Thanks, don't know if that's been checked but will have my wife pass on this idea. She has another sister who had thyroid problems years ago, maybe it runs in the family. This sister-in-law of mine with mental issues has been complaining of menopause, can't sleep and feels she's going crazy. Taking it out on others and driving them away. Used to be a sweet mild gal; not any more.
hypothyroidism wikipedia source: https://en.wikipedia.org/wiki/Symptoms_and_signs_of_Graves’_disease
Anxiety syndromes related to hyperthyroidism are typically complicated by major depression and cognitive decline, such as in memory and attention
Overall, reported symptoms vary from mild to severe aspects of anxiety or depression, and may include psychotic and behavioural disturbances:
Varying degrees of anxiety,[24] such as a very active mind,[4]irritability,[24] hyperactivity, agitation, restlessness, nervousness, distractible overactivity[36] and panic attacks.[37] In addition patients may experience vivid dreams and, occasionally, nightmares.
Depressive features of mental impairment, memory lapses,[24] diminished attention span,[24] fluctuating depression[36][38]
Emotional lability and in some patients hypomania,.[39]
The pathological well-being (euphoria) or hyperactivity may produce a state of exhaustion, and profound fatigue or asthenia chiefly characterizes the picture.[4]
Erratic behaviour may include intermittent rage disorder and mild attention deficit disorder,.[40] Some patients become hyperirritable and combative, which can precipitate accidents or even assaultive behaviour.[4]
In more extreme cases features of psychosis,[41] with delusions of persecution or delusions of reference,[42] and pressure of speech may present themselves. Rarely, patients develop visual or auditory hallucinations or a frank psychosis,[4] and may appear schizophrenic, lose touch with reality and become delirious,[2][36] Such psychotic symptoms may not completely clear up after the hyperthyroidism has been treated.[4] Paranoia and paranoid-hallucionary psychosis in hyperthyroidism usually have a manic disposition and it is therefore often not clear if the patient is experiencing a paranoid psychosis with depressive streaks, or a depression that has paranoid streaks.[2]
Treatment of hyperthyroidism typically leads to improvement in cognitive and behavioral impairments.[30] Agitation, inattention, and frontal lobe impairment may improve more rapidly than other cognitive functions. However, several studies confirm that a substantial proportion of patients with hyperthyroidism have psychiatric disorders or mental symptoms and decreased quality of life even after successful treatment of their hyperthyroidism.[24]