WRONG, I end up with ALL THE GI SIDE EFFECTS from any topical drug application. Neurotin was put in a compound cream for Arthritis and it made me sick as a dog. Just the same as the Pills did. Same with the Fen patch, shut my bowel down/acid reflux just like pill Opioids do. It’s not been just those 2 but any drug that does the so called ‘by pass the stomach’ spiel they give, even a Estrogen Patch, I started puking acid with the first application, and it shut my bowel down in 2 weeks. ALL forms of Estrogen does that, pill, patch and shot. ZOSYN Zapped my vision for 3 weeks, and that is IV delivered. Took a full 5 weeks before I could see to drive. I had to stay in a dim room until the crap got out of my system my eyes were so sensitive to light with Blurred Vision. Adhesives especially EKG patches means HIVES that need Predisone. I can get by with a quick EKG but if they leave the monitor hooked up and the patches on, I will break out in Hives under them.
Think. I did NOT say that the skin patch not go into blood stream and avoid all tissues. Of course it gets to stomach and all tissues. But it does not start with digestive tract.
Wow, to have those bad effects from every substance. I sincerely hope you have a long healthy life! My friend is allergic to opiates and thus she doesn’t have the benefits they provide from pain or surgery. I love estrogen; it’s the sweet nice happy hormone for me. Been on it for many years due to pituitary tumor.