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Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation
cell ^
| 16 March 2017
| Thomas C. Boothby
Posted on 03/17/2017 1:50:15 PM PDT by JoeProBono
Tardigrades are microscopic animals that survive a remarkable array of stresses, including desiccation [extreme drying].
How tardigrades survive desiccation has remained a mystery for more than 250 years.
Trehalose, a disaccharide essential for several organisms to survive drying, is detected at low levels or not at all in some tardigrade species, indicating that tardigrades possess potentially novel mechanisms for surviving desiccation.
Here we show that tardigrade-specific intrinsically disordered proteins (TDPs) are essential for desiccation tolerance. TDP genes are constitutively expressed at high levels or induced during desiccation in multiple tardigrade species. TDPs are required for tardigrade desiccation tolerance, and these genes are sufficient to increase desiccation tolerance when expressed in heterologous systems.
TDPs form non-crystalline amorphous solids (vitrify) upon desiccation, and this vitrified state mirrors their protective capabilities.
Our study identifies TDPs as functional mediators of tardigrade desiccation tolerance, expanding our knowledge of the roles and diversity of disordered proteins involved in stress tolerance.
TOPICS: Pets/Animals; Science
KEYWORDS: biology; desiccation; disorderedproteins; extremophiles; life; tardigrades; tdps; trehalose; waterbears
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Tardigrades, also known as water bears, are strangely adorable microscopic creatures that are capable of withstanding some of the worst that nature can throw at them. Classified as extremophiles, they can survive freezing, total dehydration, radiation, and even the vacuum of space.
To: JoeProBono
I said the Threat Title WORD FOR WORD to my wife only a half hour ago.
What are the odds?
2
posted on
03/17/2017 1:53:09 PM PDT
by
dp0622
(The only thing an upper crust conservative hates more than a liberal is a middle class conservative)
To: JoeProBono
Next big thing for apartment dwellers: pets that live on/between glass microscope slides.
3
posted on
03/17/2017 1:53:49 PM PDT
by
txhurl
To: JoeProBono
I don’t know about the “strangely adorable” part.
4
posted on
03/17/2017 1:57:49 PM PDT
by
dainbramaged
(Get out of my country now)
To: JoeProBono
5
posted on
03/17/2017 1:59:23 PM PDT
by
gaijin
To: dp0622; JoeProBono; All
"Tardigrades Use
Intrinsically Disordered Proteins
to Survive Desiccation...."
6
posted on
03/17/2017 2:00:36 PM PDT
by
musicman
(The future is just a collection of successive nows.)
To: JoeProBono
7
posted on
03/17/2017 2:00:36 PM PDT
by
gaijin
To: musicman
8
posted on
03/17/2017 2:03:33 PM PDT
by
dp0622
(The only thing an upper crust conservative hates more than a liberal is a middle class conservative)
To: musicman
9
posted on
03/17/2017 2:22:46 PM PDT
by
JoeProBono
(SOME IMAGES MAY BE DISTURBING VIEWER DISCRETION IS ADVISED;-{)
To: JoeProBono
10
posted on
03/17/2017 2:25:09 PM PDT
by
musicman
(The future is just a collection of successive nows.)
To: JoeProBono
Tardigrades Use the New York Jets and the SF 49ers to Survive Desiccation (Intrinsically Disordered Pro-teams)
11
posted on
03/17/2017 2:27:36 PM PDT
by
PTBAA
To: JoeProBono
Ds and Fs and 0s are given as tardigrades.
12
posted on
03/17/2017 2:36:09 PM PDT
by
ThanhPhero
(All the s)
To: JoeProBono
Cool, so in a way, they turn into glass.
13
posted on
03/17/2017 2:39:59 PM PDT
by
Paradox
("Donald Trump", the biggest Strawman ever created.)
To: dp0622
You need to run out and buy 1 Powerball & one Mega Millions ticket. You will surely win both because their odds are better than the odds are for your feat from just 1/2 hour ago. 8>)
To: gaijin
15
posted on
03/17/2017 2:44:18 PM PDT
by
JoeProBono
(SOME IMAGES MAY BE DISTURBING VIEWER DISCRETION IS ADVISED;-{)
To: JoeProBono
Known as “extremophiles” . . . . . well, that explains everything now. The very reason Pelosi, Chuckie the clown, Maxine Waters, etc., WILL NOT GO AWAY - they are all EXTREMOPHILES !
16
posted on
03/17/2017 2:44:45 PM PDT
by
snooter55
(People may doubt what you say, but they will always believe what you do)
To: snooter55
17
posted on
03/17/2017 2:48:40 PM PDT
by
JoeProBono
(SOME IMAGES MAY BE DISTURBING VIEWER DISCRETION IS ADVISED;-{)
To: Robert DeLong
lol. Since I didn’t even now some of those words, you’re right. :)
18
posted on
03/17/2017 3:00:25 PM PDT
by
dp0622
(The only thing an upper crust conservative hates more than a liberal is a middle class conservative)
To: gaijin
AH!!!!!!!!!!!!!!!!!
Why does she have my 90 year old uncle nunzio’s arms?
19
posted on
03/17/2017 3:01:26 PM PDT
by
dp0622
(The only thing an upper crust conservative hates more than a liberal is a middle class conservative)
To: dp0622
LOL, well you won’t know the numbers that will be picked so I guess knowing is irrelevant. 8>)
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