Devil 232]

[decimon]

That doesn’t look good.

[buccaneer81]

This was on an episode of “House” last season.

[politicalwit]

This is by no means earth breaking news. I was raised in a household of medical professionals...my Dad was a cardiovascular physiologist and Mom is a radiologist. Shhot, I’ve known about clubbing of the digits as a clinical symptom of lung disease (particulary pronounced in COPD patients) since I was 5 years old.

[Gondring]

This is by no means earth breaking news. I was raised in a household of medical professionals...my Dad was a cardiovascular physiologist and Mom is a radiologist. Shhot, I’ve known about clubbing of the digits as a clinical symptom of lung disease (particulary pronounced in COPD patients) since I was 5 years old.

Oh yeah, they just chatted around the house about it being caused by inability to break down PGE2 but never got around to publishing it, right?

[politicalwit]

You might be surprised the discussions at mealtime. My Dad spent many years in physiological research in institutions such as McGill University, Dartmouth, University of Lund as well as Baylor School of Medicine-Dallas and the University of Texas Medical Branch-Galveston.

As I stated, clubbing of the digits due to pulmonary defects such as emphysema, asthma and CF has been a well documented for hundreds of years.

BTW...if you have ever had a heart attack and received the clot buster streptokinese or have ever had a P.T.C.A. (Percutaneous transluminal coronary angioplasty) you can thank my Dad.

[Fractal Trader]

I don’t know if this is a GGG candidate, but it’s pretty cool, regardless.

[SunkenCiv]

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[SunkenCiv]

Wow, sorry, while I was fooling around with other stuff I saw the topic in the menu, had my GGG way with it, and saw your ping to me when I reloaded the “My Comments” page. Thanks, Fractal Trader, good lookin’ out. :’)

[mass55th]

When I first looked at the title, I thought maybe the article was about some medieval form of punishment.

[ValerieTexas]

Great. Now I’ll be looking at everyone’s fingers for days.

[SunkenCiv]

Just don’t sniff ‘em, trust me.

[neverdem]

The Case of the Telltale Fingertips

Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy

[martin_fierro]

Lung cancer, heart disease, hyperthyroidism, various gastrointestinal diseases and many other conditions all result in finger clubbing.

My fingers.

OK, time to worry.

[martin_fierro]

Shhot, [sic] I’ve known about clubbing of the digits as a clinical symptom of lung disease (particulary pronounced in COPD patients) since I was 5 years old.

OK, OK, I'll bite:

"Fine, but what've you done lately?"

[decimon]

OK, OK, I'll bite:

No, no, that's pull my finger.