Posted on 05/02/2019 10:23:08 AM PDT by dfewfe
Using a mouse model of pancreatic cancer, researchers have zoomed in on a single gene that stopped aggressive pancreatic cancer from developing when the scientists removed it. holding the DNA concept illustration New research sheds light on the genetic drivers behind pancreatic cancer. Pancreatic cancer is an aggressive form of cancer that tends to be diagnosed quite late and often resists treatment.
According to the National Cancer Institute (NCI), pancreatic cancer is the fourth leading cause of cancer death in the United States. Some estimates predict that by 2020, pancreatic cancer will become the second leading cause of death.
The NCI estimate that in 2019 there will be 56,770 new cases of pancreatic cancer and 45,750 deaths resulting from it.
One of the main drivers behind pancreatic cancer is the so-called KRAS oncogene. But new research identifies another gene whose action is crucial for the development of this cancer.
Dr. Diane Simeone, who is the director of the Pancreatic Cancer Center at the New York University Langone Health's Perlmutter Cancer Center, is the corresponding author of this new research.
Dr. Simeone and her colleagues carried out a study in mice and human patient samples to examine the role of a gene called "ataxia-telangiectasia group D complementing" (ATDC) in pancreatic tumor formation.
The researchers will be publishing their findings in the journal Genes & Development.
(Excerpt) Read more at medicalnewstoday.com ...
I lost my brother to pancreatic cancer so this is very exciting news to me. May the hand of God guide the researchers.
Beware of two laws of human endeavor.
The law of unintended consequences.
And
Murphey’s Law.
What else does that gene do? tread carefully.
Exactly - I'd probably go with it if I had pancreatic cancer.
How do you "delete" it?
Design a virus to insert it into place... What could go wrong?
This would be unbelievably fantastic.
Guess nothing could go wrong. Trust your deep state health care system.
I didn’t know there were so many doctors and scientists on FreeRepublic. Interesting.
You might be better served googling the phrase “gene therapy.”
I’m not a doctor, but I did stay at a Holiday Inn Express last night.
“Exactly - I’d probably go with it if I had pancreatic cancer. “
If it is experimental and I had pancreatic cancer, I would volunteer.
Wonderful....
Fantastic.....
F*$(ing CURE SOMETHING!!!!!
Stop telling us it is our diet, our lifestyle, our FAULT!!!!! This work has been ongoing for EVER! There is obviously more money in treatment than cure (see diabetes 1/2). Someone close, little over a year from diagnosis to in the ground...price tag, skoshi over 1.5 million (Whipple,chemo, rad, chemo).
It is obviously genetic, it is obviously going to be cured genetically, stop teasing....get it done.
/rant
KYPD
To bad this did not come about before Steve Jobs lost his life, Apple has not been the same without his vision and creativity!!!!
I lost my uncle and then my cousin (son of that uncle) to this horrid cancer. I think for those who have been diagnosed, it’s sure worth a shot.
Have lost a few dear friends to pancreatic cancer. With a one-year survival rate of less than 5%, and a 5-year survival rate of under 1%; I'd go with it, too.
I miss the political opinions of Jobs.
May not too.
TYRELL
The facts of life. I’ll be blunt.
To make an alteration in the
evolvement of an organic life
system, at least by men, makers
or not, is fatal. A coding
sequence can’t be revised once
it’s established.
BATTY
Why?
TYRELL
Because by the second day of
incubation any cells that have
undergone reversion mutation
give rise to revertant colonies —
like rats leaving a sinking ship.
The ship sinks.
BATTY
What about E.M.S. recombination?
TYRELL
We’ve already tried it — ethyl
methane sulfonate is an alkylating
agent and a potent mutagen — it
created a virus so lethal the
subject was destroyed before we
left the table.
BATTY
Then a repressor protein that
blocks the operating cells.
TYRELL
Wouldn’t obstruct replication,
but it does give rise to an error
in replication so that the newly
formed DNA strand carries a
mutation and you’ve got a virus
again... but all this is academic...
you are made as well as we could
make you.
BATTY
But not to last?
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