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Professor Angelika Gründling, lead author of the research from the Department of Medicine at Imperial said: "The Staphylococcus aureus bacterium is a key pathogen and causes many serious infections in patients. With this research we now have a better understanding of how the bacteria cope with salt stress. Although this research is at an early stage, we hope this knowledge will someday help us to prevent food borne staphylococcal infections, as well as open new possibilities for a type of treatment that may work alongside antibiotics."

In the new study, published in the journal Science Signaling, the team looked at MRSA cells in the lab and found that a signalling molecule called cyclic di-AMP is critical for the process through which the bacteria regulate their salt levels.

Staphylococcus aureus are notoriously resistant to high-salt concentrations, although up until now scientists have been unclear why. In the current study the team revealed that when the signalling molecule detects the bacterium is in a high-salt environment, the molecule latches onto several 'transporter' proteins to signal to them to respond and protect the cell.

High salt concentrations act to pull water out of a cell - which is why we feel thirsty after eating salty foods.

1 posted on 08/18/2016 10:20:21 AM PDT by Tilted Irish Kilt
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...
Infectious Disease Ping

Scientists find a salty way to kill MRSA

2 posted on 08/18/2016 10:22:50 AM PDT by Tilted Irish Kilt ( British historian Arnold Toynbee - Civilisations die from suicide, not by murder.)
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To: Tilted Irish Kilt

Interesting article and concept.

Chicks and wrestlers know all about cells becoming either hydrophilic or hydrophobic due to salt content. It is the key to bloating at the cellular level.

Turns out forcing water is about as efficacious as Midol, which BTW no longer contains a muscle relaxant and thus is worthless. It’s just Ibuprofin now.

PS: Colloidal silver kills MRSA and always has, and MRSA will never become immune to it. Everybody should have some in their medical arsenal.


3 posted on 08/18/2016 10:28:42 AM PDT by T-Bone Texan (Don't be a lone wolf. Form up small leaderlesss cells ASAP !)
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To: Tilted Irish Kilt

The media will take this and run with a headline “Scientists determine that salt is a killer!”


8 posted on 08/18/2016 10:53:19 AM PDT by pepsi_junkie (ui)
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To: Tilted Irish Kilt

From last year, here’s the medieval remedy to MRSA. Of course, it costs so much less than the new treatment, so it’ll never show up as an option in your doctor’s regimen.

http://www.foxnews.com/health/2015/04/01/medieval-remedy-to-treat-eye-infections-found-to-kill-mrsa-superbug.html


9 posted on 08/18/2016 10:56:59 AM PDT by ColoCdn (Neco eos omnes, Deus suos agnoset)
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