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Ivermectin as a SARS-CoV-2 Pre-Exposure Prophylaxis Method in Healthcare Workers: A Propensity Score-Matched Retrospective Cohort Study [Published August 26,2021]
CUREUS ^ | 08/26/2021 | Morgenstern et al

Posted on 08/26/2021 10:01:05 PM PDT by SeekAndFind

Abstract

Background: Ivermectin is a drug that has been shown to be active against coronavirus disease 19 (COVID-19) in previous studies. Healthcare personnel are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Therefore, we decided to offer them ivermectin as a pre-exposure prophylaxis (PrEP) method.

Purpose: Primary outcome was to measure the number of healthcare workers with symptomatic SARS-CoV-2 infection and a positive reverse transcription polymerase chain reaction (RT-PCR) COVID-19 test in the ivermectin group and in the control group. Secondary outcome was to measure the number of sick healthcare workers with a positive RT-PCR COVID-19 test whose condition deteriorated and required hospitalization and/or an Intensive Care Unit (ICU), or who died, in the ivermectin group and in the control group.

Material and methods: This observational and retrospective cohort study was carried out in two medical centers, Centro Medico Bournigal (CMBO) in Puerto Plata and Centro Medico Punta Cana (CMPC) in Punta Cana, Dominican Republic. The study began on June 29, 2020, and ended on July 26, 2020. A Statistical Package for Social Sciences (SPSS) Propensity Score Matching procedure was applied in a 1:1 ratio to homogeneously evaluate 271 healthcare personnel that adhered to a PrEP program with ivermectin at a weekly oral (PO) dose of 0.2 mg/kg, and 271 healthcare personnel who did not adhere to the program were assigned as a control group.

Results: In 28 days of follow-up, significant protection of ivermectin preventing the infection from SARS-CoV-2 was observed: 1.8% compared to those who did not take it (6.6%; p-value = 0.006), with a risk reduction of 74% (HR 0.26, 95% CI [0.10,0.71]).

Conclusions: These results suggest that compassionate use of weekly ivermectin could be an option as a preventive method in healthcare workers and as an adjunct to immunizations,

(Excerpt) Read more at cureus.com ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: ivermectin; prophylaxis; sarscov2
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To: SeekAndFind

Please add me to your ping list.


41 posted on 08/27/2021 5:28:24 AM PDT by georgiabelle
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To: SeekAndFind

Bookmark


42 posted on 08/27/2021 5:34:31 AM PDT by georgiabelle
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To: LilFarmer

if it’s rx’d offlabel, it’s experimental, with a different set of legal liabilities for the prescriber. Suing is a sport in California.

Other than studies being invalid against Delta, and the long time for serum levels to build, The major issue with ivermectin, is, people found getting HCQ too hard so they gave up on that and ivermectin is the last choice on the shelf. But folks that can’t get a rx for ivermectin will trot down to the feed store and become one of those 1000+ poison control center calls about 12 hours later because they didn’t think to look up the material data safety sheet for the product before they put things into themselves. Somebody online said it was ok. The same behavior was seen with the vapers that couldn’t source (or didn’t want to pay for quality assured) diy supplies so off to the feed store they went to really screw up their lungs. People aren’t smart. So for that and other reasons already stated, it’s just not something I’d champion for anyone outside the amazonian jungle or african savannah. We have better things.


43 posted on 08/27/2021 5:36:19 AM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: LilFarmer

Good for him (and you!!)

I’m much like your husband, but decided to get on a prophylactic regimen because I have no interest in taking any of the so called “vaccines” .

A week ago this last Monday we had dinner with a friend who two days later was diagnosed with covid. I had been using Ivermectin weekly, but then I upped my dosage to every other day as a precaution. So far, so good. I’m using the horse pasted kind, and mix it with applesauce.


44 posted on 08/27/2021 5:42:00 AM PDT by BlueMondaySkipper (Involuntarily subsidizing the parasite class since 1981, )
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To: DoodleDawg

They are the same grade. Why are you so susceptible to the preachings of the FDA? It’s pretty late in the game to still be trusting them.


45 posted on 08/27/2021 5:43:49 AM PDT by BlueMondaySkipper (Involuntarily subsidizing the parasite class since 1981, )
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To: mewzilla

“Docs might be refusing to prescribe because it’s not a covered countermeasure.”

Yep, they’ll get sued if anything goes wrong


46 posted on 08/27/2021 5:46:08 AM PDT by AppyPappy (How many fingers am I holding up, Winston? )
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To: BlueMondaySkipper
They are the same grade.

Of course they are.

Why are you so susceptible to the preachings of the FDA? It’s pretty late in the game to still be trusting them.

And I should accept the preaching of who exactly?

47 posted on 08/27/2021 5:46:55 AM PDT by DoodleDawg
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To: LilFarmer

Tell him he will enjoy the benefits of Zinc


48 posted on 08/27/2021 5:46:59 AM PDT by AppyPappy (How many fingers am I holding up, Winston? )
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To: AppyPappy

If lack of liability coverage is why there refusing to prescribe prophylaxes and/or treatments, that is truly despicable.

Note to docs: If you can’t find a pair, have your lawyers draw up liability waivers for patients willing to sign them. I would have no prob doing that for you gutless wonders.


49 posted on 08/27/2021 5:51:44 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: mewzilla

...they’re...


50 posted on 08/27/2021 5:52:05 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: DoodleDawg

“And I should accept the preaching of who exactly?”

Nobody.

You should not accept the preaching of anybody without discernment.

If you use discernment, you would have already determined that the FDA, CDC and Fraudci are not to be trusted. They are LIARS. They make crap up, and feed it to the gullible. Logic and intelligence would tell you that people who are proven to be untrustworthy should not be trusted, and in fact, everything they say should be viewed with great suspicion.

But here you are…

Now. Show me your proof that the Ivermectin in horse paste is different than the Ivermectin in other forms (you can’t). You’re simply parroting what the FDA told you. They HAVE to dismiss any and all other treatments for covid because if any are acknowledged to exist, the EULA becomes defunct, and their masters/ benefactors in big Pharma don”t make any money. All thinking people have caught on to the scam by now.

But here you are…


51 posted on 08/27/2021 6:18:08 AM PDT by BlueMondaySkipper (Involuntarily subsidizing the parasite class since 1981, )
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To: BlueMondaySkipper
Re: "There are literally dozens of studies."

From Europe and the USA?

When I see your dozens of studies published in Nature and The Lancet, we can continue this conversation.

52 posted on 08/27/2021 7:00:27 AM PDT by zeestephen
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To: ProtectOurFreedom; SeekAndFind; All

I heard a woman on TV ridiculing Ivermectin as a dog dewormer. Apparently she is not aware that this is being given to show dogs worth thoueands of dollars and to horses worth millions.


53 posted on 08/27/2021 7:15:21 AM PDT by gleeaikin
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To: blueplum

“ If it’s rx’d offlabel, it’s experimental, with a different set of legal liabilities for the prescriber. Suing is a sport in California.”

You use the word “experimental” in the context that it is unsafe and that is misleading. The vaccines are experimental AND have never been proven safe in humans using normal drug trial methodology . Big difference.

It is not illegal to prescribe drugs off label. My son takes a seizure med that was used off label by neurologists for years (now approved).

People are sue-happy in the US anyway, this is not a reason not to try something that has shown great promise.

“The major issue with ivermectin, is, people found getting HCQ too hard so they gave up on that and ivermectin is the last choice on the shelf.”

Based on what?

HCQ is no harder to get than ivermectin, and through the same channels. There are plenty of teledoctors who will prescribe it and it literally takes a few minutes. But it certainly could be easier to get from our family doctors if the FDA would approve it.

My doctor had not read ANY studies on ivermectin, only followed the CDC . I sent him studies, he actually took the time to read them, and now he is interested.

“But folks that can’t get a rx for ivermectin will trot down to the feed store and become one of those 1000+ poison control center calls about 12 hours later because they didn’t think to look up the material data safety sheet for the product before they put things into themselves”

I highly doubt this mainstream news article because we’ve seen this tactic with every potential treatment in the past 2 years.

There will always people that don’t know how to read doses, follow instructions, or buy the wrong med. Guess what, that happens with meds all the time. Even doctors and nurses have misdosed meds. This is a strawman argument.

By the way, have you read the material data safety sheet for the vaccine? How about the ingredient list?

“The same behavior was seen with the vapers that couldn’t source (or didn’t want to pay for quality assured) diy supplies so off to the feed store they went to really screw up their lungs.”

Red herring.

“People are stupid”

So the government should think for them, right? Are you a statist? You should not have freedom to choose (and freedom to suffer the consequences of your choice), because the nanny state knows what’s best for you?

Do you even see where this thinking leads? “People are too stupid to own guns because someone will get hurt” followed by random “stories” in the news meant to instill fear.

“So for that and other reasons already stated, it’s just not something I’d champion for anyone outside the amazonian jungle or african savannah.”

What does that even mean? It is already used in the US for other conditions - it is not some obscure, witch doctor medicine.

Japan’s Ministry of Health just approved its use for Covid based on the research. 30% of the world is using Covid: https://ivmstatus.com/

____

You may not realize it but you actually made an argument for the FDA to approve ivermectin for off-label use. If the horse paste is so scary, it is a simple fix. The CDC and the FDA could simply say it’s ok to try along with other therapies. The decades of studies in humans show it’s safe, the side effects are much less threatening than those of the vaccine as well as less prevalent.

BUT remember how much money they would lose. Pfizer’s contract locks them in to the “vaccine” even if effective treatments or a cure is found:

“Purchaser acknowledges and agrees that (i) Pfizer’s efforts to develop and manufacture the Product are aspirational in nature and subject to significant risks and uncertainties, and (ii) the fact that any other drug or vaccine to prevent, treat or cure COVID-19 infection is successfully developed or granted authorization earlier than the granting of Authorization for the Product shall not change the current situation of urgent needs for prevention of the spread of the COVID-19 infection that poses serious threats to and harmful effects on the lives and health of the general public.”

2.1b http://ti-health.org/wp-content/uploads/2021/05/Albania-Pfizer.pdf


54 posted on 08/27/2021 7:34:11 AM PDT by LilFarmer
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To: BobinIL
"I think I would rather go to tractor supply and buy the horse paste than order meds from India. Just me."M

Just an anecdote, I have gone to a couple of large, crowded conventions in Florida. Each time I took about 1 gram of ivermectin horse paste. I had no side effects, no Covid either. I also still test positive for Covid antibodies from when I was infected over a year ago. So this anecdote isn't about the efficacy of Ivermectin, its about its relative safety and lack, in my case, of side effects.

55 posted on 08/27/2021 7:47:12 AM PDT by Paradox (Don't call them mainstream, there is nothing mainstream about the MSM.)
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To: zeestephen

“ When I see your dozens of studies published in Nature and The Lancet, we can continue this conversation.”

Oh. And here I thought Freepers thought for themselves. You apparently have outsourced your knowledge base to others. Do you get reimbursed for the wool they shear from you?

Search is your friend. You should try it sometime. Japan, India, Mexico City, have all been in the news telling about their move to Ivermectin and how successful it’s been. You miss those or just don’t believe because you’re suckered in by your masters?

You should probably take the jab like the good little lamb you are. You might have already done so…


56 posted on 08/27/2021 9:21:12 AM PDT by BlueMondaySkipper (Involuntarily subsidizing the parasite class since 1981, )
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To: BlueMondaySkipper
Search is my friend?

Actually, a global map is my first friend on this subject.

Every country that claims remarkable success with Ivermectin is in a tropical latitude.

Climate and parasites absolutely have a significant impact on COVID death and infection rates.

In addition, the USA and northern Europe set the gold standard for medical research.

Every year, several medical audit organizations rank countries for fraudulent or un-replicable medical research.

India and Mexico have a terrible record.

Japan is always near the bottom of the group of advanced wealthy countries.

If you or any other American wants to preemptively take Ivermectin, I have no problem with that.

I will wait to read about it in Nature or The Lancet, first.

57 posted on 08/27/2021 10:40:37 AM PDT by zeestephen
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To: blueplum

58 posted on 08/27/2021 4:00:51 PM PDT by Fred Nerks (fair dinkum!)
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To: BlueMondaySkipper
Well said!

Show me your proof that the Ivermectin in horse paste is different than the Ivermectin in other forms (you can’t). You’re simply parroting what the FDA told you. They HAVE to dismiss any and all other treatments for covid because if any are acknowledged to exist, the EULA becomes defunct, and their masters/ benefactors in big Pharma don”t make any money. All thinking people have caught on to the scam by now.

59 posted on 08/27/2021 4:03:20 PM PDT by Fred Nerks (fair dinkum!)
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To: zeestephen; Candor7

What you need to ask is, did your government sign this agreement:

https://www.wionews.com/world/how-pfizer-tried-to-bully-argentina-and-brazil-in-exchange-for-vaccines-366037

Purchaser acknowledges and agrees that (i) Pfizer’s efforts to develop and manufacture the Product are aspirational in nature and subject to significant risks and uncertainties, and (ii) the fact that any other drug or vaccine to prevent, treat or cure COVID-19 infection is successfully developed or granted authorization earlier than the granting of Authorization for the Product shall not change the current situation of urgent needs for prevention of the spread of the COVID-19 infection that poses serious threats to and harmful effects on the lives and health of the general public.”

2.1b http://ti-health.org/wp-content/uploads/2021/05/Albania-Pfizer.pdf

Your so-called USA and Northern Europe gold standard for medical research has absolutely nothing to do with the EU authorisation for the experimental treatment under discussion, whereas Ivermectin has been successfully prescribed for a variety of needs for several decades.


60 posted on 08/27/2021 4:53:31 PM PDT by Fred Nerks (fair dinkum!)
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