Posted on 12/27/2015 8:13:24 PM PST by daisy12
DAVIE COUNTY, N.C. – Pertussis – commonly known as whooping cough – is a serious bacteria. It causes spasms of severe coughing, which can cause those who have it to vomit and lose breath. In the worst cases, it can be deadly. In recent weeks, it made its way to two schools in Davie County.
The first case was reported on December 7. Today, the school system reported 13 confirmed cases, 11 in Davie High School, and two in the early college.
--snip--
The spread of whooping cough is most easily prevented by receiving the DTaP shot. However – and this is particularly troubling – all 13 of the people confirmed to have Pertussis had gotten the vaccine.
(Excerpt) Read more at myfox8.com ...
You can not cure pertussis (whooping cough)with ascorbic acid (Vitamin C)
You may not always be infected with a resistant strain.
Someone else will be.
How do you think we got MRSA?
The current pertussis vaccine escape mutant has a mortality/morbity about 10X greater than the original strain. And the vaccine has zero effectiveness against it.
Try for a 100X strain?
But wait!, there’s more!
http://www.scientificamerican.com/article/baboon-study-reveals-new-shortcoming-of-pertussis-vaccine/
Thanks for your question.
MRSA and many other type of antibiotic restistance are plasmid mediated, the genes encoding these enzymes are easily transferable among different bacteria from different species of bacteria.
You may read this http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216585/
I’m fully aware of how MRSA came about.
My point was this: You will never outrun the microbes when you treat ‘disease’ by selecting against particular strains.
The microbes will win every single time.
I’m old enough to remember when suggesting that antibiotics had ‘stopped working’ in some cases was verboten heresy.
Which was met with suggestions to put antibiotics in the public water supply.
Thank G-d those nutjobs didn’t get their way.
http://wwwnc.cdc.gov/eid/article/7/7/pdfs/01-7708.pdf
Discusses the situation with pertussis.
I met the lead author at a conference in the late 90’s/early 00’s where he was discussing this very topic.
Antibiotics have their place.
As do vaccines.
Universal ‘strategies’ to control disease that select for this or that strain and rely on universal compliance for a feel good level of protection against some pathogen are a horribly bad idea.
Regardless of that strategy.
Measles and mumps are working their way around the current vaccines as well.
Take home conclusion paragraph from the CDC paper:
“Strains carrying nonvaccine-type pertactin or pertussis
toxin variants were not found in the prevaccination era.
Although the number of strains analyzed from this period was
limited, these data suggest that the nonvaccine-type variants
are not able to displace the vaccine-type strains in
unvaccinated populations (i.e., they have a lower fitness level,
or reproductive rate, in unvaccinated communities).
Alternatively, the nonvaccine-type strains may have evolved
relatively recently. Consistent with the first hypothesis, we
have observed that nonvaccine-type strains are less fit in
naive mice than vaccine-type strains. In immune mice the
difference in fitness between the two types of strains was
much less pronounced (unpublished data). Thus vaccination
has acted to shift the competitive balance between strains.”
She recommends sodium ascorbate. The Vitamin C doesn’t do anything to the pertussis bacteria. It helps clear out the toxins that the bacteria create.
Sodium ascorbate has the same function as ascorbic acid, the only difference is that it is the sodium salt of ascorbic acid. It has an E number (E301) in the ascorbic acid range E300 to E305.
Please explan how it can “clear out the toxins that the bacteria create”.
I provided a link with the information. You can read it at your leisure if you wish, written by an MD in internal medicine and nephrology, not me. It explains why she recommend sodium ascorbate and one other form of oral vitamin C and how and why pertussis makes you sick. She doesn’t say that vitamin c will cure pertussis or keep you from getting it, just makes it manageable for at home care.
inactivated pertussis cells (the bacteria that causes whooping cough) drove infection rates in the U.S. below one case per 100,000 people. But adverse side effects of those vaccines led to the development and introduction in the 1990s of acellular pertussis vaccines, which use just a handful of the bacteria’s proteins and bypass most of the side effects. (Currently given to children as part of the Tdap vaccine.)
The problem is, the newer vaccines might not block transmission. A January 2014 study in PNAS by another research team demonstrated that giving baboons acellular pertussis vaccines prevented them from developing symptoms of whooping cough but failed to stop transmission.
Building on that result, Althouse and Scarpino used whopping cough case counts from the CDC, genomic data on the pertussis bacteria, and a detailed epidemiological model of whooping cough transmission to conclude that acellular vaccines may well have contributed to — even exacerbated — the recent pertussis outbreak by allowing infected individuals without symptoms to unknowingly spread pertussis multiple times in their lifetimes.
"There could be millions of people out there with just a minor cough or no cough spreading this potentially fatal disease without knowing it," said Althouse. "The public health community should act now to better assess the true burden of pertussis infection."
What's worse, their model shows that if the disease can be spread through vaccinated, asymptomatic individuals essentially undetected, the level of vaccination needed to protect those that are unvaccinated (so-called ‘herd immunity’) is over 99 percent, impractically high at a time when anti-vaccine campaigns are turning people away from vaccination.
Does this mean the current vaccine is useless? Not at all, the pair says. Until researchers can develop a new pertussis vaccine that blocks transmission, the protection the acellular vaccine offers to individuals is vital.
‘It's the symptoms of pertussis infection that kill people,’ Scarpino says, ‘and the existing vaccine prevents the most debilitating effects of whooping cough.’
In that sense, the research underscores the importance of getting vaccinated, especially for children. "There are lots of people out there who may be transmitting pertussis unknowingly," Scarpino says. "Not vaccinating your own child puts her or him at increased risk of severe disease, even death."
http://www.eurekalert.org/pub_releases/2015-06/sfi-swc062215.php
However, in the case of an ongoing infection there is good news:
A team of researchers from The University of Texas at Austin and Synthetic Biologics Inc. have developed two antibodies to potentially treat or prevent pertussis, the highly contagious respiratory tract infection that affects millions of infants around the world and results in an estimated 200,000 child deaths every year.
http://www.eurekalert.org/pub_releases/2015-12/uota-te120215.php
Covering their tracks there.
What my cat does in the litterbox.
Fact is, they’ve known that the current vaccine was losing its effectiveness for nearly 20 years. Even before the acellular one.
Dr. Mooi has had a research grant to study this very thing since the early/mid 90’s. That they act all shocked now belies the fact they’ve been funding studies of this very thing (with pretty strong conclusions to the affirmative) for two decades.
The same sorts of ‘denial and obfuscation’ occurred when it began to be apparent that antibiotics were losing their effectiveness as well.
It’s what monolithic organizations do.
The really cool part of Dr. Mooi’s research is apparently being vaccinated makes you MORE susceptible to the escape mutant with 10X mortality and morbidity.
Here J Mol Med (Berl). 2015 Apr;93(4):395-402.Complement evasion by Bordetella pertussis: implications for improving current vaccines. Dr Mooi et.al
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366546/
proposes the using of complement modulating proteins such as Vag8 ( http://www.uniprot.org/uniprot/O66044 ) in new vaccines.
Bah, you just didn’t follow the links she supplied to her own report regarding the treatment of pertussis at the bottom of that page.
I did.
Only buys time.
Doesn’t solve the underlying problem.
When your method for controlling bugs involves any sort of selection at all, you’re playing the game with ‘bug rules’. The bugs will always win when you play the game with their rules.
Never compete, genomically, with a microbe. They have tens, hundreds and possibly thousands of iterations per day to figure out your immune system. You have, at best, one generation every 16 years. They’re throwing genomic spaghetti at the wall with far greater efficiency than humans. They will always win this game when you play by their rules.
Excepting pandemics (smallpox, ebola, etc) the ‘ordinary’ bugs have evolved in a microbial milieu to survive in the presence of our immune system. Likewise we have evolved to survive the predations of them. The predominant strains are those with the least mortality and morbidity. Both from a fitness of the microbe standpoint and a selection against unfit humans. It’s been, at best, an uneasy truce. Modern medicine is now flinging grenades at an enemy they barely understand and essentially hoping for the best. Or at least kicking the can down the road for someone else. One day, sooner or later, a common microbe will turn rabid. We’ll definitely have preferred the ordinary microbe when that happens.
Pertussis is winning the current battle bigtime. We have ‘zero’ vaccines effective against the current escape mutant.
Moreover, the current vaccine selects FOR susceptibility.
Not. Winning. Are. We.
I guess we have to agree to disagree.
I worked in the field with some brilliant people.
Published with some of them too.
What they didn’t do, any of them, was worship at the altar of ‘accepted science’.
It’s why they were researchers.
And I’ll let you in on a little secret. Lots of microbiologist researchers...don’t have fully vaxed kiddos.
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